(Q28390612)

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The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells

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The ETS family transcription factor ELK-1 regulates induction of the cell cycle-regulatory gene p21(Waf1/Cip1) and the BAX gene in sodium arsenite-exposed human keratinocyte HaCaT cells (English)

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author name string

Soon Young Shin

1

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Chang Gun Kim

2

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Yoongho Lim

3

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Young Han Lee

4

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publication date

29 July 2011

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Journal of Biological Chemistry

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286

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30

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26860-72

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p21WAF1 expression induced by MEK/ERK pathway activation or inhibition correlates with growth arrest, myogenic differentiation and onco-phenotype reversal in rhabdomyosarcoma cells.

1 reference

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20 March 2017

Arsenite induces a cell stress-response gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein

1 reference

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20 March 2017

Transcriptional regulation of the cytosolic chaperonin theta subunit gene, Cctq, by Ets domain transcription factors Elk-1, Sap-1a, and Net in the absence of serum response factor

1 reference

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20 March 2017

The molecular mechanisms of arsenic-induced cell transformation and apoptosis

1 reference

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c-Fos oncogene regulator Elk-1 interacts with BRCA1 splice variants BRCA1a/1b and enhances BRCA1a/1b-mediated growth suppression in breast cancer cells

1 reference

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WAF1, a potential mediator of p53 tumor suppression

1 reference

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The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

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Ets-1 protects vascular smooth muscle cells from undergoing apoptosis by activating p21WAF1/Cip1: ETS-1 regulates basal and and inducible p21WAF1/Cip: ETS-1 regulates basal and inducible p21WAF1/Cip1 transcription via distinct cis-acting [...]

1 reference

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1 reference

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1 reference

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

1 reference

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1 reference

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1 reference

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Overlapping promoter targeting by Elk-1 and other divergent ETS-domain transcription factor family members

1 reference

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p21Cip1/WAF1 mediates cyclin B1 degradation in response to DNA damage

1 reference

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p21 Waf1/Cip1 expression by curcumin in U-87MG human glioma cells: role of early growth response-1 expression

1 reference

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A novel antioxidant 3-O-Caffeoyl-1-methylquinic acid enhances ultraviolet A-mediated apoptosis in immortalized HaCaT keratinocytes via Sp1-dependent transcriptional activation of p21(WAF1/Cip1).

1 reference

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Convergence of the SUMO and MAPK pathways on the ETS-domain transcription factor Elk-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

Cell cycle inhibition by sodium arsenite in primary embryonic rat midbrain neuroepithelial cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

As2O3-induced c-Src/EGFR/ERK signaling is via Sp1 binding sites to stimulate p21WAF1/CIP1 expression in human epidermoid carcinoma A431 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

PIASx acts as an Elk-1 coactivator by facilitating derepression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

p21-Mediated nuclear retention of cyclin B1-Cdk1 in response to genotoxic stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway

1 reference

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29 September 2017

Molecular mechanisms of arsenic carcinogenesis

1 reference

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Transcriptional activation of p21(waf1/cip1) by alkylphospholipids: role of the mitogen-activated protein kinase pathway in the transactivation of the human p21(waf1/cip1) promoter by Sp1.

1 reference

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29 September 2017

Ets ternary complex transcription factors

1 reference

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29 September 2017

New perspectives in arsenic-induced cell signal transduction

1 reference

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Permanent cell cycle exit in G2 phase after DNA damage in normal human fibroblasts.

1 reference

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Ternary complex factors: prime nuclear targets for mitogen-activated protein kinases

1 reference

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Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts

1 reference

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1 reference

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29 September 2017

The role of the cyclin-dependent kinase inhibitor p21 in apoptosis.

1 reference

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29 September 2017

The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects

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1 reference

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1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

Cell cycle arrest mediated by the MEK/mitogen-activated protein kinase pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

The transcription factors Elk-1 and serum response factor interact by direct protein-protein contacts mediated by a short region of Elk-1.

1 reference

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29 September 2017

Transforming growth factor beta induces the cyclin-dependent kinase inhibitor p21 through a p53-independent mechanism

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

29 September 2017

Involvement of p38 mitogen-activated protein kinase in the cell growth inhibition by sodium arsenite

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

2 June 2018

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

2 June 2018

p53 mutations in human immortalized epithelial cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

2 June 2018

The absorption of arsenic and its relation to carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

2 June 2018

Cyclin D1 induction through IkappaB kinase beta/nuclear factor-kappaB pathway is responsible for arsenite-induced increased cell cycle G1-S phase transition in human keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

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1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

Restoration of p53 tumor suppressor pathway in human cervical carcinoma cells by sodium arsenite.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

Involvement of reactive oxygen species in arsenite-induced downregulation of phospholipid hydroperoxide glutathione peroxidase in human epidermoid carcinoma A431 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

Tamoxifen-induced activation of p21Waf1/Cip1 gene transcription is mediated by Early Growth Response-1 protein through the JNK and p38 MAP kinase/Elk-1 cascades in MDA-MB-361 breast carcinoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

Transcription factor Egr-1 is essential for maximal matrix metalloproteinase-9 transcription by tumor necrosis factor alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

The zinc finger transcription factor Egr-1 is upregulated in arsenite-treated human keratinocytes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

p21Cip1 gene expression is modulated by Egr1: a novel regulatory mechanism involved in the resveratrol antiproliferative effect.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

EGR-1 forms a complex with YAP-1 and upregulates Bax expression in irradiated prostate carcinoma cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

Arsenic trioxide-induced transcriptional activation of stress genes and expression of related proteins in human liver carcinoma cells (HepG2).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3143646

27 November 2018

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1 reference

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27 November 2018

Uncoupling of S phase and mitosis induced by anticancer agents in cells lacking p21

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21 January 2018

Transcriptional Regulation of the p21(WAF1/CIP1)Gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.216721

21 January 2018

The conflicting roles of the cdk inhibitor p21(CIP1/WAF1) in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21642427

12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21642427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transactivation of the p21 promoter by BRCA1 splice variants in mammary epithelial cells: evidence for both common and distinct activities of wildtype and mutant forms

1 reference

https://pubmed.ncbi.nlm.nih.gov/21642427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

WAF1/CIP1 is induced in p53-mediated G1 arrest and apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21642427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of Erk, but not JNK, for arsenite-induced cell transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21642427

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1074/JBC.M110.216721

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