(Q28592943)

English

Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN

scientific journal article

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scholarly article

1 reference

PubMed publication ID

31 January 2017

Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN (English)

1 reference

PubMed publication ID

31 January 2017

Androgen receptor

1 reference

GOA release 2020-03-11

Antigen identified by monoclonal antibody Ki 67

1 reference

GOA release 2020-03-11

SRY (sex determining region Y)-box 9

1 reference

GOA release 2020-03-11

Thymoma viral proto-oncogene 1

1 reference

GOA release 2020-03-11

Inhibitor of DNA binding 4

1 reference

GOA release 2020-03-11

author name string

Pankaj Sharma

1

1 reference

PubMed publication ID

31 January 2017

Ashley Evans Knowell

2

1 reference

PubMed publication ID

31 January 2017

Swathi Chinaranagari

3

1 reference

PubMed publication ID

31 January 2017

Shravan Komaragiri

4

1 reference

PubMed publication ID

31 January 2017

Peri Nagappan

5

1 reference

PubMed publication ID

31 January 2017

Divya Patel

6

1 reference

PubMed publication ID

31 January 2017

Mathew C. Havrda

7

1 reference

PubMed publication ID

31 January 2017

Jaideep Chaudhary

8

1 reference

PubMed publication ID

31 January 2017

publication date

21 June 2013

1 reference

PubMed publication ID

31 January 2017

Molecular Cancer

1 reference

PubMed publication ID

31 January 2017

12

1 reference

PubMed publication ID

31 January 2017

67

1 reference

PubMed publication ID

31 January 2017

NIH Image to ImageJ: 25 years of image analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

MYC cooperates with AKT in prostate tumorigenesis and alters sensitivity to mTOR inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

SOX9 induces and maintains neural stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id4, a new candidate gene for senile osteoporosis, acts as a molecular switch promoting osteoblast differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Inhibitor of DNA binding 4 (ID4) regulation of adipocyte differentiation and adipose tissue formation in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Promoter methylation-associated loss of ID4 expression is a marker of tumour recurrence in human breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Increased prostate cell proliferation and loss of cell differentiation in mice lacking prostate epithelial androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Hedgehog pathway activity in the LADY prostate tumor model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Disruption of prostate epithelial androgen receptor impedes prostate lobe-specific growth and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id4 is required for the correct timing of neural differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Amplification and overexpression of the ID4 gene at 6p22.3 in bladder cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id4 regulates neural progenitor proliferation and differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id4 regulates mammary epithelial cell growth and differentiation and is overexpressed in rat mammary gland carcinomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id proteins in development, cell cycle and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Growth retardation and increased apoptosis in mice with homozygous disruption of the Akt1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

p63 is a prostate basal cell marker and is required for prostate development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Roles for Nkx3.1 in prostate development and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

17 March 2017

Id1 and Id3 expression is associated with increasing grade of prostate cancer: Id3 preferentially regulates CDKN1B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Epigenetic inactivation of inhibitor of differentiation 4 (Id4) correlates with prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Chromatin immunoprecipitation and high-throughput sequencing from paraffin-embedded pathology tissue

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

ID4 regulates mammary gland development by suppressing p38MAPK activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

ID4 is frequently downregulated and partially hypermethylated in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Inhibitor of DNA binding 4 is expressed selectively by single spermatogonia in the male germline and regulates the self-renewal of spermatogonial stem cells in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Intronic DNA elements regulate androgen-dependent expression of the murine Nkx3.1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Silencing of the inhibitor of DNA binding protein 4 (ID4) contributes to the pathogenesis of mouse and human CLL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Repression of Id2 expression by Gfi-1 is required for B-cell and myeloid development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Molecular insights into androgen actions in male and female reproductive function from androgen receptor knockout models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Inhibitor of differentiation 1 (ID1) promotes cell survival and proliferation of prostate epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Inhibitor of differentiation 4 (Id4) is a potential tumor suppressor in prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Id3 restricts the developmental potential of gamma delta lineage during thymopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

The role of Sox9 in prostate development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Molecular signaling pathways that regulate prostate gland development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

SOX9 is expressed in human fetal prostate epithelium and enhances prostate cancer invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

ID1-, ID2-, and ID3-regulated gene expression in E2A positive or negative prostate cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/- mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Non-redundant inhibitor of differentiation (Id) gene expression and function in human prostate epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Mechanisms of prostate tumorigenesis: roles for transcription factors Nkx3.1 and Egr1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

The corepressors silencing mediator of retinoid and thyroid hormone receptor and nuclear receptor corepressor are involved in agonist- and antagonist-regulated transcription by androgen receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Androgens regulate the immune/inflammatory response and cell survival pathways in rat ventral prostate epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Epigenetic inactivation of ID4 in colorectal carcinomas correlates with poor differentiation and unfavorable prognosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

A role for Id proteins in mammary gland physiology and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Id-1 and Id-2 proteins as molecular markers for human prostate cancer progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Prostate pathology of genetically engineered mice: definitions and classification. The consensus report from the Bar Harbor meeting of the Mouse Models of Human Cancer Consortium Prostate Pathology Committee.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Downregulation of ID4 by promoter hypermethylation in gastric adenocarcinoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Id4 is deregulated by a t(6;14)(p22;q32) chromosomal translocation in a B-cell lineage acute lymphoblastic leukemia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Id proteins in cell growth and tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Id proteins in epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Id1 regulation of cellular senescence through transcriptional repression of p16/Ink4a.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

ID helix-loop-helix proteins in cell growth, differentiation and tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

The Id4 HLH protein and the timing of oligodendrocyte differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Impaired immune responses and B-cell proliferation in mice lacking the Id3 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Regulation of the expression of cyclin-dependent kinase inhibitor p21 by E2A and Id proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

29 September 2017

Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

3 June 2018

Prostate-specific and androgen-dependent expression of a novel homeobox gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

3 June 2018

Expression of Id2 in the second heart field and cardiac defects in Id2 knock-out mice.

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome.

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

Aberrant hypermethylation of ID4 gene promoter region increases risk of lymph node metastasis in T1 breast cancer.

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

t(6;14)(p22;q32): a new recurrent IGH@ translocation involving ID4 in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss.

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

Id proteins facilitate self-renewal and proliferation of neural stem cells

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

Androgen sensitivity of prostate epithelium is enhanced by postnatal androgen receptor inactivation

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

Myc-driven murine prostate cancer shares molecular features with human prostate tumors

1 reference

https://api.crossref.org/works/10.1186%2F1476-4598-12-67

21 January 2018

Nkx3.1; Pten mutant mice develop invasive prostate adenocarcinoma and lymph node metastases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

27 November 2018

Increased c-myc oncogene expression in Ewing's sarcoma: correlation with Ki67 proliferation index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

27 November 2018

Id helix-loop-helix proteins in cell growth and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3694449

27 November 2018

Id2 controls chondrogenesis acting downstream of BMP signaling during maxillary morphogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23786676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibitor of DNA binding-1 overexpression in prostate cancer: relevance to tumor differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/23786676

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/1476-4598-12-67

1 reference

PubMed publication ID

31 January 2017

Dimensions Publication ID

0 references

PMC publication ID

0 references

PubMed publication ID

1 reference

PubMed publication ID

31 January 2017

ResearchGate publication ID

0 references

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