(Q28485876)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

title

NMR structure of integrin α4 cytosolic tail and its interactions with paxillin (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Suet-Mien Tan

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

author name string

Geok-Lin Chua

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

Surajit Bhattacharjya

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

language of work or name

English

0 references

publication date

31 January 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

page(s)

e55184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

23 February 2020

copyright license

start time

31 January 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Structural basis for paxillin binding and focal adhesion targeting of β-parvin

1 reference

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Structures and Interaction Analyses of Integrin M 2 Cytoplasmic Tails

19 March 2017

1 reference

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NMR solution conformations and interactions of integrin alphaLbeta2 cytoplasmic tails

19 March 2017

1 reference

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The Structure of -Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly

19 March 2017

1 reference

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Molecular recognition of paxillin LD motifs by the focal adhesion targeting domain

19 March 2017

1 reference

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Integrins: bidirectional, allosteric signaling machines

19 March 2017

1 reference

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A fragment of paxillin binds the alpha 4 integrin cytoplasmic domain (tail) and selectively inhibits alpha 4-mediated cell migration

19 March 2017

1 reference

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Structural insight into the mechanisms of targeting and signaling of focal adhesion kinase

19 March 2017

1 reference

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The focal adhesion targeting (FAT) region of focal adhesion kinase is a four-helix bundle that binds paxillin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

The cytoplasmic domain of the integrin alpha9 subunit requires the adaptor protein paxillin to inhibit cell spreading but promotes cell migration in a paxillin-independent manner

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Phosphorylation of the integrin alpha 4 cytoplasmic domain regulates paxillin binding

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Paxillin and focal adhesion signalling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

A structural basis for integrin activation by the cytoplasmic tail of the alpha IIb-subunit

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Binding of paxillin to alpha4 integrins modifies integrin-dependent biological responses

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Intact LIM 3 and LIM 4 domains of paxillin are required for the association to a novel polyproline region (Pro 2) of protein-tyrosine phosphatase-PEST

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Direct association of protein-tyrosine phosphatase PTP-PEST with paxillin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Torsion angle dynamics for NMR structure calculation with the new program DYANA

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Force Sensing by Mechanical Extension of the Src Family Kinase Substrate p130Cas

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Mechanical control of integrin-mediated adhesion and signaling

6 April 2017

1 reference

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The leucocyte β2 (CD18) integrins: the structure, functional regulation and signalling properties

29 September 2017

1 reference

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Integrins in cell migration

29 September 2017

1 reference

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A small molecule that inhibits the interaction of paxillin and alpha 4 integrin inhibits accumulation of mononuclear leukocytes at a site of inflammation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

The mechanical integrin cycle.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Integrins and cell-fate determination

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Integrins and the actin cytoskeleton

29 September 2017

1 reference

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The role of the alpha4 integrin-paxillin interaction in regulating leukocyte trafficking

29 September 2017

1 reference

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Blocking the alpha 4 integrin-paxillin interaction selectively impairs mononuclear leukocyte recruitment to an inflammatory site

29 September 2017

1 reference

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Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale.

29 September 2017

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Novel approaches to treating inflammatory bowel disease: targeting alpha-4 integrin

29 September 2017

1 reference

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Spatial restriction of alpha4 integrin phosphorylation regulates lamellipodial stability and alpha4beta1-dependent cell migration

29 September 2017

1 reference

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Mapping protein-protein interactions in solution by NMR spectroscopy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Analysis of the alpha4beta1 integrin-osteopontin interaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Alpha 4 beta 1 integrin/VCAM-1 interaction activates alpha L beta 2 integrin-mediated adhesion to ICAM-1 in human T cells

29 September 2017

1 reference

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Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue

29 September 2017

1 reference

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Specialized functional properties of the integrin alpha 4 cytoplasmic domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Structure and binding interface of the cytosolic tails of αXβ2 integrin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

An alpha4 integrin-paxillin-Arf-GAP complex restricts Rac activation to the leading edge of migrating cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Paxillin binding to a conserved sequence motif in the alpha 4 integrin cytoplasmic domain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Alpha 4 beta 7 integrin mediates lymphocyte binding to the mucosal vascular addressin MAdCAM-1.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

alpha 4 integrins mediate lymphocyte attachment and rolling under physiologic flow

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Binding of Paxillin to the alpha 9 Integrin Cytoplasmic Domain Inhibits Cell Spreading

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055184

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0055184

The CS5 peptide is a second site in the IIICS region of fibronectin recognized by the integrin alpha 4 beta 1. Inhibition of alpha 4 beta 1 function by RGD peptide homologues

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3561355

Differential requirements for alpha4 integrins during fetal and adult hematopoiesis

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23383101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

VLA-4 (alpha(4)beta(1)) engagement defines a novel activation pathway for beta(2) integrin-dependent leukocyte adhesion involving the urokinase receptor

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23383101

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0055184

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json

23 February 2020

PubMed publication ID

23383101

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23383101%20AND%20SRC:MED&resulttype=core&format=json