(Q28272907)

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Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients

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scholarly article

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Population pharmacokinetics and pharmacogenetics of mycophenolic acid following administration of mycophenolate mofetil in de novo pediatric renal-transplant patients (English)

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pharmacokinetics

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based on heuristic

Michel Tsimaratos

7

object named as

Michel Tsimaratos

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Georges Deschênes

3

object named as

Georges Deschênes

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object named as

Wei Zhao

1

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Evelyne Jacqz-Aigrain

object named as

Evelyne Jacqz-Aigrain

13

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Georges Deschenes

3

object named as

Georges Deschênes

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Patrick Niaudet

6

object named as

Patrick Niaudet

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author name string

May Fakhoury

2

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Gwenaelle Roussey

4

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Karine Brochard

5

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Jean Luc André

8

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Sylvie Cloarec

9

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Pierre Cochat

10

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Albert Bensman

11

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Saïd Azougagh

12

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language of work or name

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publication date

November 2010

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The Journal of Clinical Pharmacology

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50

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11

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1280-91

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Mycophenolates in transplantation

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https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Mycophenolate mofetil and its mechanisms of action

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https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Mycophenolic Acid Pharmacodynamics and Pharmacokinetics Provide a Basis for Rational Monitoring Strategies

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https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Does the evidence support the use of mycophenolate mofetil therapeutic drug monitoring in clinical practice? A systematic review.

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https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Population pharmacokinetics of mycophenolic acid in kidney transplant pediatric and adolescent patients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Characterization of rat intestinal microsomal UDP-glucuronosyltransferase activity toward mycophenolic acid

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

The main role of UGT1A9 in the hepatic metabolism of mycophenolic acid and the effects of naturally occurring variants

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Identification of common polymorphisms in the promoter of the UGT1A9 gene: evidence that UGT1A9 protein and activity levels are strongly genetically controlled in the liver.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

The impact of uridine diphosphate-glucuronosyltransferase 1A9 (UGT1A9) gene promoter region single-nucleotide polymorphisms T-275A and C-2152T on early mycophenolic acid dose-interval exposure in de novo renal allograft recipients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Influence of nonsynonymous polymorphisms of UGT1A8 and UGT2B7 metabolizing enzymes on the formation of phenolic and acyl glucuronides of mycophenolic acid

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Cyclosporin A, but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Cyclosporine interacts with mycophenolic acid by inhibiting the multidrug resistance-associated protein 2.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Epirubicin glucuronidation and UGT2B7 developmental expression.

1 reference

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21 January 2018

Developmental aspects of human hepatic drug glucuronidation in young children and adults

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Developmental pharmacology--drug disposition, action, and therapy in infants and children

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Therapeutic drug monitoring of mycophenolate mofetil in transplantation

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Immunosuppressive therapy for paediatric transplant patients: pharmacokinetic considerations

1 reference

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21 January 2018

Patient characteristics influencing ciclosporin pharmacokinetics and accurate Bayesian estimation of ciclosporin exposure in heart, lung and kidney transplant patients.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Population pharmacokinetics and bayesian estimator of cyclosporine in pediatric renal transplant patients.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Population pharmacokinetics of cyclosporine in kidney and heart transplant recipients and the influence of ethnicity and genetic polymorphisms in the MDR-1, CYP3A4, and CYP3A5 genes.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

A three-step approach combining Bayesian regression and NONMEM population analysis: application to midazolam.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Extensions to the visual predictive check to facilitate model performance evaluation

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Sirolimus population pharmacokinetic/pharmacogenetic analysis and bayesian modelling in kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Comparison of high-performance liquid chromatography and enzyme-multiplied immunoassay technique to monitor mycophenolic acid in paediatric renal recipients.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Allometric scaling of xenobiotic clearance: uncertainty versus universality

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Comparison of the effects of tacrolimus and cyclosporine on the pharmacokinetics of mycophenolic acid

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Population pharmacokinetics of mycophenolic acid in renal transplant recipients.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Cyclosporine concentration-dependent increase in concentration ratio of mycophenolic acid acyl and phenol glucuronides to mycophenolic acid in stable kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Population pharmacokinetics and Bayesian estimation of mycophenolic acid concentrations in stable renal transplant patients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Maximum a posteriori bayesian estimation of mycophenolic acid pharmacokinetics in renal transplant recipients at different postgrafting periods

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Validation of an abbreviated pharmacokinetic profile for the estimation of mycophenolic acid exposure in pediatric renal transplant recipients.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Identification of the UDP-glucuronosyltransferase isoforms involved in mycophenolic acid phase II metabolism.

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Genetic polymorphism of UDP-glucuronosyltransferase 2B7 (UGT2B7) at amino acid 268: ethnic diversity of alleles and potential clinical significance

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

UGT1A9 -275T>A/-2152C>T polymorphisms correlate with low MPA exposure and acute rejection in MMF/tacrolimus-treated kidney transplant patients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Glucuronidation in humans. Pharmacogenetic and developmental aspects

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

UGT genotype may contribute to adverse events following medication with mycophenolate mofetil in pediatric kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Pharmacokinetics and protein adduct formation of the pharmacologically active acyl glucuronide metabolite of mycophenolic acid in pediatric renal transplant recipients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Time-dependent clearance of mycophenolic acid in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

Glucocorticoids interfere with mycophenolate mofetil bioavailability in kidney transplantation

1 reference

https://api.crossref.org/works/10.1177%2F0091270009357429

21 January 2018

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10.1177/0091270009357429

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