(Q28291558)

24 June 2017

Structure-based design and mechanisms of allosteric inhibitors for mitochondrial branched-chain α-ketoacid dehydrogenase kinase (English)

1 reference

24 June 2017

1 reference

9

Philippe M Campeau

1 reference

24 June 2017

Shih-Chia Tso

1

1 reference

24 June 2017

Xiangbing Qi

2

1 reference

24 June 2017

Wen-Jun Gui

3

1 reference

24 June 2017

Jacinta L Chuang

4

1 reference

24 June 2017

Lorraine K Morlock

5

1 reference

24 June 2017

Amy L Wallace

6

1 reference

24 June 2017

Kamran Ahmed

7

1 reference

24 June 2017

Sunil Laxman

8

1 reference

24 June 2017

Brendan H Lee

10

1 reference

24 June 2017

Susan M Hutson

11

1 reference

24 June 2017

Benjamin P Tu

12

1 reference

24 June 2017

Noelle S Williams

13

1 reference

24 June 2017

Uttam K Tambar

14

1 reference

24 June 2017

R Max Wynn

15

1 reference

24 June 2017

David T Chuang

16

1 reference

24 June 2017

language of work or name

English

0 references

publication date

28 May 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 June 2017

1 reference

24 June 2017

110

1 reference

24 June 2017

24

1 reference

24 June 2017

9728-9733

1 reference

Interplay between lipids and branched-chain amino acids in development of insulin resistance

24 June 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Structural and Biochemical Characterization of Human Mitochondrial Branched-chain -Ketoacid Dehydrogenase Phosphatase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Clinical and experimental applications of sodium phenylbutyrate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Crystal structure of pyruvate dehydrogenase kinase 3 bound to lipoyl domain 2 of human pyruvate dehydrogenase complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Structure of rat BCKD kinase: Nucleotide-induced domain communication in a mitochondrial protein kinase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Branched-chain amino acid metabolism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Expression and characterization of branched-chain alpha-ketoacid dehydrogenase kinase from the rat. Is it a histidine-protein kinase?

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Metabolite profiles and the risk of developing diabetes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Branched-chain and aromatic amino acids are predictors of insulin resistance in young adults

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Urinary phenylacetylglutamine as dosing biomarker for patients with urea cycle disorders.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Tissue-specific and nutrient regulation of the branched-chain α-keto acid dehydrogenase phosphatase, protein phosphatase 2Cm (PP2Cm).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Hypothalamic leucine metabolism regulates liver glucose production

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Catabolism of branched-chain amino acids in heart failure: insights from genetic models.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Phenylbutyrate therapy for maple syrup urine disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Protein phosphatase 2Cm is a critical regulator of branched-chain amino acid catabolism in mice and cultured cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Mechanisms responsible for regulation of branched-chain amino acid catabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Utility of in vitro drug metabolism data in predicting in vivo metabolic clearance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Regulation of branched-chain amino acid catabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Alteration in gene expression of branched-chain keto acid dehydrogenase kinase but not in gene expression of its substrate in the liver of clofibrate-treated rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Enzymic determination of branched-chain amino acids and 2-oxoacids in rat tissues. Transfer of 2-oxoacids from skeletal muscle to liver in vivo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Inhibition of branched-chain alpha-keto acid dehydrogenase kinase by alpha-chloroisocaproate

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Effects of clofibric acid on the activity and activity state of the hepatic branched-chain 2-oxo acid dehydrogenase complex

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Branched-chain amino acid oxidation by isolated rat tissue preparations

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Transaminase of branched chain amino acids. I. Branched chain amino acids-alpha-ketoglutarate transaminase.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3683707

Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1303220110

Regulation of branched-chain amino acid catabolism in rat models for spontaneous type 2 diabetes mellitus

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.1303220110

Clofibrate-induced reduction of plasma branched-chain amino acid concentrations impairs glucose tolerance in rats

21 January 2018

1 reference

12 December 2020

Diagnosis and mutational analysis of maple syrup urine disease using cell cultures

1 reference

12 December 2020

Inhibition of branched chain alpha-ketoacid dehydrogenase kinase activity by alpha-chloroisocaproate

1 reference

12 December 2020

Regulation of branched-chain alpha-ketoacid dehydrogenase kinase

1 reference

12 December 2020

Clofibric acid, phenylpyruvate, and dichloroacetate inhibition of branched-chain alpha-ketoacid dehydrogenase kinase in vitro and in perfused rat heart

1 reference

12 December 2020

Subcellular distribution of branched-chain aminotransferase activity in rat tissues

1 reference

12 December 2020

Regulation by induction of branched-chain 2-oxo acid dehydrogenase complex in clofibrate-fed rat liver

1 reference

12 December 2020

Effect of alpha-ketoacid dehydrogenase phosphorylation on branched-chain amino acid metabolism in muscle

1 reference

12 December 2020

Site-directed mutagenesis of phosphorylation sites of the branched chain alpha-ketoacid dehydrogenase complex

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1303220110

1 reference

release_zwqqs44wojc7bisvg3scvwq3uq

24 June 2017

0 references

0 references

OpenCitations bibliographic resource ID

4645412

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference