(Q28387182)

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A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos

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A protein kinase Cdelta-dependent protein kinase D pathway modulates ERK1/2 and JNK1/2 phosphorylation and Bim-associated apoptosis by asbestos (English)

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phosphorylation

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Brooke T. Mossman

6

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Brooke T Mossman

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author name string

Sylke A Buder-Hoffmann

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Arti Shukla

2

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Trisha F Barrett

3

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Maximilian B MacPherson

4

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Karen M Lounsbury

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publication date

February 2009

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The American Journal of Pathology

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174

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2

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449-59

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ERK1/2-dependent phosphorylation of BimEL promotes its rapid dissociation from Mcl-1 and Bcl-xL

1 reference

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20 March 2017

FKHRL1-mediated expression of Noxa and Bim induces apoptosis via the mitochondria in neuroblastoma cells

1 reference

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20 March 2017

TNF-alpha inhibits asbestos-induced cytotoxicity via a NF-kappaB-dependent pathway, a possible mechanism for asbestos-induced oncogenesis

1 reference

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20 March 2017

Oxidants and signaling by mitogen-activated protein kinases in lung epithelium

1 reference

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20 March 2017

Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis

1 reference

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20 March 2017

JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis

1 reference

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20 March 2017

Protein kinase D: an intracellular traffic regulator on the move

1 reference

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20 March 2017

SP600125, an anthrapyrazolone inhibitor of Jun N-terminal kinase

1 reference

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20 March 2017

Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases

1 reference

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20 March 2017

Increased phosphorylated extracellular signal-regulated kinase immunoreactivity associated with proliferative and morphologic lung alterations after chrysotile asbestos inhalation in mice

1 reference

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1 reference

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20 March 2017

The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

1 reference

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20 March 2017

Mechanisms in the Pathogenesis of Asbestosis and Silicosis

1 reference

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20 March 2017

Bim: a novel member of the Bcl-2 family that promotes apoptosis

1 reference

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20 March 2017

Role of extracellular signal-regulated protein kinases in apoptosis by asbestos and H2O2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

20 March 2017

Novel cell imaging techniques show induction of apoptosis and proliferation in mesothelial cells by asbestos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

20 March 2017

Asbestos induces nuclear factor kappa B (NF-kappa B) DNA-binding activity and NF-kappa B-dependent gene expression in tracheal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

20 March 2017

Increased proliferation of B cells and auto-immunity in mice lacking protein kinase Cdelta

1 reference

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20 March 2017

MAP kinase signalling pathways in cancer

1 reference

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7 April 2017

The Bcl2 family: regulators of the cellular life-or-death switch

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

7 April 2017

Anoikis, initiated by Mcl-1 degradation and Bim induction, is deregulated during oncogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

6-Hydroxydopamine induces mitochondrial ERK activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

BimS-induced apoptosis requires mitochondrial localization but not interaction with anti-apoptotic Bcl-2 proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Frequent loss of expression of the pro-apoptotic protein Bim in renal cell carcinoma: evidence for contribution to apoptosis resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

PKD at the crossroads of DAG and PKC signaling

1 reference

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29 September 2017

P53 mediates amosite asbestos-induced alveolar epithelial cell mitochondria-regulated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Bim is a direct target of a neuronal E2F-dependent apoptotic pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Protein kinase D signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Protein kinase Cdelta selectively regulates protein kinase D-dependent activation of NF-kappaB in oxidative stress signaling

1 reference

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29 September 2017

Src-dependent ERK5 and Src/EGFR-dependent ERK1/2 activation is required for cell proliferation by asbestos

1 reference

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29 September 2017

Role of Bim in the survival pathway induced by Raf in epithelial cells

1 reference

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29 September 2017

Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function.

1 reference

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29 September 2017

Multiple roles of oxidants in the pathogenesis of asbestos-induced diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Activation of the ERK1/2 signaling pathway promotes phosphorylation and proteasome-dependent degradation of the BH3-only protein, Bim.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Asbestos-induced apoptosis is protein kinase C delta-dependent

1 reference

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29 September 2017

Activation of ERK1/2 by deltaRaf-1:ER* represses Bim expression independently of the JNK or PI3K pathways

1 reference

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29 September 2017

Persistent localization of activated extracellular signal-regulated kinases (ERK1/2) is epithelial cell-specific in an inhalation model of asbestosis

1 reference

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29 September 2017

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1 reference

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29 September 2017

Different accumulation of activated extracellular signal-regulated kinases (ERK 1/2) and role in cell-cycle alterations by epidermal growth factor, hydrogen peroxide, or asbestos in pulmonary epithelial cells

1 reference

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29 September 2017

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1 reference

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29 September 2017

Persistent induction of c-fos and c-jun expression by asbestos

1 reference

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29 September 2017

Molecular cloning and characterization of protein kinase D: a target for diacylglycerol and phorbol esters with a distinctive catalytic domain

1 reference

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29 September 2017

Protein kinase C involvement in apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

29 September 2017

Hydrolysis of inositol phospholipids precedes cellular proliferation in asbestos-stimulated tracheobronchial epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

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1 reference

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Protein kinase C mu selectively activates the mitogen-activated protein kinase (MAPK) p42 pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

2 June 2018

Oxidative stress induces protein kinase D activation in intact cells. Involvement of Src and dependence on protein kinase C.

1 reference

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2 June 2018

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1 reference

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Mouse lung epithelial cell lines--tools for the study of differentiation and the neoplastic phenotype

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2 June 2018

Inhibition of lung injury, inflammation, and interstitial pulmonary fibrosis by polyethylene glycol-conjugated catalase in a rapid inhalation model of asbestosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

2 June 2018

Asbestos: scientific developments and implications for public policy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

2 June 2018

The duration of nuclear extracellular signal-regulated kinase 1 and 2 signaling during cell cycle reentry distinguishes proliferation from apoptosis in response to asbestos

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

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Activation loop phosphorylation controls protein kinase D-dependent activation of nuclear factor kappaB.

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Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: identification of two cleavage sites by microsequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

27 November 2018

Hydrogen peroxide signaling through tumor necrosis factor receptor 1 leads to selective activation of c-Jun N-terminal kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

27 November 2018

JNK-mediated BIM phosphorylation potentiates BAX-dependent apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

27 November 2018

Protein kinase Cmu downregulation of tumor-necrosis-factor-induced apoptosis correlates with enhanced expression of nuclear-factor-kappaB-dependent protective genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630554

27 November 2018

Loss of protein kinase C function induces an apoptotic response

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

12 December 2020

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Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

12 December 2020

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inferred from PubMed ID database lookup

Chronic Protein Kinase B (PKB/c-akt) Activation Leads to Apoptosis Induced by Oxidative Stress-Mediated Foxo3a Transcriptional Up-regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/19116364

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inferred from PubMed ID database lookup

Airway Epithelial NF- B Activation Modulates Asbestos-Induced Inflammation and Mucin Production In Vivo

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Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

12 December 2020

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Proteolytic cleavage and activation of protein kinase C [micro] by caspase-3 in the apoptotic response of cells to 1-beta -D-arabinofuranosylcytosine and other genotoxic agents

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

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inferred from PubMed ID database lookup

Asbestos and cigarette smoke cause increased DNA strand breaks and necrosis in bronchiolar epithelial cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

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PKCμ prevents CD95-mediated apoptosis and enhances proliferation in pancreatic tumour cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19116364

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1 reference

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Identifiers

10.2353/AJPATH.2009.080180

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