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Apoptosis in Huntington's disease.
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
review article
1 reference
stated in
Europe PubMed Central
title
Apoptosis in Huntington's disease
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
main subject
Huntington's disease
0 references
apoptotic process
1 reference
based on heuristic
inferred from title
author
Miriam A Hickey
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
Marie-Françoise Chesselet
series ordinal
2
object named as
Marie Françoise Chesselet
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
retrieved
1 November 2019
publication date
1 April 2003
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
published in
Progress in Neuro-Psychopharmacology & Biological Psychiatry
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
volume
27
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
issue
2
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
page(s)
255-265
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
cites work
Modulation of apoptotic regulatory proteins and early activation of cytochrome C following systemic 3-nitropropionic acid administration
1 reference
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Crossref
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7 January 2021
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Severe deficiencies in dopamine signaling in presymptomatic Huntington's disease mice
1 reference
stated in
Crossref
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7 January 2021
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Morphology and compartmental location of cells exhibiting DNA damage after quinolinic acid injections into rat striatum
1 reference
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Crossref
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7 January 2021
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Neuronal nuclear DNA fragmentation in the aged canine brain: apoptosis or nuclear DNA fragility?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Aberrant interactions of transcriptional repressor proteins with the Huntington's disease gene product, huntingtin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
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inferred from DOI database lookup
Replicating Huntington's disease phenotype in experimental animals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
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inferred from DOI database lookup
Oxidative damage and metabolic dysfunction in Huntington's disease: selective vulnerability of the basal ganglia.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin and DRPLA proteins selectively interact with the enzyme GAPDH.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trinucleotide (CAG) repeat length is positively correlated with the degree of DNA fragmentation in Huntington's disease striatum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Characterization of progressive motor deficits in mice transgenic for the human Huntington's disease mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Transcriptional dysregulation in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human huntington disease gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Altered neurotransmitter receptor expression in transgenic mouse models of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Increased huntingtin protein length reduces the number of polyglutamine-induced gene expression changes in mouse models of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Epidermal immunization by a needle-free powder delivery technology: Immunogenicity of influenza vaccine and protection in mice
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Striatal interneurons in Huntington's disease: selective increase in the density of calretinin-immunoreactive medium-sized neurons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Glyceraldehyde 3-phosphate dehydrogenase abnormality in metabolically stressed Huntington disease fibroblasts.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Truncated N-terminal fragments of huntingtin with expanded glutamine repeats form nuclear and cytoplasmic aggregates in cell culture.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Trinucleotide repeats: mechanisms and pathophysiology
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
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7 January 2021
based on heuristic
inferred from DOI database lookup
Survival of basal ganglia neuropeptide Y-somatostatin neurones in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Premature aging in mice deficient in DNA repair and transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of the subcellular localization of huntingtin with a set of rabbit polyclonal antibodies in cultured mammalian cells of neuronal origin: comparison with the distribution of huntingtin in Huntington's disease autopsy brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sp1 and TAFII130 transcriptional activity disrupted in early Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Trinucleotide repeat length instability and age of onset in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inactivation of the mouse Huntington's disease gene homolog Hdh
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Kennedy's disease: caspase cleavage of the androgen receptor is a crucial event in cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High level expression of expanded full-length ataxin-3 in vitro causes cell death and formation of intranuclear inclusions in neuronal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin interacts with a family of WW domain proteins
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Possible organ and age-related epigenetic factors in Huntington's disease and colorectal carcinoma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proliferative and degenerative changes in striatal spiny neurons in Huntington's disease: a combined study using the section-Golgi method and calbindin D28k immunocytochemistry
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nuclear DNA fragmentation in Creutzfeldt-Jakob disease: does a mere positive in situ nuclear end-labeling indicate apoptosis?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
N-myc and c-myc expression in Alzheimer disease, Huntington disease and Parkinson disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas and Fas-L expression in Huntington's disease and Parkinson's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Calpain activation in Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for degenerative and regenerative changes in neostriatal spiny neurons in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p300/CBP/p53 interaction and regulation of the p53 response
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The influence of huntingtin protein size on nuclear localization and cellular toxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin interacting protein 1 induces apoptosis via a novel caspase-dependent death effector domain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Gln-Ala repeat transcriptional activator CA150 interacts with huntingtin: neuropathologic and genetic evidence for a role in Huntington's disease pathogenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early alterations in gene expression and cell morphology in a mouse model of Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abundant expression and cytoplasmic aggregations of [alpha]1A voltage-dependent calcium channel protein associated with neurodegeneration in spinocerebellar ataxia type 6
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Polyglutamine-expanded human huntingtin transgenes induce degeneration of Drosophila photoreceptor neurons.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
UVB irradiation-induced apoptosis increased in lymphocytes of Huntington's disease patients.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Altered proteasomal function due to the expression of polyglutamine-expanded truncated N-terminal huntingtin induces apoptosis by caspase activation through mitochondrial cytochrome c release
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIP1, a human homologue of S. cerevisiae Sla2p, interacts with membrane-associated huntingtin in the brain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tauroursodeoxycholic acid, a bile acid, is neuroprotective in a transgenic animal model of Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin is present in the nucleus, interacts with the transcriptional corepressor C-terminal binding protein, and represses transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mutant huntingtin expression in clonal striatal cells: dissociation of inclusion formation and neuronal survival by caspase inhibition.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase 3-cleaved N-terminal fragments of wild-type and mutant huntingtin are present in normal and Huntington's disease brains, associate with membranes, and undergo calpain-dependent proteolysis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Four deaths and a funeral: from caspases to alternative mechanisms.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence of T-lymphocyte functional impairment in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intranuclear huntingtin increases the expression of caspase-1 and induces apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interaction of Huntington disease protein with transcriptional activator Sp1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurological abnormalities in a knock-in mouse model of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic invertebrate models of age-associated neurodegenerative diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of polyglutamine-expanded Huntingtin activates the SEK1-JNK pathway and induces apoptosis in a hippocampal neuronal cell line
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased expression of striatal signaling genes in a mouse model of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Disruption of CREB function in brain leads to neurodegeneration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteasomal-dependent aggregate reversal and absence of cell death in a conditional mouse model of Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Length of huntingtin and its polyglutamine tract influences localization and frequency of intracellular aggregates
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis in neurodegenerative disorders
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mouse models of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decrease in striatal enkephalin mRNA in mouse models of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cleavage, aggregation and toxicity of the expanded androgen receptor in spinal and bulbar muscular atrophy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dentatorubral pallidoluysian atrophy (DRPLA) protein is cleaved by caspase-3 during apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Compartmental loss of NADPH diaphorase in the neuropil of the human striatum in Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of a very large trinucleotide repeat in a patient with juvenile Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interference by huntingtin and atrophin-1 with cbp-mediated transcription leading to cellular toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspase-1 slows disease progression in a mouse model of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ectopically expressed CAG repeats cause intranuclear inclusions and a progressive late onset neurological phenotype in the mouse.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CAG-polyglutamine-repeat mutations: independence from gene context
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expanded polyglutamines in Caenorhabditis elegans cause axonal abnormalities and severe dysfunction of PLM mechanosensory neurons without cell death
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence for apoptotic cell death in Huntington disease and excitotoxic animal models.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms of apoptosis by c-Myc
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanism of transcriptional activation by Sp1: evidence for coactivators
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the full-length huntingtin- interacting protein p231HBP/HYPB as a DNA-binding factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential loss of striatal projection neurons in Huntington disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Wild-type huntingtin protects from apoptosis upstream of caspase-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal distribution in the putamen in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Quantitative analysis of morphological features in Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-8 is required for cell death induced by expanded polyglutamine repeats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Axonal transport of N-terminal huntingtin suggests early pathology of corticostriatal projections in Huntington disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and the nervous system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intraneuronal aggregate formation and cell death after viral expression of expanded polyglutamine tracts in the adult rat brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reduction of Purkinje cell pathology in SCA1 transgenic mice by p53 deletion.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuronal death in cultured murine cortical cells is induced by inhibition of GAPDH and triosephosphate isomerase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington's disease intranuclear inclusions contain truncated, ubiquitinated huntingtin protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The selective vulnerability of nerve cells in Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ataxin-1 with an expanded glutamine tract alters nuclear matrix-associated structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Causes of death in patients with Huntington's disease and in unaffected first degree relatives
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
DNA end labeling (TUNEL) in Huntington's disease and other neuropathological conditions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Nonapoptotic neurodegeneration in a transgenic mouse model of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The mitochondrial toxin 3-nitropropionic acid induces differential expression patterns of apoptosis-related markers in rat striatum
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntington disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neuropathological classification of Huntington's disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase activation during apoptotic cell death induced by expanded polyglutamine in N2a cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
HIP-I: a huntingtin interacting protein isolated by the yeast two-hybrid system
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibiting caspase cleavage of huntingtin reduces toxicity and aggregate formation in neuronal and nonneuronal cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Early phenotypes that presage late-onset neurodegenerative disease allow testing of modifiers in Hdh CAG knock-in mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0278-5846%2803%2900021-6
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0278-5846(03)00021-6
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
PubMed publication ID
12657365
1 reference
stated in
Europe PubMed Central
PubMed publication ID
12657365
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12657365%20AND%20SRC:MED&resulttype=core&format=json
retrieved
1 November 2019
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