(Q28287646)

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Huntington's disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription

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Europe PubMed Central

Huntington's disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription (English)

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Huntington's disease

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author name string

Nitai P Bhattacharyya

1

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Manisha Banerjee

2

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Pritha Majumder

3

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language of work or name

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publication date

September 2008

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275

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17

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4271-9

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Onset and pre-onset studies to define the Huntington's disease natural history.

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin in health and disease

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Selective neuronal degeneration in Huntington's disease

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Protein aggregation and neurodegenerative disease

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Loss of normal huntingtin function: new developments in Huntington's disease research

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Apoptosis in Huntington's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Transcriptional signatures in Huntington's disease

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

The hunt for huntingtin function: interaction partners tell many different stories

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin-protein interactions and the pathogenesis of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Interacting proteins as genetic modifiers of Huntington disease

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

A protein interaction network links GIT1, an enhancer of huntingtin aggregation, to Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

HIP1: trafficking roles and regulation of tumorigenesis.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Current concepts in apoptosis: the physiological suicide program revisited.

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin-interacting protein 1-mediated neuronal cell death occurs through intrinsic apoptotic pathways and mitochondrial alterations

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https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Regulation of the proapoptotic activity of huntingtin interacting protein 1 by Dyrk1 and caspase-3 in hippocampal neuroprogenitor cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Recruitment and activation of caspase-8 by the Huntingtin-interacting protein Hip-1 and a novel partner Hippi

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Induction of apoptosis in cells expressing exogenous Hippi, a molecular partner of huntingtin-interacting protein Hip1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Degenerative phenotypes caused by the combined deficiency of murine HIP1 and HIP1r are rescued by human HIP1.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Homer1c interacts with Hippi and protects striatal neurons from apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Bifunctional apoptosis inhibitor (BAR) protects neurons from diverse cell death pathways

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Rybp interacts with Hippi and enhances Hippi-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

BLOC1S2 interacts with the HIPPI protein and sensitizes NCH89 glioblastoma cells to apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

The viral death protein Apoptin interacts with Hippi, the protein interactor of Huntingtin-interacting protein 1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Hippi is essential for node cilia assembly and Sonic hedgehog signaling

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Interaction of HIPPI with putative promoter sequence of caspase-1 in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Direct transcriptional activation of human caspase-1 by tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Role of p73 in regulating human caspase-1 gene transcription induced by interferon-{gamma} and cisplatin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Caspase-1 is a direct target gene of ETS1 and plays a role in ETS1-induced apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

RYBP, a new repressor protein that interacts with components of the mammalian Polycomb complex, and with the transcription factor YY1

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Huntingtin-interacting protein 1 influences worm and mouse presynaptic function and protects Caenorhabditis elegans neurons against mutant polyglutamine toxicity.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Increased caspase-2, calpain activations and decreased mitochondrial complex II activity in cells expressing exogenous huntingtin exon 1 containing CAG repeat in the pathogenic range

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Expression pattern of apoptosis-related markers in Huntington's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

Structural abnormalities in spermatids together with reduced sperm counts and motility underlie the reproductive defect in HIP1−/− mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2008.06563.X

21 January 2018

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10.1111/J.1742-4658.2008.06563.X

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