(Q28481010)

2

0 references

Reuben Shaw

3

0 references

Brendan D Manning

4

0 references

David J Kwiatkowski

Creative Commons Attribution 4.0 International

5

0 references

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

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volume

7

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issue

2

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page(s)

e31900

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copyright license

start time

21 February 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Comparative effectiveness and safety of medications for type 2 diabetes: an update including new drugs and 2-drug combinations

19 March 2017

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mTOR: from growth signal integration to cancer, diabetes and ageing

19 March 2017

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The TSC1-TSC2 complex: a molecular switchboard controlling cell growth

19 March 2017

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AMPK phosphorylation of raptor mediates a metabolic checkpoint

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Defining the role of mTOR in cancer

19 March 2017

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Rapamycin causes regression of astrocytomas in tuberous sclerosis complex

19 March 2017

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The LKB1 tumor suppressor negatively regulates mTOR signaling

19 March 2017

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TSC2 mediates cellular energy response to control cell growth and survival

19 March 2017

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Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background

19 March 2017

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Contraction-induced changes in acetyl-CoA carboxylase and 5'-AMP-activated kinase in skeletal muscle

19 March 2017

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The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin

19 March 2017

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19 March 2017

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mTOR links oncogenic signaling to tumor cell metabolism

7 April 2017

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Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis

29 September 2017

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Metformin prevents tobacco carcinogen--induced lung tumorigenesis

29 September 2017

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Proteasome inhibitor PS-341 (bortezomib) induces calpain-dependent IkappaB(alpha) degradation

29 September 2017

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The relationship among tumor architecture, pharmacokinetics, pharmacodynamics, and efficacy of bortezomib in mouse xenograft models.

29 September 2017

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Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis

29 September 2017

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Important role of the LKB1-AMPK pathway in suppressing tumorigenesis in PTEN-deficient mice

29 September 2017

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Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis

29 September 2017

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Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis

29 September 2017

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Bortezomib: efficacy comparisons in solid tumors and hematologic malignancies.

29 September 2017

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Tuberous sclerosis: a GAP at the crossroads of multiple signaling pathways

29 September 2017

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Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome

29 September 2017

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The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells.

29 September 2017

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Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models

29 September 2017

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Effects of rapamycin in the Eker rat model of tuberous sclerosis complex

21 January 2018

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Chemoprevention meets glucose control

21 January 2018

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