(Q28272747)

5

object named as

Leonard Neckers

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author name string

Jean-Baptiste Lattouf

1

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Ramaprasad Srinivasan

2

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W Marston Linehan

Identification of a 60-kilodalton stress-related protein, p60, which interacts with hsp90 and hsp70

4

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language of work or name

English

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publication date

November 2006

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published in

Nature Reviews Urology

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volume

3

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issue

11

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page(s)

590-601

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cites work

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

A phase II trial of 17-allylamino-17- demethoxygeldanamycin in patients with hormone-refractory metastatic prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

Hereditary and sporadic papillary renal carcinomas with c-met mutations share a distinct morphological phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

Hsp90 & Co. - a holding for folding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Correlation of the survival of ovarian cancer patients with mRNA expression of the 60-kD heat-shock protein HSP-60.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Heat shock protein hsp70 in patients with axillary lymph node-negative breast cancer: prognostic implications

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Expression of heat shock protein 72 in renal cell carcinoma: possible role and prognostic implications in cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Heat shock protein 27 increases after androgen ablation and plays a cytoprotective role in hormone-refractory prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

HSP90 and the chaperoning of cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Hsp70 and Hsp90--a relay team for protein folding

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Role of the heat shock response and molecular chaperones in oncogenesis and cell death

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Structure and functional relationships of Hsp90.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

The assembly and intermolecular properties of the hsp70-Hop-hsp90 molecular chaperone complex

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Polyubiquitination and proteasomal degradation of the p185c-erbB-2 receptor protein-tyrosine kinase induced by geldanamycin

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Chaperone-dependent E3 ubiquitin ligase CHIP mediates a degradative pathway for c-ErbB2/Neu

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Multiple-target drugs: inhibitors of heat shock protein 90 and of histone deacetylase.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Inhibition of heat shock protein HSP90-pp60v-src heteroprotein complex formation by benzoquinone ansamycins: essential role for stress proteins in oncogenic transformation

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

The amino-terminal domain of heat shock protein 90 (hsp90) that binds geldanamycin is an ATP/ADP switch domain that regulates hsp90 conformation

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

HSP90 as a new therapeutic target for cancer therapy: the story unfolds

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

DT-Diaphorase expression and tumor cell sensitivity to 17-allylamino, 17-demethoxygeldanamycin, an inhibitor of heat shock protein 90

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Pharmacokinetics and pharmacodynamics of 17-demethoxy 17-[[(2-dimethylamino)ethyl]amino]geldanamycin (17DMAG, NSC 707545) in C.B-17 SCID mice bearing MDA-MB-231 human breast cancer xenografts

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

A high-affinity conformation of Hsp90 confers tumour selectivity on Hsp90 inhibitors

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Geldanamycin, a new antibiotic

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Inhibition of the oncogene product p185erbB-2 in vitro and in vivo by geldanamycin and dihydrogeldanamycin derivatives

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

The benzoquinone ansamycin 17-allylamino-17-demethoxygeldanamycin binds to HSP90 and shares important biologic activities with geldanamycin

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Phase I pharmacokinetic and pharmacodynamic study of 17-allylamino, 17-demethoxygeldanamycin in patients with advanced malignancies

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Phase I trial of 17-allylamino-17-demethoxygeldanamycin in patients with advanced cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Phase I and pharmacologic study of 17-(allylamino)-17-demethoxygeldanamycin in adult patients with solid tumors.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Phase I pharmacokinetic-pharmacodynamic study of 17-(allylamino)-17-demethoxygeldanamycin (17AAG, NSC 330507), a novel inhibitor of heat shock protein 90, in patients with refractory advanced cancers

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Comparison of 17-dimethylaminoethylamino-17-demethoxy-geldanamycin (17DMAG) and 17-allylamino-17-demethoxygeldanamycin (17AAG) in vitro: effects on Hsp90 and client proteins in melanoma models

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

In vivo antitumor efficacy of 17-DMAG (17-dimethylaminoethylamino-17-demethoxygeldanamycin hydrochloride), a water-soluble geldanamycin derivative

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Novobiocin and related coumarins and depletion of heat shock protein 90-dependent signaling proteins

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

A Nucleotide-dependent molecular switch controls ATP binding at the C-terminal domain of Hsp90. N-terminal nucleotide binding unmasks a C-terminal binding pocket

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

4-Amino derivatives of the Hsp90 inhibitor CCT018159.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Targeting wide-range oncogenic transformation via PU24FCl, a specific inhibitor of tumor Hsp90.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

The development of androgen-independent prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Androgen receptor signaling in androgen-refractory prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

In vivo amplification of the androgen receptor gene and progression of human prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

The androgen receptor in LNCaP cells contains a mutation in the ligand binding domain which affects steroid binding characteristics and response to antiandrogens

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

From HER2/Neu signal cascade to androgen receptor and its coactivators: a novel pathway by induction of androgen target genes through MAP kinase in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Her-2-neu expression and progression toward androgen independence in human prostate cancer.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

STAT3 mediates IL-6-induced neuroendocrine differentiation in prostate cancer cells .

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Detection and distribution of heat shock proteins 27 and 90 in human benign and malignant prostatic tissue

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Expression of the insulin-like growth factor I receptor and urokinase plasminogen activator in breast cancer is associated with poor survival: potential for intervention with 17-allylamino geldanamycin

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

17-Allylamino-17-demethoxygeldanamycin (17-AAG) is effective in down-regulating mutated, constitutively activated KIT protein in human mast cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Characterization of the combined cellular survival effects of benzoquinone-ansamycins and ionizing radiation.

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

von Hippel-Lindau disease

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Mutations of the VHL tumour suppressor gene in renal carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Classification of renal cell carcinoma: Workgroup No. 1. Union Internationale Contre le Cancer (UICC) and the American Joint Committee on Cancer (AJCC)

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Hereditary papillary renal carcinoma type I

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Hsp90 regulates a von Hippel Lindau-independent hypoxia-inducible factor-1 alpha-degradative pathway

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Heat shock proteins HSP27, HSP60, HSP70, and HSP90: expression in bladder carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Function of 90-kDa heat shock protein in cellular differentiation of human embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Heat shock induces differentiation of human embryonal carcinoma cells into trophectoderm lineages

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Hsp90 Regulates Androgen Receptor Hormone Binding Affinityin Vivo

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Hypoxia-induced activation of HIF-1: role of HIF-1alpha-Hsp90 interaction

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Modulation of Akt kinase activity by binding to Hsp90

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

The hsp90-binding antibiotic geldanamycin decreases Raf levels and epidermal growth factor signaling without disrupting formation of signaling complexes or reducing the specific enzymatic activity of Raf kinase

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Sensitivity of mature Erbb2 to geldanamycin is conferred by its kinase domain and is mediated by the chaperone protein Hsp90

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Growth factors acting via tyrosine kinase receptors induce HSP90 alpha gene expression

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Anomalous expression of the HLA-DR alpha and beta chains in ovarian and other cancers

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

Molecular variation of human HSP90alpha and HSP90beta genes in Caucasians

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021

A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90α

1 reference

https://api.crossref.org/works/10.1038%2FNCPURO0604

7 January 2021