(Q28547077)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

title

Calcineurin Undergoes a Conformational Switch Evoked via Peptidyl-Prolyl Isomerization (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

Nuclear factor of activated T cells 2

1 reference

Protein phosphatase 3 catalytic subunit alpha

1 reference

phosphatase binding

1 reference

author

Eva Serrano-Candelas

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Merce Perez-Riba

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

author name string

Alicia Guasch

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Álvaro Aranguren-Ibáñez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Rosa Pérez-Luque

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

David Aparicio

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Sergio Martínez-Høyer

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

M Carmen Mulero

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

Ignacio Fita

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

language of work or name

English

0 references

publication date

6 August 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

volume

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

issue

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

page(s)

e0134569

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

21 February 2020

copyright license

start time

6 August 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

mTOR kinase structure, mechanism and regulation

1 reference

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The Molecular Mechanism of Substrate Engagement and Immunosuppressant Inhibition of Calcineurin

19 March 2017

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Balanced interactions of calcineurin with AKAP79 regulate Ca2+–calcineurin–NFAT signaling

19 March 2017

1 reference

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REFMAC5 for the refinement of macromolecular crystal structures

19 March 2017

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iMOSFLM: a new graphical interface for diffraction-image processing with MOSFLM

19 March 2017

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Serine/threonine phosphatases: mechanism through structure

19 March 2017

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Jalview Version 2--a multiple sequence alignment editor and analysis workbench

19 March 2017

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Prolyl cis-trans isomerization as a molecular timer

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Structure of the Calcineurin-NFAT Complex: Defining a T Cell Activation Switch Using Solution NMR and Crystal Coordinates

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Structure of calcineurin in complex with PVIVIT peptide: portrait of a low-affinity signalling interaction

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Coot: model-building tools for molecular graphics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Crystal structure of human calcineurin complexed with cyclosporin A and human cyclophilin

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Structural basis for the recognition of regulatory subunits by the catalytic subunit of protein phosphatase 1

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Biological effects of cyclosporin A: A new antilymphocytic agent

19 March 2017

1 reference

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Multiple alignment of DNA sequences with MAFFT

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Structural basis for protein phosphatase 1 regulation and specificity

7 April 2017

1 reference

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Cracking the phosphatase code: docking interactions determine substrate specificity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4527731

Chronic calcineurin inhibitor nephrotoxicity: reflections on an evolving paradigm

29 September 2017

1 reference

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From promiscuity to precision: protein phosphatases get a makeover

29 September 2017

1 reference

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Inhibiting the calcineurin-NFAT (nuclear factor of activated T cells) signaling pathway with a regulator of calcineurin-derived peptide without affecting general calcineurin phosphatase activity

29 September 2017

1 reference

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Model preparation in MOLREP and examples of model improvement using X-ray data

29 September 2017

1 reference

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Calcineurin regulation in fungi and beyond

29 September 2017

1 reference

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Calcineurin: from structure to function

29 September 2017

1 reference

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Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

29 September 2017

1 reference

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Immunophilins interact with calcineurin in the absence of exogenous immunosuppressive ligands

29 September 2017

1 reference

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Mutagenesis of the L7 loop connecting beta strands 12 and 13 of calcineurin: evidence for a structural role in activity changes.

29 September 2017

1 reference

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Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.

3 June 2018

1 reference

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Crystal structure and mutagenesis of a protein phosphatase-1:calcineurin hybrid elucidate the role of the beta12-beta13 loop in inhibitor binding

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0134569

Protein kinase CK2-dependent phosphorylation of the human Regulators of Calcineurin reveals a novel mechanism regulating the calcineurin-NFATc signaling pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0134569

Regulation of calcineurin phosphatase activity by its autoinhibitory domain

21 January 2018

1 reference

12 December 2020

Cis peptide bonds in proteins: residues involved, their conformations, interactions and locations

1 reference

12 December 2020

Blockade of NFAT activation by the second calcineurin binding site

1 reference

12 December 2020

The beta12-beta13 loop is a key regulatory element for the activity and properties of the catalytic domain of protein phosphatase 1 and 2B

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0134569

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json

21 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26248042%20AND%20SRC:MED&resulttype=core&format=json