(Q28580390)

31 January 2017

title

Bcl-2 transfection via herpes simplex virus blocks apoptosis-inducing factor translocation after focal ischemia in the rat (English)

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31 January 2017

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5

Robert M. Sapolsky

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31 January 2017

2

Midori A. Yenari

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31 January 2017

6

Gary K. Steinberg

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31 January 2017

Heng Zhao

1

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31 January 2017

Danye Cheng

series ordinal

3

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31 January 2017

Odmara L. Barreto-Chang

series ordinal

4

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31 January 2017

publication date

1 June 2004

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Journal of Cerebral Blood Flow & Metabolism

31 January 2017

published in

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31 January 2017

volume

24

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31 January 2017

issue

6

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31 January 2017

page(s)

681–692

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Bcl-2 protects from oxidative damage and apoptotic cell death without interfering with activation of NF-kappa B by TNF.

31 January 2017

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BCL-2 transduction, using a herpes simplex virus amplicon, protects hippocampal neurons from transient global ischemia

21 January 2018

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Mitochondrial release of AIF and EndoG requires caspase activation downstream of Bax/Bak-mediated permeabilization

21 January 2018

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Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli

21 January 2018

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Apoptosis-inducing factor mediates microglial and neuronal apoptosis caused by pneumococcus

21 January 2018

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Translocation of apoptosis-inducing factor in vulnerable neurons after transient cerebral ischemia and in neuronal cultures after oxygen-glucose deprivation

21 January 2018

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Cloning and characterization of rat caspase-9: implications for a role in mediating caspase-3 activation and hippocampal cell death after transient cerebral ischemia.

21 January 2018

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Reactive oxygen radicals in signaling and damage in the ischemic brain

21 January 2018

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Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death

21 January 2018

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Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis

21 January 2018

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Gene therapies that enhance hippocampal neuron survival after an excitotoxic insult are not equivalent in their ability to maintain synaptic transmission

21 January 2018

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A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

21 January 2018

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Bcl-2 and mitochondrial oxygen radicals. New approaches with reactive oxygen species-sensitive probes.

21 January 2018

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Signaling of Cell Death and Cell Survival Following Focal Cerebral Ischemia: Life and Death Struggle in the Penumbra

21 January 2018

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Bcl-2 decreases the free Ca2+ concentration within the endoplasmic reticulum

21 January 2018

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Cytosolic redistribution of cytochrome c after transient focal cerebral ischemia in rats.

21 January 2018

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Role of caspase-3 activation in cerebral ischemia-induced neurodegeneration in adult and neonatal brain

21 January 2018

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Programmed cell death in cerebral ischemia

21 January 2018

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Mitochondria and apoptosis

21 January 2018

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Relocalization of apoptosis-inducing factor in photoreceptor apoptosis induced by retinal detachment in vivo

21 January 2018

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SOD1 down-regulates NF-kappaB and c-Myc expression in mice after transient focal cerebral ischemia

21 January 2018

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A bcl-2 expressing viral vector protects cortical neurons from excitotoxicity even when administered several hours after the toxic insult.

21 January 2018

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Zn(2+) induces permeability transition pore opening and release of pro-apoptotic peptides from neuronal mitochondria.

21 January 2018

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Expression of bcl-2 inhibits necrotic neural cell death.

21 January 2018

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Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

21 January 2018

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The harlequin mouse mutation downregulates apoptosis-inducing factor

21 January 2018

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Bcl-2 prevents mitochondrial permeability transition and cytochrome c release via maintenance of reduced pyridine nucleotides.

21 January 2018

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Activation of membrane-associated procaspase-3 is regulated by Bcl-2.

21 January 2018

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Herpes simplex viral vectors expressing Bcl-2 are neuroprotective when delivered after a stroke

21 January 2018

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Apoptosis in the absence of caspase 3.

21 January 2018

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Expression of bcl-2 from a defective herpes simplex virus-1 vector limits neuronal death in focal cerebral ischemia

21 January 2018

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Is caspase-3 inhibition a valid therapeutic strategy in cerebral ischemia?

21 January 2018

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Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death

21 January 2018

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Induction of caspase-activated deoxyribonuclease activity after focal cerebral ischemia and reperfusion

21 January 2018

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Apoptosis after experimental stroke: fact or fashion?

21 January 2018

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Detection of higher-order 50- and 10-kbp DNA fragments before apoptotic internucleosomal cleavage after transient cerebral ischemia.

21 January 2018

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Optimal depth and duration of mild hypothermia in a focal model of transient cerebral ischemia: effects on neurologic outcome, infarct size, apoptosis, and inflammation

21 January 2018

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Apoptosis in neurodegenerative disorders

21 January 2018

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Sparing of neuronal function postseizure with gene therapy

21 January 2018

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NADH oxidase activity of mitochondrial apoptosis-inducing factor

21 January 2018

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Bcl-2 inhibits Bax translocation from cytosol to mitochondria during drug-induced apoptosis of human tumor cells.

21 January 2018

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Limitations in the neuroprotective potential of gene therapy with Bcl-2.

21 January 2018

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A role for calcium in Bcl-2 action?

21 January 2018

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BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia

21 January 2018

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Gene therapy using viral vectors for acute neurologic insults

21 January 2018

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Caspases as treatment targets in stroke and neurodegenerative diseases

21 January 2018

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Bcl-2 prevents apoptotic mitochondrial dysfunction by regulating proton flux

21 January 2018

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Mitochondrial release of caspase-2 and -9 during the apoptotic process

21 January 2018

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Molecular characterization of mitochondrial apoptosis-inducing factor

21 January 2018

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Bcl-2 family: life-or-death switch

21 January 2018

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DNA fragmentation in ischemic core and penumbra in focal cerebral ischemia in rats

21 January 2018

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Gene therapy with HSP72 is neuroprotective in rat models of stroke and epilepsy

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Mild hypothermia attenuates cytochrome c release but does not alter Bcl-2 expression or caspase activation after experimental stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Calbindin d28k overexpression protects striatal neurons from transient focal cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Both caspase-dependent and caspase-independent pathways may be involved in hippocampal CA1 neuronal death because of loss of cytochrome c From mitochondria in a rat forebrain ischemia model

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Inhibition of caspases inhibits the release of apoptotic bodies: Bcl-2 inhibits the initiation of formation of apoptotic bodies in chemotherapeutic agent-induced apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Intranuclear localization of apoptosis-inducing factor (AIF) and large scale DNA fragmentation after traumatic brain injury in rats and in neuronal cultures exposed to peroxynitrite.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Mild hypothermia increases Bcl-2 protein expression following global cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5

The machinery of programmed cell death.

21 January 2018

1 reference

https://api.crossref.org/works/10.1097%2F01.WCB.0000127161.89708.A5