(Q28269619)

1

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Lei Zhang

2

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Paul J A Erbel

3

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Kan Ding

5

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Joseph A Garcia

6

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Richard K Bruick

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

28 October 2005

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published in

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volume

280

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issue

43

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page(s)

36047-54

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cites work

Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Differential roles of hypoxia-inducible factor 1alpha (HIF-1alpha) and HIF-2alpha in hypoxic gene regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Differentiating the functional role of hypoxia-inducible factor (HIF)-1alpha and HIF-2alpha (EPAS-1) by the use of RNA interference: erythropoietin is a HIF-2alpha target gene in Hep3B and Kelly cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Oxygen sensing in the hypoxic response pathway: regulation of the hypoxia-inducible transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

HIFalpha targeted for VHL-mediated destruction by proline hydroxylation: implications for O2 sensing

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O2-regulated prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Hypoxia inducible factor-alpha binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Activation of HIF1alpha ubiquitination by a reconstituted von Hippel-Lindau (VHL) tumor suppressor complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Mechanism of regulation of the hypoxia-inducible factor-1 alpha by the von Hippel-Lindau tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Ubiquitination of hypoxia-inducible factor requires direct binding to the beta-domain of the von Hippel-Lindau protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Asparagine hydroxylation of the HIF transactivation domain a hypoxic switch

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

A conserved family of prolyl-4-hydroxylases that modify HIF

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Hypoxia-inducible factor (HIF) asparagine hydroxylase is identical to factor inhibiting HIF (FIH) and is related to the cupin structural family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Contribution of the Per/Arnt/Sim (PAS) domains to DNA binding by the basic helix-loop-helix PAS transcriptional regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Signal transduction in hypoxic cells: inducible nuclear translocation and recruitment of the CBP/p300 coactivator by the hypoxia-inducible factor-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Aryl hydrocarbon nuclear translocator (ARNT) promotes oxygen-independent stabilization of hypoxia-inducible factor-1alpha by modulating an Hsp90-dependent regulatory pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

The PAS domain confers target gene specificity of Drosophila bHLH/PAS proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Structural basis for PAS domain heterodimerization in the basic helix-loop-helix-PAS transcription factor hypoxia-inducible factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

The human hypoxia-inducible factor 1alpha gene: HIF1A structure and evolutionary conservation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

HIF1A gene transcription is dependent on a core promoter sequence encompassing activating and inhibiting sequences located upstream from the transcription initiation site and cis elements located within the 5'UTR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Expression of the gene encoding the proapoptotic Nip3 protein is induced by hypoxia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Selection and analysis of a mutant cell line defective in the hypoxia-inducible factor-1 alpha-subunit (HIF-1alpha). Characterization of hif-1alpha-dependent and -independent hypoxia-inducible gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Hsp90 inhibitors as novel cancer chemotherapeutic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Subcellular localization and regulation of hypoxia-inducible factor-2alpha in vascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Targeting HIF-1 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Purification and characterization of hypoxia-inducible factor 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Hypoxia--a key regulatory factor in tumour growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

HIF-1 as a target for drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Structural basis for Hif-1 alpha /CBP recognition in the cellular hypoxic response

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Binding of natively unfolded HIF-1alpha ODD domain to p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

JPred: a consensus secondary structure prediction server

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200

Structure and Interactions of PAS Kinase N-Terminal PAS Domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M501755200