(Q28593518)

GOA release 2020-03-11

Sonic hedgehog

1 reference

GOA release 2020-03-11

6

Andrew P. McMahon

1 reference

31 January 2017

Gabriel D. Dakubo

1

1 reference

31 January 2017

Chantal Mazerolle

2

1 reference

31 January 2017

Marosh Furimsky

3

1 reference

31 January 2017

Chuan Yu

4

1 reference

31 January 2017

Benoit St-Jacques

5

1 reference

31 January 2017

Valerie A. Wallace

The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal

7

1 reference

31 January 2017

language of work or name

English

0 references

publication date

1 August 2008

1 reference

31 January 2017

Developmental Biology

1 reference

31 January 2017

320

1 reference

31 January 2017

1

1 reference

31 January 2017

242–255

1 reference

31 January 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog signaling in vertebrate eye development: a growing puzzle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Defects in the MITF(mi/mi) apical surface are associated with a failure of outer segment elongation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog signaling in murine vasculogenesis and angiogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Crx, a novel Otx-like paired-homeodomain protein, binds to and transactivates photoreceptor cell-specific genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Fate maps of neural crest and mesoderm in the mammalian eye.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog and patched in neural development and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Expression of the mouse Fkh1/Mf1 and Mfh1 genes in late gestation embryos is restricted to mesoderm derivatives.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

A mouse model of greig cephalopolysyndactyly syndrome: the extra-toesJ mutation contains an intragenic deletion of the Gli3 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The patched gene in development and cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog signaling in animal development: paradigms and principles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Compound developmental eye disorders following inactivation of TGFbeta signaling in neural-crest stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog signaling in the neural crest cells regulates the patterning and growth of facial primordia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Sonic hedgehog induces capillary morphogenesis by endothelial cells through phosphoinositide 3-kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Staggered cell-intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Fibroblast growth factor signals regulate a wave of Hedgehog activation that is essential for coronary vascular development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Inductive effects of the retinal pigmented epithelium (RPE) on histogenesis of the avian retina as revealed by retinospheroid technology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Sonic hedgehog promotes rod photoreceptor differentiation in mammalian retinal cells in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Pitx2 regulates lung asymmetry, cardiac positioning and pituitary and tooth morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Specification of ventral neuron types is mediated by an antagonistic interaction between Shh and Gli3

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Characterization of Wnt signaling components and activation of the Wnt canonical pathway in the murine retina.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog signaling and the retina: insights into the mechanisms controlling the proliferative properties of neural precursors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Function of Rieger syndrome gene in left-right asymmetry and craniofacial development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Biochemical evidence that patched is the Hedgehog receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The hedgehog-PKA pathway regulates two distinct steps of the differentiation of retinal ganglion cells: the cell-cycle exit of retinoblasts and their neuronal maturation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Retinoic acid-dependent eye morphogenesis is orchestrated by neural crest cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Quantitative and morphological changes of the choroid vasculature in RCS rats and their congenic controls

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Sonic hedgehog regulates proliferation of the retinal ciliary marginal zone in posthatch chicks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Sonic hedgehog signaling by the patched-smoothened receptor complex

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Patterning of the zebrafish retina by a wave of sonic hedgehog activity.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

ATP released via gap junction hemichannels from the pigment epithelium regulates neural retinal progenitor proliferation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

A novel function for Hedgehog signalling in retinal pigment epithelium differentiation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The morphogen Sonic hedgehog is an indirect angiogenic agent upregulating two families of angiogenic growth factors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The retinal pigmented epithelium is required for development and maintenance of the mouse neural retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Neural and angiogenic defects in eyes of transgenic mice expressing a dominant-negative FGF receptor in the pigmented cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Involvement of fibroblast growth factors in choroidal angiogenesis and retinal vascularization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Vessel formation by choroidal endothelial cells in vitro is modulated by retinal pigment epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Shh directs cell-cycle exit by activating p57Kip2 in the zebrafish retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Sonic hedgehog, secreted by amacrine cells, acts as a short-range signal to direct differentiation and lamination in the zebrafish retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Cloning and expression pattern of chicken Pitx2: a new component in the SHH signaling pathway controlling embryonic heart looping.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Extraretinal and retinal hedgehog signaling sequentially regulate retinal differentiation in zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Function for Hedgehog genes in zebrafish retinal development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Embryonic retinal gene expression in sonic-you mutant zebrafish

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Inhibition of ocular neovascularization by hedgehog blockade.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog and patched gene expression in adult ocular tissues.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

'Smoothening' the path for hedgehogs.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Angiogenic factors stimulate tubular branching morphogenesis of sonic hedgehog-deficient lungs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Hedgehog signaling is essential for endothelial tube formation during vasculogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Development of normal retinal organization depends on Sonic hedgehog signaling from ganglion cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Retinal ganglion cell-derived sonic hedgehog locally controls proliferation and the timing of RGC development in the embryonic mouse retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

The winged helix transcription factor MFH1 is required for proliferation and patterning of paraxial mesoderm in the mouse embryo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Müller glia endfeet, a basal lamina and the polarity of retinal layers form properly in vitro only in the presence of marginal pigmented epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Tbx1 is regulated by tissue-specific forkhead proteins through a common Sonic hedgehog-responsive enhancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Pitx2, a bicoid-type homeobox gene, is involved in a lefty-signaling pathway in determination of left-right asymmetry

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528

Temporal and spatial effects of Sonic hedgehog signaling in chick eye morphogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.05.528