(Q28550521)

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An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway

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An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway (English)

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Eylan Yutuc

7

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Thorsten Forster

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Thorsten Forster

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object named as

Ana Angulo

21

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object named as

Yuqin Wang

20

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object named as

Peter Ghazal

22

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Anton J. Enright

object named as

Anton J Enright

11

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object named as

Mark A Behlke

15

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William J Griffiths

object named as

William J Griffiths

19

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18

object named as

Lars Dölken

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author name string

Kevin A Robertson

1

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Wei Yuan Hsieh

2

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Mathieu Blanc

4

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Hongjin Lu

5

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Peter J Crick

6

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Steven Watterson

8

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Kimberly Martin

9

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Samantha J Griffiths

10

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Mami Yamamoto

12

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Madapura M Pradeepa

13

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Kimberly A Lennox

14

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Simon Talbot

16

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Jürgen Haas

17

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publication date

March 2016

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14

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3

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e1002364

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Creative Commons Attribution 4.0 International

3 March 2016

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April 2022 Public Data File from Crossref

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4777525/fullTextXML

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Europe PubMed Central

26 June 2022

https://europepmc.org/article/PMC/PMC4777525

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RNAi and antiviral defense in Drosophila: setting up a systemic immune response

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Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

1 reference

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Host defense against viral infection involves interferon mediated down-regulation of sterol biosynthesis

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19 March 2017

Interferon modulation of cellular microRNAs as an antiviral mechanism

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19 March 2017

MicroRNA-155 is induced during the macrophage inflammatory response

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Identification of miR-185 as a regulator of de novo cholesterol biosynthesis and low density lipoprotein uptake

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25-Hydroxycholesterol activates the integrated stress response to reprogram transcription and translation in macrophages

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29 September 2017

Lipids in innate antiviral defense

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29 September 2017

Antiviral RNA interference in mammalian cells

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RNA interference functions as an antiviral immunity mechanism in mammals

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29 September 2017

Sterols and oxysterols in immune cell function

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MicroRNA-185 and 342 inhibit tumorigenicity and induce apoptosis through blockade of the SREBP metabolic pathway in prostate cancer cells

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RNA interference-mediated intrinsic antiviral immunity in plants

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Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144.

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MiR-33 contributes to the regulation of cholesterol homeostasis.

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10.1371/JOURNAL.PBIO.1002364

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