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Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
title
Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2
(English)
1 reference
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
author
Joshua Curry
series ordinal
2
1 reference
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
author name string
Hae J Park
series ordinal
1
1 reference
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
James A McCormick
series ordinal
3
1 reference
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
language of work or name
English
1 reference
based on heuristic
inferred from title
publication date
15 December 2013
1 reference
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
published in
American Journal of Physiology - Renal Physiology
2 references
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
volume
305
2 references
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
page(s)
F1687-96
1 reference
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
issue
12
2 references
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
cites work
A SPAK isoform switch modulates renal salt transport and blood pressure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
Bartter- and Gitelman-like syndromes: salt-losing tubulopathies with loop or DCT defects
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
Activation of the thiazide-sensitive Na+-Cl- cotransporter by the WNK-regulated kinases SPAK and OSR1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
WNK1 and OSR1 regulate the Na+, K+, 2Cl- cotransporter in HeLa cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
Functional interactions of the SPAK/OSR1 kinases with their upstream activator WNK1 and downstream substrate NKCC1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
PASK (Proline-Alanine-rich STE20-related Kinase), a Regulatory Kinase of the Na-K-Cl Cotransporter (NKCC1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
17 March 2017
SPAK differentially mediates vasopressin effects on sodium cotransporters.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Molecular physiology of SPAK and OSR1: two Ste20-related protein kinases regulating ion transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Effects of K+-deficient diets with and without NaCl supplementation on Na+, K+, and H2O transporters' abundance along the nephron
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Impaired phosphorylation of Na(+)-K(+)-2Cl(-) cotransporter by oxidative stress-responsive kinase-1 deficiency manifests hypotension and Bartter-like syndrome
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Recruitment interactions can override catalytic interactions in determining the functional identity of a protein kinase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
The WNKs: atypical protein kinases with pleiotropic actions.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
On the substrate recognition and negative regulation of SPAK, a kinase modulating Na+-K+-2Cl- cotransport activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Role of the WNK-activated SPAK kinase in regulating blood pressure
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
The regulation of salt transport and blood pressure by the WNK-SPAK/OSR1 signalling pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Regulation of NKCC2 by a chloride-sensing mechanism involving the WNK3 and SPAK kinases
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Cotransporters, WNKs and hypertension: an update
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Properties of WNK1 and implications for other family members
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Molecular physiology and pathophysiology of electroneutral cation-chloride cotransporters.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
29 September 2017
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3882447
retrieved
3 June 2018
Regulatory phosphorylation sites in the NH2 terminus of the renal Na-K-Cl cotransporter (NKCC2).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1152%2FAJPRENAL.00211.2013
retrieved
21 January 2018
Characterization of a Na(+)-K(+)-2Cl- cotransport system in oocytes from Xenopus laevis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24133122
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1152/AJPRENAL.00211.2013
2 references
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
PMCID
3882447
1 reference
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
PubMed ID
24133122
2 references
stated in
PubMed
PubMed ID
24133122
retrieved
31 January 2017
stated in
Mili Akhtar
PMCID
3882447
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24133122%20AND%20SRC:MED&resulttype=core&format=json
retrieved
2 June 2020
ResearchGate publication ID
257889710
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