(Q28486954)

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis. Mutational and structural characterization of the active site and the fold (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

Mycobacterium tuberculosis

7 January 2020

main subject

0 references

(2R)-2-methyltetradecanoyl-CoA(4-)

1 reference

(2S)-2-methyltetradecanoyl-CoA(4-)

ChEBI release 2020-05-28

ChEBI ID

86520

1 reference

ChEBI release 2020-05-28

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

J Kalervo Hiltunen

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

6

Rik K Wierenga

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

author name string

Prasenjit Bhaumik

2

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Werner Schmitz

3

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Ernst Conzelmann

5

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

Tiina J Kotti

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

language of work or name

English

0 references

publication date

4 January 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

7 January 2020

published in

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

volume

280

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

issue

13

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

page(s)

12611-12620

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

Purification and properties of an alpha-methylacyl-CoA racemase from rat liver

7 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

In mouse alpha -methylacyl-CoA racemase, the same gene product is simultaneously located in mitochondria and peroxisomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Substrate stereospecificity in oxidation of (25S)-3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-cholestanoyl-CoA by peroxisomal trihydroxy-5 beta-cholestanoyl-CoA oxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Stereochemistry of peroxisomal and mitochondrial beta-oxidation of alpha-methylacyl-CoAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

The enzymes, regulation, and genetics of bile acid synthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

beta-oxidation - strategies for the metabolism of a wide variety of acyl-CoA esters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Fibroblast studies documenting a case of peroxisomal 2-methylacyl-CoA racemase deficiency: possible link between racemase deficiency and malabsorption and vitamin K deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

A mouse model for alpha-methylacyl-CoA racemase deficiency: adjustment of bile acid synthesis and intolerance to dietary methyl-branched lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

P504S: a new molecular marker for the detection of prostate carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Elevated alpha-methylacyl-CoA racemase enzymatic activity in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Molecular subclassification of kidney tumors and the discovery of new diagnostic markers

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Evidence for a multigene family involved in bile acid 7-dehydroxylation in Eubacterium sp. strain VPI 12708

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

A new family of CoA-transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Formyl-CoA transferase encloses the CoA binding site at the interface of an interlocked dimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Kinetic and mechanistic characterization of the formyl-CoA transferase from Oxalobacter formigenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

The crystal structure of the Escherichia coli YfdW gene product reveals a new fold of two interlaced rings identifying a wide family of CoA transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Structure of Escherichia coli YfdW, a type III CoA transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Crystal structure of aspartate racemase from Pyrococcus horikoshii OT3 and its implications for molecular mechanism of PLP-independent racemization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Structure and catalytic mechanism of the cytosolic D-ribulose-5-phosphate 3-epimerase from rice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Role of alpha-methylacyl coenzyme A racemase in the degradation of methyl-branched alkanes by Mycobacterium sp. strain P101

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Crystallization and preliminary X-ray diffraction studies of an alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Purification and Characterization of an alpha-Methylacyl-CoA Racemase from Human Liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

The CLUSTAL_X windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Solvent content of protein crystals

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

The CCP4 suite: programs for protein crystallography

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Automated MAD and MIR structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Maximum-likelihood density modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Refinement of macromolecular structures by the maximum-likelihood method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Determinants of function and substrate specificity in human UDP-galactose 4'-epimerase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Multiple substrate binding states and chiral recognition in cofactor-independent glutamate racemase: a molecular dynamics study

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

The crotonase superfamily: divergently related enzymes that catalyze different reactions involving acyl coenzyme a thioesters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

Evolution of enzymatic activities in the enolase superfamily: structure of a substrate-liganded complex of the L-Ala-D/L-Glu epimerase from Bacillus subtilis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M409704200

21 January 2018

Identifiers

DOI

10.1074/JBC.M409704200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15632186%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

2 references

24 January 2017