(Q28543168)

English

3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems

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scholarly article

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3-Dimensional culture systems for anti-cancer compound profiling and high-throughput screening reveal increases in EGFR inhibitor-mediated cytotoxicity compared to monolayer culture systems (English)

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high-throughput screening

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author name string

Amy L Howes

1

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Robyn D Richardson

2

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Darren Finlay

3

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Kristiina Vuori

4

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language of work or name

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publication date

2014

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9

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9

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e108283

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copyright license

Creative Commons Attribution 4.0 International

23 September 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

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1 reference

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1 reference

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Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling

1 reference

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19 March 2017

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1 reference

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19 March 2017

The third dimension bridges the gap between cell culture and live tissue

1 reference

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7 April 2017

Stromal fibroblasts in cancer initiation and progression

1 reference

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7 April 2017

Live multicellular tumor spheroid models for high-content imaging and screening in cancer drug discovery

1 reference

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29 September 2017

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

1 reference

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29 September 2017

Miniaturized pre-clinical cancer models as research and diagnostic tools

1 reference

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29 September 2017

Evaluation of nanoparticle uptake in co-culture cancer models

1 reference

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29 September 2017

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1 reference

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29 September 2017

Spheroid culture as a tool for creating 3D complex tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172726

29 September 2017

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172726

29 September 2017

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172726

29 September 2017

The microenvironment determines the breast cancer cells' phenotype: organization of MCF7 cells in 3D cultures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172726

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1 reference

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29 September 2017

Multicellular tumor spheroids: an underestimated tool is catching up again.

1 reference

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29 September 2017

Small-molecule inhibitors of the human epidermal receptor family.

1 reference

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Inhibition of mammalian target of rapamycin is required for optimal antitumor effect of HER2 inhibitors against HER2-overexpressing cancer cells

1 reference

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29 September 2017

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

1 reference

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29 September 2017

Modeling tissue morphogenesis and cancer in 3D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4172726

29 September 2017

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

1 reference

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29 September 2017

Three-dimensional tissue culture models in cancer biology

1 reference

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29 September 2017

Potential of fibroblasts to regulate the formation of three-dimensional vessel-like structures from endothelial cells in vitro.

1 reference

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3 June 2018

Comparison of 3D and 2D tumor models reveals enhanced HER2 activation in 3D associated with an increased response to trastuzumab.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0108283

21 January 2018

Novel in vitro co-culture methodology to investigate heterotypic cell-cell interactions

1 reference

https://pubmed.ncbi.nlm.nih.gov/25247711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Generation of multicellular tumor spheroids by the hanging-drop method

1 reference

https://pubmed.ncbi.nlm.nih.gov/25247711

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0108283

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2014PLoSO...9j8283H

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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