(Q28509199)

24 January 2017

title

Distinct pathways involving the FK506-binding proteins 12 and 12.6 underlie IL-2-versus IL-15-mediated proliferation of T cells (English)

1 reference

24 January 2017

main subject

FK506 binding protein 1b

1 reference

GOA release 2020-03-11

FK506 binding protein 1a

1 reference

GOA release 2020-03-11

3

Laura S. Haneline

1 reference

24 January 2017

5

Thomas A. Waldmann

1 reference

24 January 2017

Sigrid Dubois

1

1 reference

24 January 2017

Weinian Shou

2

1 reference

24 January 2017

Sidney Fleischer

4

1 reference

24 January 2017

Jürgen R. Müller

6

1 reference

24 January 2017

Thomas A. Waldmann

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14605212

30 March 2024

language of work or name

English

0 references

publication date

25 November 2003

1 reference

24 January 2017

6 November 2003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14605212

full work available at URL

30 March 2024

https://europepmc.org/articles/pmc283564?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14605212

https://europepmc.org/articles/PMC283564

30 March 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14605212

https://europepmc.org/articles/PMC283564?pdf=render

30 March 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14605212

https://doi.org/10.1073/pnas.2335979100

30 March 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14605212

https://pnas.org/doi/pdf/10.1073/pnas.2335979100

30 March 2024

1 reference

DOI

10.1073/PNAS.2335979100

https://api.crossref.org/works/10.1073/PNAS.2335979100

Proceedings of the National Academy of Sciences of the United States of America

30 March 2024

published in

1 reference

24 January 2017

volume

100

1 reference

24 January 2017

issue

24

1 reference

24 January 2017

page(s)

14169–14174

1 reference

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

24 January 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Mechanisms of resistance to rapamycins

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

TOR, a central controller of cell growth

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Reversible defects in natural killer and memory CD8 T cell lineages in interleukin 15-deficient mice

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Death deflected: IL-15 inhibits TNF-alpha-mediated apoptosis in fibroblasts by TRAF2 recruitment to the IL-15Ralpha chain

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Cardiac defects and altered ryanodine receptor function in mice lacking FKBP12

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Distinct tyrosine residues within the interleukin-2 receptor beta chain drive signal transduction specificity, redundancy, and diversity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

The adapter protein Shc interacts with the interleukin-2 (IL-2) receptor upon IL-2 stimulation

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Interleukin-2 receptor α chain regulates the size and content of the peripheral lymphoid compartment

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Analysis of interleukin-2-dependent signal transduction through the Shc/Grb2 adapter pathway. Interleukin-2-dependent mitogenesis does not require Shc phosphorylation or receptor association

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Regulation of translation initiation by FRAP/mTOR

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

The IL-15R alpha chain signals through association with Syk in human B cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

mTOR inhibitors: an overview

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Signaling domains of the interleukin 2 receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Contrasting roles of IL-2 and IL-15 in the life and death of lymphocytes: implications for immunotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

FKBP12, the 12-kDa FK506-binding protein, is a physiologic regulator of the cell cycle

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

IL-2-induced activation-induced cell death is inhibited in IL-15 transgenic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Functional dissection of the cytoplasmic subregions of the IL-2 receptor betac chain in primary lymphocyte populations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Preassembly of interleukin 2 (IL-2) receptor subunits on resting Kit 225 K6 T cells and their modulation by IL-2, IL-7, and IL-15: a fluorescence resonance energy transfer study

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Quiescence-inducing and antiapoptotic activities of IL-15 enhance secondary CD4+ T cell responsiveness to antigen.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=283564

Interleukin-15 protects from lethal apoptosis in vivo.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

FKBP12 is the only FK506 binding protein mediating T-cell inhibition by the immunosuppressant FK506.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

Oestrogen protects FKBP12.6 null mice from cardiac hypertrophy

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

Immune responses in interleukin-2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

IL-15 receptor maintains lymphoid homeostasis by supporting lymphocyte homing and proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

Phosphatidylinositol 3-kinase couples the interleukin-2 receptor to the cell cycle regulator E2F

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

Immunophilins in the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2335979100

Subunit structure of the high and low affinity human interleukin-15 receptors

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/14605212

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Wild type p53 stimulates expression from the human multidrug resistance promoter in a p53-negative cell line

12

1 reference

DOI

10.1073/PNAS.2335979100

https://api.crossref.org/works/10.1073/PNAS.2335979100

30 March 2024

Identifiers

DOI

10.1073/PNAS.2335979100

0 references

0 references

0 references

1 reference