(Q28334584)

English

HCT 116

cell line

HCT-116
HCT.116
HCT_116
HCT116
HCT116wt
CoCL2

In more languages

Statements

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Cellosaurus release 44

10 January 2023

cancer cell line

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autologous cell line

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described by source

Feasibility of a high-flux anticancer drug screen using a diverse panel of cultured human tumor cell lines.

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10 January 2023

Determination of the levels of urokinase and its receptor in human colon carcinoma cell lines.

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Selective modifications of cellular proteins in intratumoral subpopulations of human colonic carcinoma cells.

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Heterogeneity of human colon carcinoma.

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Heterogeneity of malignant cells from a human colonic carcinoma.

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

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Inverse correlation between RER+ status and p53 mutation in colorectal cancer cell lines.

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BAT-26, an indicator of the replication error phenotype in colorectal cancers and cell lines.

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Beta-catenin mutations in cell lines established from human colorectal cancers

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Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.

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Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

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Mutations in hMSH6 alone are not sufficient to cause the microsatellite instability in colorectal cancer cell lines.

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Systematic variation in gene expression patterns in human cancer cell lines

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APC mutations in sporadic colorectal tumors: A mutational "hotspot" and interdependence of the "two hits"

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Spectral karyotyping suggests additional subsets of colorectal cancers characterized by pattern of chromosome rearrangement.

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Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.

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Comprehensive galectin fingerprinting in a panel of 61 human tumor cell lines by RT-PCR and its implications for diagnostic and therapeutic procedures.

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Extensive characterization of genetic alterations in a series of human colorectal cancer cell lines.

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Assembly of microarrays for genome-wide measurement of DNA copy number

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Mutations of the BRAF gene in human cancer

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Spectral karyotype analysis of colon cancer cell lines of the tumor suppressor and mutator pathway.

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Analysis of P53 mutations and their expression in 56 colorectal cancer cell lines

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Identification by Real-time PCR of 13 mature microRNAs differentially expressed in colorectal cancer and non-tumoral tissues

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Mutation analysis of 24 known cancer genes in the NCI-60 cell line set.

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High resolution array-CGH analysis of single cells

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Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis.

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Cell growth, global phosphotyrosine elevation, and c-Met phosphorylation through Src family kinases in colorectal cancer cells

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10 January 2023

Altered expression of cell proliferation-related and interferon-stimulated genes in colon cancer cells resistant to SN38.

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DNA fingerprinting of the NCI-60 cell line panel

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Definitive molecular cytogenetic characterization of 15 colorectal cancer cell lines

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A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers

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10 January 2023

Genomic and biological characterization of exon 4 KRAS mutations in human cancer

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10 January 2023

5-Fluorouracil response in a large panel of colorectal cancer cell lines is associated with mismatch repair deficiency

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10 January 2023

Therapeutic reactivation of mutant p53 protein by quinazoline derivatives.

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10 January 2023

JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs

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Identification of cancer cell-line origins using fluorescence image-based phenomic screening

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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity

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Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation

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Subtypes of primary colorectal tumors correlate with response to targeted treatment in colorectal cell lines

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A novel approach for characterizing microsatellite instability in cancer cells

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10 January 2023

The exomes of the NCI-60 panel: a genomic resource for cancer biology and systems pharmacology

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Global proteome analysis of the NCI-60 cell line panel

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Epigenetic and genetic features of 24 colon cancer cell lines

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The metabolic demands of cancer cells are coupled to their size and protein synthesis rates

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High resolution copy number variation data in the NCI-60 cancer cell lines from whole genome microarrays accessible through CellMiner

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Colorectal cancer cell lines are representative models of the main molecular subtypes of primary cancer

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A comprehensive transcriptional portrait of human cancer cell lines

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Mass Spectrometry of Human Leukocyte Antigen Class I Peptidomes Reveals Strong Effects of Protein Abundance and Turnover on Antigen Presentation

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Feasibility of label-free phosphoproteomics and application to base-line signaling of colorectal cancer cell lines.

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10 January 2023

The molecular landscape of colorectal cancer cell lines unveils clinically actionable kinase targets

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Parallel genome-scale loss of function screens in 216 cancer cell lines for the identification of context-specific genetic dependencies

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Metabolic signatures differentiate ovarian from colon cancer cell lines

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Global metabolite profiling of human colorectal cancer xenografts in mice using HPLC-MS/MS.

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N-glycosylation Profiling of Colorectal Cancer Cell Lines Reveals Association of Fucosylation with Differentiation and Caudal Type Homebox 1 (CDX1)/Villin mRNA Expression.

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Long non-coding RNA expression profiling in the NCI60 cancer cell line panel using high-throughput RT-qPCR

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A landscape of pharmacogenomic interactions in cancer.

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A map of mobile DNA insertions in the NCI-60 human cancer cell panel.

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A novel RNA sequencing data analysis method for cell line authentication

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Characterization of Human Cancer Cell Lines by Reverse-phase Protein Arrays

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Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies

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Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells.

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Pharmacoproteomic characterisation of human colon and rectal cancer.

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Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

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10 January 2023

HLA-A locus-restricted and tumor-specific CTLs in tumor-infiltrating lymphocytes of patients with non-small cell lung cancer.

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CD4+ hepatic cancer-specific cytotoxic T lymphocytes in patients with hepatocellular carcinoma

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Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53

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Mutations truncating the EP300 acetylase in human cancers

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Evidence of selection for clones having genetic inactivation of the activin A type II receptor (ACVR2) gene in gastrointestinal cancers.

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HLA class I and II genotype of the NCI-60 cell lines

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p53-defective tumors with a functional apoptosome-mediated pathway: a new therapeutic target.

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Signatures of mutation and selection in the cancer genome.

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Acquired irinotecan resistance is accompanied by stable modifications of cell cycle dynamics independent of MSI status.

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10 January 2023

A catalog of HLA type, HLA expression, and neo-epitope candidates in human cancer cell lines

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An Optimized Shotgun Strategy for the Rapid Generation of Comprehensive Human Proteomes

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Differential Effector Engagement by Oncogenic KRAS.

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An Interactive Resource to Probe Genetic Diversity and Estimated Ancestry in Cancer Cell Lines

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10 January 2023

Next-generation characterization of the Cancer Cell Line Encyclopedia

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Quantitative Proteomics of the Cancer Cell Line Encyclopedia.

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Increased mutation rate at the hprt locus accompanies microsatellite instability in colon cancer

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Redefining the relevance of established cancer cell lines to the study of mechanisms of clinical anti-cancer drug resistance

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In vitro characterization of spheres derived from colorectal cancer cell lines.

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Comparison of Different Colorectal Cancer With Liver Metastases Models Using Six Colorectal Cancer Cell Lines

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Mutations and altered expression of p16INK4 in human cancer.

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APC Mutations as a Potential Biomarker for Sensitivity to Tankyrase Inhibitors in Colorectal Cancer.

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10 January 2023

Single-molecule optical genome mapping of a human HapMap and a colorectal cancer cell line.

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Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition

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Variation in the extent of microsatellite instability in human cell lines with defects in different mismatch repair genes

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established from medical condition

colon carcinoma

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derived from organism type

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http://purl.obolibrary.org/obo/BTO_0001109

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http://purl.obolibrary.org/obo/EFO_0002824

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http://purl.obolibrary.org/obo/CLO_0003665

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Commons category

HCT116 cells

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Identifiers

MeSH descriptor ID

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Cell Line Ontology ID

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Google Knowledge Graph ID

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Sitelinks

Wikipedia(3 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(1 entry)

commonswiki Category:HCT116 cells

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