(Q24315895)

single strand break repair

GOA release 2020-03-11

1 reference

Simple procedure for isolation of DNA, RNA and protein fractions from cultured animal cells

GOA release 2020-03-11

author name string

Sherif F El-Khamisy

series ordinal

1

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Edgar Hartsuiker

series ordinal

2

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Keith W Caldecott

series ordinal

3

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language of work or name

English

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publication date

1 October 2007

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published in

DNA Repair

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volume

6

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issue

10

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page(s)

1485-95

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Camptothecin inhibits both the cleavage and religation reactions of eukaryotic DNA topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Hereditary ataxia SCAN1 cells are defective for the repair of transcription-dependent topoisomerase I cleavage complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Meiosis-specific DNA double-strand breaks are catalyzed by Spo11, a member of a widely conserved protein family

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Mechanism of action of eukaryotic DNA topoisomerase I and drugs targeted to the enzyme

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Mapping of eukaryotic DNA topoisomerase I catalyzed cleavage without concomitant religation in the vicinity of DNA structural anomalies

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Crystal structure of a transition state mimic for Tdp1 assembled from vanadate, DNA, and a topoisomerase I-derived peptide

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

DNA ligase IV mutations identified in patients exhibiting developmental delay and immunodeficiency

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

ATM deficiency and oxidative stress: a new dimension of defective response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Association of XRCC1 and tyrosyl DNA phosphodiesterase (Tdp1) for the repair of topoisomerase I-mediated DNA lesions

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Camptothecin-stabilized topoisomerase I-DNA adducts cause premature termination of transcription

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Instability and decay of the primary structure of DNA

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Gene regulation and DNA damage in the ageing human brain

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Defective DNA single-strand break repair in spinocerebellar ataxia with axonal neuropathy-1

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Mutation of TDP1, encoding a topoisomerase I-dependent DNA damage repair enzyme, in spinocerebellar ataxia with axonal neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

SCAN1 mutant Tdp1 accumulates the enzyme--DNA intermediate and causes camptothecin hypersensitivity

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Tyrosyl-DNA phosphodiesterase (Tdp1) participates in the repair of Top2-mediated DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Repair of topoisomerase I covalent complexes in the absence of the tyrosyl-DNA phosphodiesterase Tdp1.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Position-specific trapping of topoisomerase I-DNA cleavage complexes by intercalated benzo[a]- pyrene diol epoxide adducts at the 6-amino group of adenine

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

8-Oxoguanine rearranges the active site of human topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

The tyrosyl-DNA phosphodiesterase Tdp1 is a member of the phospholipase D superfamily

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

An activity from mammalian cells that untwists superhelical DNA--a possible swivel for DNA replication (polyoma-ethidium bromide-mouse-embryo cells-dye binding assay).

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

A eukaryotic enzyme that can disjoin dead-end covalent complexes between DNA and type I topoisomerases

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Effects of uracil incorporation, DNA mismatches, and abasic sites on cleavage and religation activities of mammalian topoisomerase I.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Ubiquitin-dependent destruction of topoisomerase I is stimulated by the antitumor drug camptothecin

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Trapping of mammalian topoisomerase I and recombinations induced by damaged DNA containing nicks or gaps. Importance of DNA end phosphorylation and camptothecin effects

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Induction of reversible complexes between eukaryotic DNA topoisomerase I and DNA-containing oxidative base damages. 7, 8-dihydro-8-oxoguanine and 5-hydroxycytosine

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Conversion of phosphoglycolate to phosphate termini on 3' overhangs of DNA double strand breaks by the human tyrosyl-DNA phosphodiesterase hTdp1

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Structural impact of the leukemia drug 1-beta-D-arabinofuranosylcytosine (Ara-C) on the covalent human topoisomerase I-DNA complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Hydrogen peroxide induces topoisomerase I-mediated DNA damage and cell death.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Substrate specificity of tyrosyl-DNA phosphodiesterase I (Tdp1)

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Human Tdp1 cleaves a broad spectrum of substrates, including phosphoamide linkages

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Radiation-induced DNA damage and its repair.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Interaction of topoisomerase 1 with the transcribed region of the Drosophila HSP 70 heat shock gene

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Camptothecin cytotoxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Characterization of the XRCC1-DNA ligase III complex in vitro and its absence from mutant hamster cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

XRCC1 polypeptide interacts with DNA polymerase beta and possibly poly (ADP-ribose) polymerase, and DNA ligase III is a novel molecular 'nick-sensor' in vitro

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Processing of topoisomerase I cleavable complexes into DNA damage by transcription.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Processing of nucleopeptides mimicking the topoisomerase I-DNA covalent complex by tyrosyl-DNA phosphodiesterase

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

X-ray induced DNA double strand break production and repair in mammalian cells as measured by neutral filter elution

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Impact of DNA ligase IV on the fidelity of end joining in human cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

APE1 is the major 3'-phosphoglycolate activity in human cell extracts

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Deficiency in 3'-phosphoglycolate processing in human cells with a hereditary mutation in tyrosyl-DNA phosphodiesterase (TDP1)

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Formation of 7,8-dihydro-8-oxoguanine in the 1,2-dioxetane-induced oxidation of calf thymus DNA: evidence for photosensitized DNA damage by thermally generated triplet ketones in the dark.

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

A model for the mechanism of human topoisomerase I

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Yeast gene for a Tyr-DNA phosphodiesterase that repairs topoisomerase I complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Conversion of topoisomerase I cleavage complexes on the leading strand of ribosomal DNA into 5'-phosphorylated DNA double-strand breaks by replication runoff

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Camptothecin, a specific inhibitor of type I DNA topoisomerase, induces DNA breakage at replication forks

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Cullin 3 promotes proteasomal degradation of the topoisomerase I-DNA covalent complex

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Defective DNA Strand Break Repair after DNA Damage in Prostate Cancer Cells

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

After double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are available

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021

Heterogeneity in radiation-induced DNA damage and repair in tumor and normal cells measured using the "comet" assay

1 reference

https://api.crossref.org/works/10.1016%2FJ.DNAREP.2007.04.015

7 January 2021