(Q28590988)

31 January 2017

title

The tyrosine kinase Syk differentially regulates Toll-like receptor signaling downstream of the adaptor molecules TRAF6 and TRAF3 (English)

1 reference

31 January 2017

0 references

Spleen tyrosine kinase

1 reference

GOA release 2020-03-11

Ching-Liang Chu

3

0 references

Yi-Ling Lin

object named as

Yi-Ling Lin

4

0 references

author name string

Ying-Cing Lin

1

1 reference

31 January 2017

Duen-Yi Huang

2

1 reference

31 January 2017

Wan-Wan Lin

5

3

1 reference

15306813

31 January 2017

1 February 2017

publication date

20 August 2013

1 reference

31 January 2017

1 reference

31 January 2017

volume

6

1 reference

31 January 2017

issue

289

1 reference

31 January 2017

page(s)

ra71

1 reference

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

31 January 2017

cites work

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

CD14 controls the LPS-induced endocytosis of Toll-like receptor 4

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Microbe sensing, positive feedback loops, and the pathogenesis of inflammatory diseases

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Syk expression and novel function in a wide variety of tissues

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

The SYK side of TLR4: signalling mechanisms in response to LPS and minimally oxidized LDL

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

A critical role for Syk in signal transduction and phagocytosis mediated by Fcgamma receptors on macrophages

21 April 2017

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003973

Regulation and function of NF-kappaB transcription factors in the immune system

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Functional evolution of the TICAM-1 pathway for extrinsic RNA sensing.

21 April 2017

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Genetic analysis of host resistance: Toll-like receptor signaling and immunity at large

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Regulation of lipopolysaccharide-inducible genes by MyD88 and Toll/IL-1 domain containing adaptor inducing IFN-β

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

A cell biological view of Toll-like receptor function: regulation through compartmentalization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Different modes of ubiquitination of the adaptor TRAF3 selectively activate the expression of type I interferons and proinflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Ubiquitylation in innate and adaptive immunity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

21 January 2018

The many faces of ITAMs.

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Spleen tyrosine kinase: an Src family of non-receptor kinase has multiple functions and represents a valuable therapeutic target in the treatment of autoimmune and inflammatory diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Inhibition of immune responses by ITAM-bearing receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

The SYK tyrosine kinase: a crucial player in diverse biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Poly(I:C) induces BLyS-expression of airway fibroblasts through phosphatidylinositol 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Lipoprotein accumulation in macrophages via toll-like receptor-4-dependent fluid phase uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

CpG-induced tyrosine phosphorylation occurs via a TLR9-independent mechanism and is required for cytokine secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Involvement of Syk protein tyrosine kinase in LPS-induced responses in macrophages.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Anti-inflammatory actions of Syk inhibitors in macrophages involve non-specific inhibition of toll-like receptors-mediated JNK signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Spleen tyrosine kinase regulates AP-1 dependent transcriptional response to minimally oxidized LDL

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Involvement of Syk kinase in TNF-induced nitric oxide production by airway epithelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Lipopolysaccharide-induced c-Jun NH2-terminal kinase activation in human neutrophils: role of phosphatidylinositol 3-Kinase and Syk-mediated pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Enhanced Toll-like receptor responses in the absence of signaling adaptor DAP12.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Increased TLR responses in dendritic cells lacking the ITAM-containing adapters DAP12 and FcRgamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Lipopolysaccharide interaction with cell surface Toll-like receptor 4-MD-2: higher affinity than that with MD-2 or CD14.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

Conventional dendritic cells mount a type I IFN response against Candida spp. requiring novel phagosomal TLR7-mediated IFN-β signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

MyD88 drives the IFN-β response to Lactobacillus acidophilus in dendritic cells through a mechanism involving IRF1, IRF3, and IRF7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973

NF-κB-mediated degradation of the coactivator RIP140 regulates inflammatory responses and contributes to endotoxin tolerance

21 January 2018

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003973