(Q28483928)

4

0 references

Manfred Jung

object named as

Manfred Jung

5

0 references

Anton Simeonov

6

object named as

Anton Simeonov

0 references

author name string

Silviya D Furdas

2

0 references

David J Maloney

Creative Commons CC0 License

3

0 references

language of work or name

English

0 references

publication date

2012

0 references

published in

PLOS One

0 references

volume

7

0 references

issue

9

0 references

page(s)

e45594

0 references

copyright license

start time

20 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

cites work

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1 reference

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Can the pharmaceutical industry reduce attrition rates?

19 March 2017

1 reference

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Protein binding: do we ever learn?

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447978

Brain tissue binding of drugs: evaluation and validation of solid supported porcine brain membrane vesicles (TRANSIL) as a novel high-throughput method

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447978

Drug-protein binding: a critical review of analytical tools

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447978

Plasma protein binding in drug discovery and development.

29 September 2017

1 reference

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A new homogeneous high-throughput screening assay for profiling compound activity on the human ether-a-go-go-related gene channel

29 September 2017

1 reference

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ADDME--Avoiding Drug Development Mistakes Early: central nervous system drug discovery perspective

29 September 2017

1 reference

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Advances in the integration of drug metabolism into the lead optimization paradigm

29 September 2017

1 reference

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Exploratory drug safety: a discovery strategy to reduce attrition in development

29 September 2017

1 reference

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A robotic platform for quantitative high-throughput screening

29 September 2017

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Recent advances in high throughput screening for ADME properties

29 September 2017

1 reference

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Determination of drug-serum protein interactions via fluorescence polarization measurements

29 September 2017

1 reference

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Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

29 September 2017

1 reference

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The extraordinary ligand binding properties of human serum albumin

29 September 2017

1 reference

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Predicting plasma protein binding of drugs--revisited.

29 September 2017

1 reference

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Drug-induced prolongation of the QT interval

29 September 2017

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HTS techniques to investigate the potential effects of compounds on cardiac ion channels at early-stages of drug discovery.

29 September 2017

1 reference

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Practical aspects of the ligand-binding and enzymatic properties of human serum albumin.

29 September 2017

1 reference

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High-throughput screening approaches for investigating drug metabolism and pharmacokinetics

29 September 2017

1 reference

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Human alpha-1-glycoprotein and its interactions with drugs

29 September 2017

1 reference

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Binding of prazosin and propranolol at variable alpha 1-acid glycoprotein and albumin concentrations

29 September 2017

1 reference

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A simple method for predicting serum protein binding of compounds from IC(50) shift analysis for in vitro assays.

29 September 2017

1 reference

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Efficacy of venlafaxine for the long term treatment of chronic pain with associated major depressive disorder

2 June 2018

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Relations between high-affinity binding sites of markers for binding regions on human serum albumin

2 June 2018

1 reference

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The stereoselectivity of the 'single drug binding site' of human alpha 1-acid glycoprotein (orosomucoid).

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447978

High-throughput determination of the free fraction of drugs strongly bound to plasma proteins.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447978

The peripheral benzodiazepine receptor ligand PK11195 binds with high affinity to the acute phase reactant alpha1-acid glycoprotein: implications for the use of the ligand as a CNS inflammatory marker

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3447978

Differences in the serum protein binding of prazosin in man and rat.

27 November 2018

1 reference

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Respective role of mifepristone (RU486) binding to blood and tissue proteins in its quantitative distribution in the body

27 November 2018

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12 December 2020

Further characterization of specific drug binding sites on human serum albumin

1 reference

12 December 2020

The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery

1 reference

12 December 2020

Predicting plasma protein binding of drugs: a new approach

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12 December 2020

The characterization of two specific drug binding sites on human serum albumin

1 reference

12 December 2020

Binding of prazosin to alpha 1-acid glycoprotein and albumin: effect of protein purity and concentrations

1 reference

12 December 2020