(Q28577883)

31 January 2017

title

Activation of double-stranded RNA-activated protein kinase by mild impairment of oxidative metabolism in neurons (English)

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31 January 2017

Bingwei Wang

3

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Zun-Ji Ke

object named as

Zun-Ji Ke

5

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author name string

Xin Wang

1

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31 January 2017

Zhiqin Fan

2

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31 January 2017

Jia Luo

4

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31 January 2017

language of work or name

English

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publication date

1 December 2007

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Journal of Neurochemistry

31 January 2017

published in

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31 January 2017

volume

103

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31 January 2017

issue

6

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31 January 2017

page(s)

2380–2390

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Serine 18 phosphorylation of RAX, the PKR activator, is required for PKR activation and consequent translation inhibition

31 January 2017

cites work

1 reference

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The small leucine-rich proteoglycan biglycan modulates BMP-4-induced osteoblast differentiation

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Interaction between RAX and PKR modulates the effect of ethanol on protein synthesis and survival of neurons

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RAX, a cellular activator for double-stranded RNA-dependent protein kinase during stress signaling

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Ethanol inhibits brain-derived neurotrophic factor-mediated intracellular signaling and activator protein-1 activation in cerebellar granule neurons

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Translation inhibition in apoptosis: caspase-dependent PKR activation and eIF2-alpha phosphorylation

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PKR; a sentinel kinase for cellular stress

21 April 2017

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Developmental expression of matrix metalloproteinases 2 and 9 and their potential role in the histogenesis of the cerebellar cortex

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Neuronal loss in functional zones of the cerebellum of chronic alcoholics with and without Wernicke's encephalopathy

21 January 2018

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Activation of the dsRNA-dependent protein kinase, PKR, induces apoptosis through FADD-mediated death signaling

21 January 2018

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Double-strand RNA dependent protein kinase (PKR) is involved in the extrastriatal degeneration in Parkinson's disease and Huntington's disease

21 January 2018

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21 January 2018

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Involvement of double-stranded RNA-dependent protein kinase and phosphorylation of eukaryotic initiation factor-2alpha in neuronal degeneration

21 January 2018

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The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration

21 January 2018

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Induction of apoptosis by the dsRNA-dependent protein kinase (PKR): mechanism of action

21 January 2018

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Oxidative Damage to the Endoplasmic Reticulum is Implicated in Ischemic Neuronal Cell Death

21 January 2018

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Selective response of various brain cell types during neurodegeneration induced by mild impairment of oxidative metabolism

21 January 2018

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21 January 2018

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Ethanol induces cell death and cell cycle delay in cultures of pheochromocytoma PC12 cells

21 January 2018

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An RNA-dependent protein kinase is involved in tunicamycin-induced apoptosis and Alzheimer's disease

21 January 2018

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Metabolic impairment elicits brain cell type-selective changes in oxidative stress and cell death in culture.

21 January 2018

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Mitochondrial impairment in the cerebellum of the patients with progressive supranuclear palsy

21 January 2018

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PKR activation in neurodegenerative disease

21 January 2018

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Double-stranded RNA-dependent protein kinase, PKR, binds preferentially to Huntington's disease (HD) transcripts and is activated in HD tissue

21 January 2018

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Autophosphorylation in the activation loop is required for full kinase activity in vivo of human and yeast eukaryotic initiation factor 2alpha kinases PKR and GCN2

21 January 2018

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Ceramide regulates protein synthesis by a novel mechanism involving the cellular PKR activator RAX.

21 January 2018

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21 January 2018

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Inhibitor of double stranded RNA-dependent protein kinase protects against cell damage induced by ER stress

21 January 2018

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Molecular mechanisms of thiamine utilization

21 January 2018

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Upstream signaling pathways leading to the activation of double-stranded RNA-dependent serine/threonine protein kinase in beta-amyloid peptide neurotoxicity

21 January 2018

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The emerging role of the interferon-induced PKR protein kinase as an apoptotic effector: a new face of death?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04978.X

Heterologous dimerization domains functionally substitute for the double-stranded RNA binding domains of the kinase PKR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04978.X

Thiamine deficiency induces endoplasmic reticulum stress in neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04978.X

Tumor necrosis factor alpha (TNFalpha) induces the unfolded protein response (UPR) in a reactive oxygen species (ROS)-dependent fashion, and the UPR counteracts ROS accumulation by TNFalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04978.X

21 January 2018

ER stress and diseases.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04978.X

Endoplasmic reticulum stress in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04978.X

10.1111/J.1471-4159.2007.04978.X

21 January 2018

Identifiers

DOI

1 reference

31 January 2017

1 reference