(Q28541949)

English

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER

scientific article (publication date: April 2014)

In more languages

Statements

scholarly article

0 references

The pathogenic mechanism of the Mycobacterium ulcerans virulence factor, mycolactone, depends on blockade of protein translocation into the ER (English)

0 references

0 references

Mycobacterium ulcerans

0 references

Michael McKenna

object named as

Michael McKenna

3

0 references

Rachel E Simmonds

object named as

Rachel E Simmonds

7

0 references

Belinda S. Hall

object named as

Belinda S Hall

1

0 references

object named as

Stephen High

5

0 references

4

object named as

Joy Ogbechi

0 references

author name string

Kirsti Hill

2

0 references

Anne E Willis

6

0 references

language of work or name

0 references

publication date

April 2014

0 references

0 references

10

0 references

4

0 references

e1004061

0 references

copyright license

Creative Commons Attribution 4.0 International

3 April 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3974873/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Bactericidal activity does not predict sterilizing activity: the case of rifapentine in the murine model of Mycobacterium ulcerans disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Cell elasticity determines macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

The ERAD inhibitor Eeyarestatin I is a bifunctional compound with a membrane-binding domain and a p97/VCP inhibitory group

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Mycolactone diffuses from Mycobacterium ulcerans-infected tissues and targets mononuclear cells in peripheral blood and lymphoid organs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

P2X7 receptor differentially couples to distinct release pathways for IL-1beta in mouse macrophage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Development of highly organized lymphoid structures in Buruli ulcer lesions after treatment with rifampicin and streptomycin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

kappa-casein-deficient mice fail to lactate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

X-ray structure of a protein-conducting channel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

A Mycobacterium ulcerans toxin, mycolactone, causes apoptosis in guinea pig ulcers and tissue culture cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Mycolactone: a polyketide toxin from Mycobacterium ulcerans required for virulence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

19 March 2017

Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

7 April 2017

Pleiotropic molecular effects of the Mycobacterium ulcerans virulence factor mycolactone underlying the cell death and immunosuppression seen in Buruli ulcer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Mycolactone activation of Wiskott-Aldrich syndrome proteins underpins Buruli ulcer formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Microbiological, histological, immunological, and toxin response to antibiotic treatment in the mouse model of Mycobacterium ulcerans disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Corticosteroid-induced immunosuppression ultimately does not compromise the efficacy of antibiotherapy in murine Mycobacterium ulcerans infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Local and regional re-establishment of cellular immunity during curative antibiotherapy of murine Mycobacterium ulcerans infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Paradoxical responses after start of antimicrobial treatment in Mycobacterium ulcerans infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Tail-anchored membrane protein insertion into the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Effect of rifampin on production of inflammatory mediators in HepG2 liver epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Mycolactone impairs T cell homing by suppressing microRNA control of L-selectin expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Inflammasome activation and IL-1β and IL-18 processing during infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Chemical and pharmacological chaperones: application for recombinant protein production and protein folding diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Mycobacterium ulcerans triggers T-cell immunity followed by local and regional but not systemic immunosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

WASP: a key immunological multitasker

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Eeyarestatin I inhibits Sec61-mediated protein translocation at the endoplasmic reticulum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Biogenesis of tail-anchored proteins: the beginning for the end?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Analysis of mRNA partitioning between the cytosol and endoplasmic reticulum compartments of mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Post-transcriptional control of cytokine production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Signalling, inflammation and arthritis: NF-kappaB and its relevance to arthritis and inflammation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Selective suppression of dendritic cell functions by Mycobacterium ulcerans toxin mycolactone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Mycolactone-mediated inhibition of tumor necrosis factor production by macrophages infected with Mycobacterium ulcerans has implications for the control of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Infection with Mycobacterium ulcerans induces persistent inflammatory responses in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Mycobacterium ulcerans toxic macrolide, mycolactone modulates the host immune response and cellular location of M. ulcerans in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Modulation of the host immune response by a transient intracellular stage of Mycobacterium ulcerans: the contribution of endogenous mycolactone toxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Partitioning and translation of mRNAs encoding soluble proteins on membrane-bound ribosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Regulation of protein transport from the Golgi complex to the endoplasmic reticulum by CDC42 and N-WASP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Immune response to infection with Mycobacterium ulcerans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

The inhibitory action of Mycobacterium ulcerans soluble factor on monocyte/T cell cytokine production and NF-kappa B function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Cap-independent polysomal association of natural mRNAs encoding c-myc, BiP, and eIF4G conferred by internal ribosome entry sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Mechanism of Puromycin Action: Fate of Ribosomes after Release of Nascent Protein Chains from Polysomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

29 September 2017

Inhibition of protein translocation at the endoplasmic reticulum promotes activation of the unfolded protein response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

3 June 2018

Mycolactone suppresses T cell responsiveness by altering both early signaling and posttranslational events

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

3 June 2018

The 19-amino acid cassette of cyclooxygenase-2 mediates entry of the protein into the endoplasmic reticulum-associated degradation system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

3 June 2018

The translocation, folding, assembly and redox-dependent degradation of secretory and membrane proteins in semi-permeabilized mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3974873

3 June 2018

Buruli ulcer: reductive evolution enhances pathogenicity of Mycobacterium ulcerans

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Mycolactone inhibits monocyte cytokine production by a posttranscriptional mechanism.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Immunosuppressive signature of cutaneous Mycobacterium ulcerans infection in the peripheral blood of patients with buruli ulcer disease

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Efficient sorting of TNF-alpha to rodent mast cell granules is dependent on N-linked glycosylation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Uptake and cellular actions of mycolactone, a virulence determinant for Mycobacterium ulcerans

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Potential of rifamides to inhibit TNF-induced NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Preparation of microsomal membranes for cotranslational protein translocation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Acquired T‐helper 1 Lymphocyte Anergy Following Infection withMycobacterium ulcerans

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PPAT.1004061

21 January 2018

Total synthesis of the mycolactones

1 reference

https://pubmed.ncbi.nlm.nih.gov/24699819

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PPAT.1004061

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28541949&oldid=1862166842"