(Q28509265)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

title

TDP1 facilitates chromosomal single-strand break repair in neurons and is neuroprotective in vivo (English)

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

Tyrosyl-DNA phosphodiesterase 1

8 January 2020

main subject

1 reference

GOA release 2020-03-11

author

Sachin Katyal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

author name string

Yang Li

4

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Limei Ju

5

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Sherif F el-Khamisy

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Helen R Russell

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Keith W Caldecott

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Peter J McKinnon

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

language of work or name

English

0 references

publication date

4 October 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

volume

26

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

page(s)

4720-4731

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

issue

22

2 references

24 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

8 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2080805/fullTextXML

inferred from PubMed Central ID database lookup

cites work

TDP1 facilitates repair of ionizing radiation-induced DNA single-strand breaks

1 reference

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Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

19 March 2017

1 reference

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Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

19 March 2017

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Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

19 March 2017

1 reference

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Repair of and checkpoint response to topoisomerase I-mediated DNA damage

19 March 2017

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19 March 2017

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Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

19 March 2017

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8-Oxoguanine rearranges the active site of human topoisomerase I

19 March 2017

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19 March 2017

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Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

19 March 2017

1 reference

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Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

19 March 2017

1 reference

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

19 March 2017

1 reference

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DNA single-strand break repair and spinocerebellar ataxia with axonal neuropathy-1.

19 March 2017

1 reference

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Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes

29 September 2017

1 reference

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Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages

29 September 2017

1 reference

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29 September 2017

1 reference

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SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

29 September 2017

1 reference

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Engineered resistance to camptothecin and antifolates by retroviral coexpression of tyrosyl DNA phosphodiesterase-I and thymidylate synthase

29 September 2017

1 reference

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The mechanism and regulation of chromosomal V(D)J recombination

29 September 2017

1 reference

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29 September 2017

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29 September 2017

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Linking DNA damage and neurodegeneration

29 September 2017

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Gut instincts: thoughts on intestinal epithelial stem cells

29 September 2017

1 reference

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Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

29 September 2017

1 reference

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Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

29 September 2017

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A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

29 September 2017

1 reference

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Neuronal regulation of astroglial morphology and proliferation in vitro

29 September 2017

1 reference

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Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene

29 September 2017

1 reference

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Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

29 September 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

29 September 2017

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601869

7 January 2021

inferred from DOI database lookup

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

glaikit is essential for the formation of epithelial polarity and neuronal development.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Differential requirement of DNA replication for the cytotoxicity of DNA topoisomerase I and II inhibitors in Chinese hamster DC3F cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Genotoxicity of two anticancer drugs, gemcitabine and topotecan, in mouse bone marrow in vivo

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FSJ.EMBOJ.7601869

Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2080805

Camptothecin induces protein-linked DNA breaks via mammalian DNA topoisomerase I

27 November 2018

1 reference

12 December 2020

Cell killing and DNA damage in Chinese hamster V79 cells treated with hydrogen peroxide

1 reference

12 December 2020

Arrest of replication forks by drug-stabilized topoisomerase I-DNA cleavable complexes as a mechanism of cell killing by camptothecin

1 reference

12 December 2020

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

1 reference

12 December 2020

Activation of ataxia telangiectasia mutated by DNA strand break-inducing agents correlates closely with the number of DNA double strand breaks

1 reference

12 December 2020

Mapping of eukaryotic DNA topoisomerase I catalyzed cleavage without concomitant religation in the vicinity of DNA structural anomalies

1 reference

12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601869

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17914460%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

2 references

24 January 2017