(Q28593809)

31 January 2017

title

Increased striatal dopamine release and hyperdopaminergic-like behaviour in mice lacking both alpha-synuclein and gamma-synuclein (English)

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31 January 2017

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1 reference

GOA release 2020-03-11

Synuclein, gamma

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GOA release 2020-03-11

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1 reference

Stephanie J. Cragg

6

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Richard Wade-Martins

object named as

Richard Wade-Martins

7

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David M Bannerman

object named as

David Bannerman

4

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author name string

Steven L. Senior

1

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31 January 2017

Natalia Ninkina

2

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31 January 2017

Robert Deacon

3

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31 January 2017

Vladimir L. Buchman

5

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31 January 2017

language of work or name

English

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publication date

1 February 2008

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European Journal of Neuroscience

31 January 2017

published in

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31 January 2017

volume

27

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31 January 2017

issue

4

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31 January 2017

page(s)

947–957

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Alpha-synuclein inhibits aromatic amino acid decarboxylase activity in dopaminergic cells

31 January 2017

cites work

1 reference

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Double-knockout mice for alpha- and beta-synucleins: effect on synaptic functions

17 March 2017

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Developmental loss and resistance to MPTP toxicity of dopaminergic neurones in substantia nigra pars compacta of gamma-synuclein, alpha-synuclein and double alpha/gamma-synuclein null mutant mice

17 March 2017

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Distribution of α‐ and γ‐synucleins in the adult rat brain and their modification by high‐dose cocaine treatment

17 March 2017

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alpha-Synuclein locus triplication causes Parkinson's disease

17 March 2017

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Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the Gene

17 March 2017

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Modulation of dopamine transporter function by alpha-synuclein is altered by impairment of cell adhesion and by induction of oxidative stress

17 March 2017

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Synaptic vesicle depletion correlates with attenuated synaptic responses to prolonged repetitive stimulation in mice lacking alpha-synuclein

17 March 2017

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Differential localization of alpha-, beta- and gamma-synucleins in the rat CNS

17 March 2017

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A role for alpha-synuclein in the regulation of dopamine biosynthesis

17 March 2017

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Mice lacking alpha-synuclein display functional deficits in the nigrostriatal dopamine system

17 March 2017

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

17 March 2017

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Mutation in the alpha-synuclein gene identified in families with Parkinson's disease

17 March 2017

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Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter

17 March 2017

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The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia

17 March 2017

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Alpha-synuclein locus duplication as a cause of familial Parkinson's disease

7 April 2017

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Definition of the readily releasable pool of vesicles at hippocampal synapses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

RNA interference-mediated knockdown of alpha-synuclein protects human dopaminergic neuroblastoma cells from MPP(+) toxicity and reduces dopamine transport.

7 April 2017

1 reference

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Alpha-synuclein activation of protein phosphatase 2A reduces tyrosine hydroxylase phosphorylation in dopaminergic cells

29 September 2017

1 reference

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Attenuation of dopamine transporter activity by alpha-synuclein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP.

29 September 2017

1 reference

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Functional domains in dorsal striatum of the nonhuman primate are defined by the dynamic behavior of dopamine.

29 September 2017

1 reference

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Direct binding and functional coupling of alpha-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis.

29 September 2017

1 reference

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Hyperactivity and impaired response habituation in hyperdopaminergic mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Dopamine release and uptake dynamics within nonhuman primate striatum in vitro.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Association between preference for sweets and excessive alcohol intake: a review of animal and human studies

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Identification of two distinct synucleins from human brain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Whole genome expression analyses of single- and double-knock-out mice implicate partially overlapping functions of alpha- and gamma-synuclein.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

The ultrastructural distribution of alpha-synuclein-like protein in normal mouse brain

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Variable dopamine release probability and short-term plasticity between functional domains of the primate striatum.

3 June 2018

1 reference

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Saccharin intake predicts ethanol intake in genetically heterogeneous rats as well as different rat strains.

3 June 2018

1 reference

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Amphetamine-elicited perseverative and rotational behavior: evaluation of directional preference

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Dissociation of the effects of scopolamine and d-amphetamine on a spontaneous alternation task

3 June 2018

1 reference

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Interaction between cholinergic and catecholaminergic agents in a spontaneous alternation task

3 June 2018

1 reference

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A comparison of GluR-A-deficient and wild-type mice on a test battery assessing sensorimotor, affective, and cognitive behaviors

3 June 2018

1 reference

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Alpha-synuclein protein levels are increased in alcoholic patients and are linked to craving

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Joint analysis of the NACP-REP1 marker within the alpha synuclein gene concludes association with alcohol dependence

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Elevated alpha synuclein mRNA levels are associated with craving in patients with alcoholism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Effects of cytotoxic hippocampal lesions in mice on a cognitive test battery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Hippocampal cytotoxic lesion effects on species-typical behaviours in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

T-maze alternation in the rodent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Neural activity controls the synaptic accumulation of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Lipid rafts mediate the synaptic localization of alpha-synuclein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Early behavioural changes in scrapie-affected mice and the influence of dapsone

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Familial parkinsonism with synuclein pathology: clinical and PET studies of A30P mutation carriers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

A combinatorial code for the interaction of alpha-synuclein with membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Phenotypic expression of the targeted null-mutation in the dopamine transporter gene varies as a function of the genetic background

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Brain reward in the absence of alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Cocaine abuse elevates alpha-synuclein and dopamine transporter levels in the human striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Nicotine amplifies reward-related dopamine signals in striatum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Deletion of glutamate receptor-A (GluR-A) AMPA receptor subunits impairs one-trial spatial memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Locomotor activity and evoked dopamine release are reduced in mice overexpressing A30P-mutated human alpha-synuclein

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Role of alpha-synuclein in presynaptic dopamine recruitment.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1460-9568.2008.06055.X

Cocaine abusers have an overexpression of alpha-synuclein in dopamine neurons.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145106

Synaptic Concentration of Dopamine in the Mouse Striatum in Relationship to the Kinetic Properties of the Dopamine Receptors and Uptake Mechanism

27 November 2018

1 reference

12 December 2020

Localization of alpha-synuclein to identified fibers and synapses in the normal mouse brain

1 reference

12 December 2020

A new brain-specific 14-kDa protein is a phosphoprotein. Its complete amino acid sequence and evidence for phosphorylation

1 reference

12 December 2020

Saccharin-induced increase in daily fluid intake as a predictor of voluntary alcohol intake in alcohol-preferring rats

1 reference

12 December 2020

Alpha-synuclein overexpression in PC12 and chromaffin cells impairs catecholamine release by interfering with a late step in exocytosis

1 reference

12 December 2020

10.1111/J.1460-9568.2008.06055.X

Identifiers

DOI

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