(Q28504700)

24 January 2017

title

A critical role for Apc in hematopoietic stem and progenitor cell survival (English)

1 reference

Adenomatous polyposis coli protein

24 January 2017

main subject

1 reference

GOA release 2020-03-11

5

Michelle M. Le Beau

1 reference

24 January 2017

Zhijian Qian

1

1 reference

24 January 2017

Lina Chen

series ordinal

2

1 reference

24 January 2017

Anthony A. Fernald

series ordinal

3

1 reference

24 January 2017

Bart O. Williams

series ordinal

4

1 reference

24 January 2017

language of work or name

English

0 references

publication date

1 September 2008

1 reference

Journal of Experimental Medicine

24 January 2017

published in

1 reference

24 January 2017

volume

205

1 reference

24 January 2017

issue

9

1 reference

24 January 2017

page(s)

2163–2175

1 reference

TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth

24 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Slug antagonizes p53-mediated apoptosis of hematopoietic progenitors by repressing puma

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Loss of adenomatous polyposis coli gene function disrupts thymic development

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Essential role of beta-catenin in postnatal bone acquisition

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Cystic renal neoplasia following conditional inactivation of apc in mouse renal tubular epithelium

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

A role for Wnt signalling in self-renewal of haematopoietic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Apoptosis in neural crest cells by functional loss of APC tumor suppressor gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Therapy-related myeloid leukemia

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

The tumour suppressor gene product APC blocks cell cycle progression from G0/G1 to S phase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Wnt proteins are lipid-modified and can act as stem cell growth factors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

A clonogenic common myeloid progenitor that gives rise to all myeloid lineages

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Inducible gene targeting in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Requirements for survivin in terminal differentiation of erythroid cells and maintenance of hematopoietic stem and progenitor cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Zfx controls the self-renewal of embryonic and hematopoietic stem cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Wnt signalling and the actin cytoskeleton

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Hematopoietic stem cell self-renewal

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Non-traditional roles for the Adenomatous Polyposis Coli (APC) tumor suppressor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Transcription factor Gfi1 regulates self-renewal and engraftment of hematopoietic stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Cell cycle inhibitors in normal and tumor stem cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Tel/Etv6 is an essential and selective regulator of adult hematopoietic stem cell survival

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Adenomatous polyposis coli proteins and cell adhesion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Beta-catenin is dispensable for hematopoiesis and lymphopoiesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

APC, signal transduction and genetic instability in colorectal cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

APC expression in normal human tissues

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Quiescence, cycling, and turnover in the primitive hematopoietic stem cell compartment.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

The APC gene product in normal and tumor cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Identification of clonogenic common lymphoid progenitors in mouse bone marrow

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Mouse strain-dependent changes in frequency and proliferation of hematopoietic stem cells during aging: correlation between lifespan and cycling activity.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

Gfi-1 restricts proliferation and preserves functional integrity of haematopoietic stem cells

2 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

HOXB4-induced expansion of adult hematopoietic stem cells ex vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

In vitro expansion of hematopoietic stem cells by recombinant TAT-HOXB4 protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Rapid colorectal adenoma formation initiated by conditional targeting of the Apc gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Stem cell repopulation efficiency but not pool size is governed by p27(kip1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Activation of the canonical Wnt pathway leads to loss of hematopoietic stem cell repopulation and multilineage differentiation block.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Orientation of asymmetric stem cell division by the APC tumor suppressor and centrosome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Hematopoietic stem cell and multilineage defects generated by constitutive β-catenin activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Apc deficiency predisposes to renal carcinoma in the mouse

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526209

PTEN maintains haematopoietic stem cells and acts in lineage choice and leukaemia prevention

27 November 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080578

Hematopoietic stem cell quiescence maintained by p21cip1/waf1

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/18725524

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20080578

1 reference

1 reference

1 reference

1 reference