(Q28591926)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

title

NMDA receptor function and NMDA receptor-dependent phosphorylation of huntingtin is altered by the endocytic protein HIP1 (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

Glutamate receptor, ionotropic, NMDA2A (epsilon 1)

26 December 2019

main subject

phosphorylation

0 references

1 reference

Huntingtin interacting protein 1

GOA release 2020-03-11

1 reference

Glutamate receptor, ionotropic, NMDA2B (epsilon 2)

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

John Georgiou

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Michael R. Hayden

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

author name string

Martina Metzler

1

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Lu Gan

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

Tak Pan Wong

3

2 references

31 January 2017

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26 December 2019

Lidong Liu

4

2 references

31 January 2017

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26 December 2019

Jeffrey Helm

5

2 references

31 January 2017

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26 December 2019

Lili Liu

6

2 references

31 January 2017

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26 December 2019

Yushan Wang

8

2 references

31 January 2017

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26 December 2019

Nagat Bissada

9

2 references

31 January 2017

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26 December 2019

Kevin Cheng

10

2 references

31 January 2017

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26 December 2019

Yu Tian Wang

12

2 references

31 January 2017

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26 December 2019

John C Roder

11

1 reference

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26 December 2019

language of work or name

English

0 references

publication date

1 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

published in

Journal of Neuroscience

2 references

31 January 2017

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26 December 2019

volume

27

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

page(s)

2298-2308

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

issue

9

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro

26 December 2019

cites work

1 reference

12 December 2020

Rapid redistribution of glutamate receptors contributes to long-term depression in hippocampal cultures

1 reference

12 December 2020

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

1 reference

12 December 2020

Lithium activates the serine/threonine kinase Akt-1 and suppresses glutamate-induced inhibition of Akt-1 activity in neurons

1 reference

12 December 2020

Dynamin-dependent endocytosis of ionotropic glutamate receptors

1 reference

12 December 2020

Role of AMPA receptor cycling in synaptic transmission and plasticity

1 reference

12 December 2020

Huntingtin is required for normal hematopoiesis

1 reference

12 December 2020

Regulation of AMPA receptor-mediated synaptic transmission by clathrin-dependent receptor internalization

1 reference

12 December 2020

Developmentally regulated NMDA receptor-dependent dephosphorylation of cAMP response element-binding protein (CREB) in hippocampal neurons.

1 reference

12 December 2020

N-methyl D-aspartate receptor-mediated bidirectional control of extracellular signal-regulated kinase activity in cortical neuronal cultures

1 reference

12 December 2020

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice

1 reference

12 December 2020

HIP12 is a non-proapoptotic member of a gene family including HIP1, an interacting protein with huntingtin

1 reference

12 December 2020

The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration.

1 reference

12 December 2020

A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila.

1 reference

12 December 2020

Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization

1 reference

12 December 2020

Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD.

1 reference

12 December 2020

Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting

1 reference

12 December 2020

Neural activity and survival in the developing nervous system

1 reference

12 December 2020

Molecular determinants of NMDA receptor internalization

1 reference

12 December 2020

HIP1 functions in clathrin-mediated endocytosis through binding to clathrin and adaptor protein 2

1 reference

12 December 2020

The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis

1 reference

12 December 2020

Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins

1 reference

12 December 2020

HIP1 and HIP12 display differential binding to F-actin, AP2, and clathrin. Identification of a novel interaction with clathrin light chain

1 reference

12 December 2020

Phosphatidylinositol 3-kinase is a central mediator of NMDA receptor signalling to MAP kinase (Erk1/2), Akt/PKB and CREB in striatal neurones.

1 reference

12 December 2020

Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis

1 reference

12 December 2020

Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease

1 reference

12 December 2020

Extrasynaptic NMDARs oppose synaptic NMDARs by triggering CREB shut-off and cell death pathways

1 reference

12 December 2020

The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt.

1 reference

12 December 2020

Differential regulation of synaptic and extra-synaptic NMDA receptors

1 reference

12 December 2020

Activity-dependent NMDA receptor-mediated activation of protein kinase B/Akt in cortical neuronal cultures

1 reference

12 December 2020

Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD.

1 reference

12 December 2020

Coupling of extrasynaptic NMDA receptors to a CREB shut-off pathway is developmentally regulated

1 reference

12 December 2020

Chronic lithium treatment antagonizes glutamate-induced decrease of phosphorylated CREB in neurons via reducing protein phosphatase 1 and increasing MEK activities

1 reference

12 December 2020

Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease

1 reference

12 December 2020

Disruption of the endocytic protein HIP1 results in neurological deficits and decreased AMPA receptor trafficking

1 reference

12 December 2020

Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes

1 reference

12 December 2020

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin.

1 reference

12 December 2020

Potentiation of NMDA receptor-mediated excitotoxicity linked with intrinsic apoptotic pathway in YAC transgenic mouse model of Huntington's disease

1 reference

12 December 2020

Not just a sink: endosomes in control of signal transduction

1 reference

12 December 2020

alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid subtype glutamate receptor (AMPAR) endocytosis is essential for N-methyl-D-aspartate-induced neuronal apoptosis

1 reference

12 December 2020

Huntingtin interacting protein 1 (HIP1) regulates clathrin assembly through direct binding to the regulatory region of the clathrin light chain

1 reference

12 December 2020

Activity-dependent neuroprotection and cAMP response element-binding protein (CREB): kinase coupling, stimulus intensity, and temporal regulation of CREB phosphorylation at serine 133.

1 reference

12 December 2020

Huntingtin phosphorylation on serine 421 is significantly reduced in the striatum and by polyglutamine expansion in vivo

1 reference

12 December 2020

Nuclear Ca2+ and the cAMP response element-binding protein family mediate a late phase of activity-dependent neuroprotection.

1 reference

12 December 2020

Cdk5 phosphorylation of huntingtin reduces its cleavage by caspases: implications for mutant huntingtin toxicity

1 reference

12 December 2020

A positive feedback loop between glycogen synthase kinase 3beta and protein phosphatase 1 after stimulation of NR2B NMDA receptors in forebrain neurons

1 reference

12 December 2020

The synaptic localization of NR2B-containing NMDA receptors is controlled by interactions with PDZ proteins and AP-2.

1 reference

12 December 2020

Striatal neuronal apoptosis is preferentially enhanced by NMDA receptor activation in YAC transgenic mouse model of Huntington disease

1 reference

12 December 2020

Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models

1 reference

12 December 2020

Selective degeneration and nuclear localization of mutant huntingtin in the YAC128 mouse model of Huntington disease

1 reference

12 December 2020

Wild-type huntingtin protects neurons from excitotoxicity

1 reference

12 December 2020

Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421.

1 reference

12 December 2020

The role of receptor internalization in CD95 signaling

1 reference

12 December 2020

2B synaptic or extrasynaptic determines signalling from the NMDA receptor.

1 reference

12 December 2020

Replication of the neurochemical characteristics of Huntington's disease by quinolinic acid

1 reference

12 December 2020

Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures

1 reference

12 December 2020

1 reference

12 December 2020

Developmental changes in localization of NMDA receptor subunits in primary cultures of cortical neurons.

1 reference

12 December 2020

Calcium promotes cell survival through CaM-K kinase activation of the protein-kinase-B pathway

1 reference

12 December 2020

Blockade of NMDA receptors and apoptotic neurodegeneration in the developing brain.

1 reference

12 December 2020

10.1523/JNEUROSCI.5175-06.2007

Identifiers

DOI

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17329427%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

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26 December 2019

2 references

31 January 2017