(Q28266284)

Future Medicinal Chemistry

PubMed

published in

1 reference

Identification of a nuclear receptor that is activated by farnesol metabolites

PubMed

cites work

1 reference

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

21 January 2018

1 reference

Targetting farnesoid-X-receptor: from medicinal chemistry to disease treatment

21 January 2018

1 reference

Targeting farnesoid X receptor for liver and metabolic disorders.

21 January 2018

1 reference

Bile acids: regulation of synthesis

21 January 2018

1 reference

Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration

21 January 2018

1 reference

The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution

21 January 2018

1 reference

Metabolic regulation by the nuclear receptor corepressor RIP140.

21 January 2018

1 reference

Farnesoid X receptor: from structure to potential clinical applications

21 January 2018

1 reference

Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure-activity relationship of a series of body and side chain modified analogues of chenodeoxycholic acid

21 January 2018

1 reference

The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone

21 January 2018

1 reference

Conformationally constrained farnesoid X receptor (FXR) agonists: Naphthoic acid-based analogs of GW 4064

21 January 2018

1 reference

The novel compounds that activate farnesoid X receptor: the diversity of their effects on gene expression.

21 January 2018

1 reference

Identification of a potent synthetic FXR agonist with an unexpected mode of binding and activation

21 January 2018

1 reference

Identification of gene-selective modulators of the bile acid receptor FXR.

21 January 2018

1 reference

T0901317 is a dual LXR/FXR agonist

21 January 2018

1 reference

The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis

21 January 2018

1 reference

Benefit of farnesoid X receptor inhibition in obstructive cholestasis

21 January 2018

1 reference

Farnesoid X receptor suppresses constitutive androstane receptor activity at the multidrug resistance protein-4 promoter.

21 January 2018

1 reference

Bile acid-activated receptors in the treatment of dyslipidemia and related disorders

21 January 2018

1 reference

Farnesoid X receptor represses hepatic lipase gene expression

21 January 2018

1 reference

The farnesoid X receptor induces very low density lipoprotein receptor gene expression

21 January 2018

1 reference

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

The farnesoid X receptor promotes adipocyte differentiation and regulates adipose cell function in vivo

21 January 2018

1 reference

Antiatherosclerotic effect of farnesoid X receptor

21 January 2018

1 reference

Activation of farnesoid X receptor prevents atherosclerotic lesion formation in LDLR-/- and apoE-/- mice

21 January 2018

1 reference

Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity

21 January 2018

1 reference

Lowering bile acid pool size with a synthetic farnesoid X receptor (FXR) agonist induces obesity and diabetes through reduced energy expenditure

21 January 2018

1 reference

The bile acid sensor FXR regulates insulin transcription and secretion

21 January 2018

1 reference

The nuclear receptor FXR is expressed in pancreatic beta-cells and protects human islets from lipotoxicity

21 January 2018

1 reference

Nonalcoholic fatty liver disease: from steatosis to cirrhosis

21 January 2018

1 reference

A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis

21 January 2018

1 reference

The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis

21 January 2018

1 reference

The hypolipidemic natural product guggulsterone is a promiscuous steroid receptor ligand

21 January 2018

1 reference

Theonellasterols and conicasterols from Theonella swinhoei. Novel marine natural ligands for human nuclear receptors.

21 January 2018

1 reference

Discovery of sulfated sterols from marine invertebrates as a new class of marine natural antagonists of farnesoid-X-receptor

21 January 2018

1 reference

Discovery that theonellasterol a marine sponge sterol is a highly selective FXR antagonist that protects against liver injury in cholestasis

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.4155/FMC.12.41

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

22571613

1 reference

Consolidated OpenCitations Corpus – April 2017