(Q28291186)

Targeting EGFR and HER-2 receptor tyrosine kinases for cancer drug discovery and development

21 January 2018

1 reference

EGFR antagonists in cancer treatment

21 January 2018

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The biology of vascular endothelial growth factors.

21 January 2018

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VEGF-targeted therapy: mechanisms of anti-tumour activity.

21 January 2018

1 reference

Cellular signaling by fibroblast growth factor receptors

21 January 2018

1 reference

The FGF family: biology, pathophysiology and therapy

21 January 2018

1 reference

Anaplastic lymphoma kinase proteins in growth control and cancer

21 January 2018

1 reference

Anaplastic lymphoma kinase inhibition in non-small-cell lung cancer

21 January 2018

1 reference

RET tyrosine kinase signaling in development and cancer

21 January 2018

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Development of RET kinase inhibitors for targeted cancer therapy

21 January 2018

1 reference

Mechanisms of disease: Oncogene addiction--a rationale for molecular targeting in cancer therapy

21 January 2018

1 reference

Targeting cancer with small molecule kinase inhibitors

21 January 2018

1 reference

Combined targeting of EGFR-dependent and VEGF-dependent pathways: rationale, preclinical studies and clinical applications

21 January 2018

1 reference

Receptor tyrosine kinases and targeted cancer therapeutics

21 January 2018

1 reference

ErbB family receptor inhibitors as therapeutic agents in breast cancer: current status and future clinical perspective

21 January 2018

1 reference

Dysregulation of stem cell signaling network due to germline mutation, SNP, Helicobacter pylori infection, epigenetic change and genetic alteration in gastric cancer

21 January 2018

1 reference

Epigenetic regulation of WNT signaling in chronic lymphocytic leukemia.

21 January 2018

1 reference

Role of epigenomics in ovarian and endometrial cancers

21 January 2018

1 reference

Anti-VEGF and beyond: shaping a new generation of anti-angiogenic therapies for cancer

21 January 2018

1 reference

A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

21 January 2018

1 reference

Heparanase and syndecan-1 interplay orchestrates fibroblast growth factor-2-induced epithelial-mesenchymal transition in renal tubular cells

21 January 2018

1 reference

Fibroblast growth factor signaling in tumorigenesis

21 January 2018

1 reference

Fibroblast growth factor signalling: from development to cancer

21 January 2018

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Targeting mutant fibroblast growth factor receptors in cancer

21 January 2018

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FGF receptor inhibitors: role in cancer therapy

21 January 2018

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Asymmetric tyrosine kinase arrangements in activation or autophosphorylation of receptor tyrosine kinases

21 January 2018

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Mechanisms underlying differential responses to FGF signaling

21 January 2018

1 reference

Differential phosphoproteomics of fibroblast growth factor signaling: identification of Src family kinase-mediated phosphorylation events

21 January 2018

1 reference

Protein partners in the life history of activated fibroblast growth factor receptors

21 January 2018

1 reference

Network of WNT and other regulatory signaling cascades in pluripotent stem cells and cancer stem cells

21 January 2018

1 reference

Neural tube derived Wnt signals cooperate with FGF signaling in the formation and differentiation of the trigeminal placodes

21 January 2018

1 reference

FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia

21 January 2018

1 reference

The role of Notch signaling pathway in epithelial-mesenchymal transition (EMT) during development and tumor aggressiveness

21 January 2018

1 reference

Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer

21 January 2018

1 reference

Differentiation pathways in carcinogenesis and in chemo- and radioresistance

21 January 2018

1 reference

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

21 January 2018

1 reference

Tumorigenesis by mouse mammary tumor virus: Proviral activation of a cellular gene in the common integration region int-2

21 January 2018

1 reference

Insertional mutagenesis identifies a member of the Wnt gene family as a candidate oncogene in the mammary epithelium of int-2/Fgf-3 transgenic mice

21 January 2018

1 reference

Fibroblast growth factor receptor signaling dramatically accelerates tumorigenesis and enhances oncoprotein translation in the mouse mammary tumor virus-Wnt-1 mouse model of breast cancer

21 January 2018

1 reference

Insertional mutagenesis identifies multiple networks of cooperating genes driving intestinal tumorigenesis

21 January 2018

1 reference

Cross-talk of WNT and FGF signaling pathways at GSK3beta to regulate beta-catenin and SNAIL signaling cascades

21 January 2018

1 reference

WNT signaling in stem cell biology and regenerative medicine

21 January 2018

1 reference

Inhibition of adipogenesis by Wnt signaling

21 January 2018

1 reference

WNT signaling pathway and stem cell signaling network

21 January 2018

1 reference

A Wnt survival guide: from flies to human disease.

21 January 2018

1 reference

Physiological inhibitors of Wnt signaling

21 January 2018

1 reference

Mining the Wnt pathway for cancer therapeutics

21 January 2018

1 reference

The Wnt/beta-catenin pathway in adrenocortical development and cancer

21 January 2018

1 reference

Structural diversity of G protein-coupled receptors and significance for drug discovery

21 January 2018

1 reference

Antisera induced by infusions of autologous Ad-CD154-leukemia B cells identify ROR1 as an oncofetal antigen and receptor for Wnt5a

21 January 2018

1 reference

Wnt/Planar cell polarity signaling: a new paradigm for cancer therapy

21 January 2018

1 reference

Wnt3a stimulation elicits G-protein-coupled receptor properties of mammalian Frizzled proteins.

21 January 2018

1 reference

FGF-20 and DKK1 are transcriptional targets of beta-catenin and FGF-20 is implicated in cancer and development

21 January 2018

1 reference

FGF-1 and FGF-2 modulate the E-cadherin/catenin system in pancreatic adenocarcinoma cell lines

21 January 2018

1 reference

Balancing cell adhesion and Wnt signaling, the key role of beta-catenin

21 January 2018

1 reference

Inhibition of fibroblast growth factor 19 reduces tumor growth by modulating beta-catenin signaling

21 January 2018

1 reference

Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6.

21 January 2018

1 reference

Cell cycle control of wnt receptor activation

21 January 2018

1 reference

FGF/MAPK/Ets signaling renders pigment cell precursors competent to respond to Wnt signal by directly controlling Ci-Tcf transcription.

21 January 2018

1 reference

Polarized endocytosis of the keratinocyte growth factor receptor in migrating cells: role of SRC-signaling and cortactin

21 January 2018

1 reference

Epithelial-mesenchymal transitions in tumour progression

21 January 2018

1 reference

Evolutionary history of the Snail/Scratch superfamily.

21 January 2018

1 reference

Mechanisms of disease: epithelial-mesenchymal transition--does cellular plasticity fuel neoplastic progression?

21 January 2018

1 reference

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

21 January 2018

1 reference

Genetic heterogeneity of Saethre-Chotzen syndrome, due to TWIST and FGFR mutations.

21 January 2018

1 reference

Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: a potential therapeutic target in colorectal cancer.

21 January 2018

1 reference

Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: tumor budding as oncotarget

21 January 2018

1 reference

Molecular requirements for epithelial-mesenchymal transition during tumor progression

21 January 2018

1 reference

TGF-beta and epithelial-to-mesenchymal transitions

21 January 2018

1 reference

Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activation

21 January 2018

1 reference

Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes.

21 January 2018

1 reference

Wnt5a is required for proper mammary gland development and TGF-beta-mediated inhibition of ductal growth

21 January 2018

1 reference

Transcriptional mechanisms of WNT5A based on NF-kappaB, Hedgehog, TGFbeta, and Notch signaling cascades

21 January 2018

1 reference

Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture

21 January 2018

1 reference

Contribution of epithelial-to-mesenchymal transition and cancer stem cells to pancreatic cancer progression

21 January 2018

1 reference

The Wnt5A/protein kinase C pathway mediates motility in melanoma cells via the inhibition of metastasis suppressors and initiation of an epithelial to mesenchymal transition.

21 January 2018

1 reference

WNT5A--target of CUTL1 and potent modulator of tumor cell migration and invasion in pancreatic cancer

21 January 2018

1 reference

Wnt5a as an effector of TGFβ in mammary development and cancer

21 January 2018

1 reference

Genome-wide association study identifies novel breast cancer susceptibility loci

21 January 2018

1 reference

Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases

21 January 2018

1 reference

FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation

21 January 2018

1 reference

Genetic susceptibility loci for breast cancer by estrogen receptor status

21 January 2018

1 reference

Allele-specific regulation of FGFR2 expression is cell type-dependent and may increase breast cancer risk through a paracrine stimulus involving FGF10

21 January 2018

1 reference

Common genetic variants and modification of penetrance of BRCA2-associated breast cancer

21 January 2018

1 reference

Risk of aggressive breast cancer in women of Han nationality carrying TGFB1 rs1982073 C allele and FGFR2 rs1219648 G allele in North China.

21 January 2018

1 reference

FGFR2 genotype and risk of radiation-associated breast cancer in Hodgkin lymphoma

21 January 2018

1 reference

Genetic alterations of FGF receptors: an emerging field in clinical cancer diagnostics and therapeutics

21 January 2018

1 reference

Frequent and focal FGFR1 amplification associates with therapeutically tractable FGFR1 dependency in squamous cell lung cancer.

21 January 2018

1 reference

A comprehensive survey of genomic alterations in gastric cancer reveals systematic patterns of molecular exclusivity and co-occurrence among distinct therapeutic targets

21 January 2018

1 reference

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

21 January 2018

1 reference

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium

21 January 2018

1 reference

Cancer genetics and genomics of human FOX family genes

21 January 2018

1 reference

8p11 myeloproliferative syndrome: a review.

21 January 2018

1 reference

FOXO1-FGFR1 fusion and amplification in a solid variant of alveolar rhabdomyosarcoma

21 January 2018

1 reference

Targeting FGFR3 in multiple myeloma: inhibition of t(4;14)-positive cells by SU5402 and PD173074.

21 January 2018

1 reference

Transforming fusions of FGFR and TACC genes in human glioblastoma

21 January 2018

1 reference

Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome

21 January 2018

1 reference

Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2

21 January 2018

1 reference

Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome

21 January 2018

1 reference

Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes

21 January 2018

1 reference

Fibroblast growth factor receptor 2 mutations in Beare-Stevenson cutis gyrata syndrome

21 January 2018

1 reference

Drug-sensitive FGFR2 mutations in endometrial carcinoma

21 January 2018

1 reference

FGFR2 point mutations in 466 endometrioid endometrial tumors: relationship with MSI, KRAS, PIK3CA, CTNNB1 mutations and clinicopathological features

21 January 2018

1 reference

Loss-of-function fibroblast growth factor receptor-2 mutations in melanoma

21 January 2018

1 reference

Prospective study of FGFR3 mutations as a prognostic factor in nonmuscle invasive urothelial bladder carcinomas.

21 January 2018

1 reference

FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies

21 January 2018

1 reference

Genetic basis of potential therapeutic strategies for craniosynostosis

21 January 2018

1 reference

21 January 2018

1 reference

The role of senescence and prosurvival signaling in controlling the oncogenic activity of FGFR2 mutants associated with cancer and birth defects

21 January 2018

1 reference

The role of fibroblast growth factors in tumor growth

21 January 2018

1 reference

Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death.

21 January 2018

1 reference

Targeting fibroblast-growth-factor-receptor-dependent signaling for cancer therapy.

21 January 2018

1 reference

Antiglioma effects of a new, low molecular mass, inhibitor of fibroblast growth factor

21 January 2018

1 reference

Anti-angiogenic activity of selected receptor tyrosine kinase inhibitors, PD166285 and PD173074: implications for combination treatment with photodynamic therapy

21 January 2018

1 reference

CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.

21 January 2018

1 reference

Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome.

21 January 2018

1 reference

Activity of the fibroblast growth factor receptor inhibitors dovitinib (TKI258) and NVP-BGJ398 in human endometrial cancer cells

21 January 2018

1 reference

Orally active anti-proliferation agents: novel diphenylamine derivatives as FGF-R2 autophosphorylation inhibitors

21 January 2018

1 reference

A novel molecular targeting compound as K-samII/FGF-R2 phosphorylation inhibitor, Ki23057, for Scirrhous gastric cancer

21 January 2018

1 reference

E7080, a novel inhibitor that targets multiple kinases, has potent antitumor activities against stem cell factor producing human small cell lung cancer H146, based on angiogenesis inhibition

21 January 2018

1 reference

Brivanib alaninate, a dual inhibitor of vascular endothelial growth factor receptor and fibroblast growth factor receptor tyrosine kinases, induces growth inhibition in mouse models of human hepatocellular carcinoma

21 January 2018

1 reference

BIBF 1120: triple angiokinase inhibitor with sustained receptor blockade and good antitumor efficacy

21 January 2018

1 reference

AP24534, a pan-BCR-ABL inhibitor for chronic myeloid leukemia, potently inhibits the T315I mutant and overcomes mutation-based resistance

21 January 2018

1 reference

Ponatinib (AP24534), a multitargeted pan-FGFR inhibitor with activity in multiple FGFR-amplified or mutated cancer models

21 January 2018

1 reference

MK-2461, a novel multitargeted kinase inhibitor, preferentially inhibits the activated c-Met receptor

21 January 2018

1 reference

E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models

21 January 2018

1 reference

AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family

21 January 2018

1 reference

N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity

21 January 2018

1 reference

A FGFR2 inhibitor, Ki23057, enhances the chemosensitivity of drug-resistant gastric cancer cells

21 January 2018

1 reference

Beyond VEGF: inhibition of the fibroblast growth factor pathway and antiangiogenesis

21 January 2018

1 reference

Targeting FGF19 inhibits tumor growth in colon cancer xenograft and FGF19 transgenic hepatocellular carcinoma models.

21 January 2018

1 reference

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

21 January 2018

1 reference

Monoclonal antibodies to fibroblast growth factor receptor 2 effectively inhibit growth of gastric tumor xenografts

21 January 2018

1 reference

Advances in microRNAs: implications for gene therapists

21 January 2018

1 reference

miRNAs and regulation of cell signaling.

21 January 2018

1 reference

MicroRNA expression signatures of bladder cancer revealed by deep sequencing

21 January 2018

1 reference

Obesity short-circuits stemness gene network in human adipose multipotent stem cells.

21 January 2018

1 reference

Functional analysis of microRNAs in human hepatocellular cancer stem cells

21 January 2018

1 reference

Variation in the miRNA-433 binding site of FGF20 confers risk for Parkinson disease by overexpression of alpha-synuclein

21 January 2018

1 reference

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts

21 January 2018

1 reference

Systematic detection of putative tumor suppressor genes through the combined use of exome and transcriptome sequencing

21 January 2018

1 reference

Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine

21 January 2018

1 reference

RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis

21 January 2018

1 reference

MiR-125b, a MicroRNA Downregulated in Psoriasis, Modulates Keratinocyte Proliferation by Targeting FGFR2

21 January 2018

1 reference

FGFR2 alterations in endometrial carcinoma

21 January 2018

1 reference

The expanding world of small RNAs

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/MED.21288

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

PubMed publication ID

23696246

1 reference

Consolidated OpenCitations Corpus – April 2017