(Q28334584)

English

HCT 116

cell line

HCT-116
HCT.116
HCT_116
HCT116
CoCL2

In more languages

Statements

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Cellosaurus release 36

4 December 2020

cancer cell line

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autologous cell line

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described by source

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines.

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4 December 2020

Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines.

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4 December 2020

Selective modifications of cellular proteins in intratumoral subpopulations of human colonic carcinoma cells.

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4 December 2020

Heterogeneity of human colon carcinoma.

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Heterogeneity of malignant cells from a human colonic carcinoma.

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4 December 2020

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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4 December 2020

Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.

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4 December 2020

BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.

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4 December 2020

Beta-catenin mutations in cell lines established from human colorectal cancers.

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4 December 2020

Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

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4 December 2020

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

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4 December 2020

Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.

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4 December 2020

Systematic variation in gene expression patterns in human cancer cell lines

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4 December 2020

APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

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4 December 2020

Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

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4 December 2020

Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.

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4 December 2020

Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.

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4 December 2020

Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.

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4 December 2020

Assembly of microarrays for genome-wide measurement of DNA copy number.

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4 December 2020

Mutations of the BRAF gene in human cancer

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Spectral karyotype analysis of colon cancer cell lines of the tumor suppressor and mutator pathway.

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Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines.

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Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues.

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

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High resolution array-CGH analysis of single cells.

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Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis.

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4 December 2020

Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

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4 December 2020

Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.

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4 December 2020

DNA fingerprinting of the NCI-60 cell line panel.

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4 December 2020

Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines.

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4 December 2020

A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

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4 December 2020

Genomic and biological characterization of exon 4 KRAS mutations in human cancer

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4 December 2020

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency.

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4 December 2020

Therapeutic reactivation of mutant p53 protein by quinazoline derivatives.

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4 December 2020

JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs

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4 December 2020

Identification of cancer cell-line origins using fluorescence image-based phenomic screening.

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4 December 2020

The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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4 December 2020

Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

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4 December 2020

Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

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4 December 2020

A novel approach for characterizing microsatellite instability in cancer cells.

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4 December 2020

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology.

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4 December 2020

Global proteome analysis of the NCI-60 cell line panel.

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4 December 2020

Epigenetic and genetic features of 24 colon cancer cell lines

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4 December 2020

The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

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4 December 2020

High resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMiner

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4 December 2020

Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer.

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A comprehensive transcriptional portrait of human cancer cell lines.

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Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

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4 December 2020

Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.

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4 December 2020

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets.

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4 December 2020

Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies.

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4 December 2020

Metabolic signatures differentiate ovarian from colon cancer cell lines.

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4 December 2020

Global metabolite profiling of human colorectal cancer xenografts in mice using HPLC-MS/MS.

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4 December 2020

N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.

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4 December 2020

Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR

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4 December 2020

A landscape of pharmacogenomic interactions in cancer.

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4 December 2020

A map of mobile DNA insertions in the NCI-60 human cancer cell panel.

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4 December 2020

A novel RNA sequencing data analysis method for cell line authentication.

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4 December 2020

Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

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4 December 2020

Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies.

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4 December 2020

Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

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4 December 2020

Pharmacoproteomic characterisation of human colon and rectal cancer.

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4 December 2020

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay.

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4 December 2020

HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.

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4 December 2020

CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma

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4 December 2020

Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53

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4 December 2020

Mutations truncating the EP300 acetylase in human cancers

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4 December 2020

Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

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4 December 2020

HLA class I and II genotype of the NCI-60 cell lines

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4 December 2020

p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.

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4 December 2020

Signatures of mutation and selection in the cancer genome.

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4 December 2020

Acquired irinotecan resistance is accompanied by stable modifications of cell cycle dynamics independent of MSI status.

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4 December 2020

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines

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4 December 2020

An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes.

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4 December 2020

Differential Effector Engagement by Oncogenic KRAS.

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4 December 2020

An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines

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4 December 2020

Next-generation characterization of the Cancer Cell Line Encyclopedia

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4 December 2020

Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

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4 December 2020

Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer

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4 December 2020

Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance.

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4 December 2020

In vitro characterization of spheres derived from colorectal cancer cell lines.

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4 December 2020

Comparison of Different Colorectal Cancer With Liver Metastases Models Using Six Colorectal Cancer Cell Lines

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4 December 2020

Mutations and altered expression of p16INK4 in human cancer.

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4 December 2020

APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.

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http://purl.obolibrary.org/obo/BTO_0001109

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http://purl.obolibrary.org/obo/EFO_0002824

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http://purl.obolibrary.org/obo/CLO_0003665

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Commons category

HCT116 cells

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established from medical condition

colon carcinoma

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Cellosaurus release 36

4 December 2020

Identifiers

MeSH descriptor ID

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Cell Line Ontology ID

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Google Knowledge Graph ID

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Sitelinks

Wikipedia(2 entries)

enwiki HCT116 cells
zhwiki HCT 166

Wikibooks(0 entries)

Wikinews(0 entries)

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Multilingual sites(1 entry)

commonswiki Category:HCT116 cells

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