(Q28602444)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Agent-Based Modeling in Systems Pharmacology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Kieran Alden

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Mark N Read

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Jon Timmis

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

J Butler

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

V Kumar

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

L Cucurull-Sanchez

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

M Coles

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

13 November 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

CPT: pharmacometrics & systems pharmacology

5 March 2020

published in

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

615-629

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

Determining disease intervention strategies using spatially resolved simulations

5 March 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Effective visualization of integrated knowledge and data to enable informed decisions in drug development and translational medicine

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Modeling and simulation at the interface of nonclinical and early clinical drug development

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Agent-based modeling: a systematic assessment of use cases and requirements for enhancing pharmaceutical research and development productivity

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Hypoxia-inducing factors as master regulators of stemness properties and altered metabolism of cancer- and metastasis-initiating cells

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

A whole-cell computational model predicts phenotype from genotype

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Drug development: Raise standards for preclinical cancer research

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

The case for open computer programs

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

FDA Advisory Meeting Clinical Pharmacology Review Utilizes a Quantitative Systems Pharmacology (QSP) Model: A Watershed Moment?

17 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Implementation of quantitative and systems pharmacology in large pharma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Enabling multiscale modeling in systems medicine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Clonal and cellular dynamics in germinal centers

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Hybrid equation/agent-based model of ischemia-induced hyperemia and pressure ulcer formation predicts greater propensity to ulcerate in subjects with spinal cord injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Spartan: a comprehensive tool for understanding uncertainty in simulations of biological systems

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

A tumor hypoxic niche protects human colon cancer stem cells from chemotherapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Systems-pharmacology dissection of a drug synergy in imatinib-resistant CML.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Mechanistic systems modeling to guide drug discovery and development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

State-transition diagrams for biologists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Systems biology approaches for understanding cellular mechanisms of immunity in lymph nodes during infection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Teplizumab for treatment of type 1 diabetes (Protégé study): 1-year results from a randomised, placebo-controlled trial

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Multi-scale modelling and simulation in systems biology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Virtual optimization of nasal insulin therapy predicts immunization frequency to be crucial for diabetes protection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Agent-based models in translational systems biology.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Next-generation model-based drug discovery and development: quantitative and systems pharmacology

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Agent-based modeling of host-pathogen systems: The successes and challenges

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Autoimmune T cell responses in the central nervous system

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Germinal centres seen through the mathematical eye: B-cell models on the catwalk

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Synergy between individual TNF-dependent functions determines granuloma performance for controlling Mycobacterium tuberculosis infection.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Agent-based model of therapeutic adipose-derived stromal cell trafficking during ischemia predicts ability to roll on P-selectin.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Characterizing emergent properties of immunological systems with multi-cellular rule-based computational modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

A patient-specific in silico model of inflammation and healing tested in acute vocal fold injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

A methodology for performing global uncertainty and sensitivity analysis in systems biology.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

The origin and application of experimental autoimmune encephalomyelitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Combining experiments with multi-cell agent-based modeling to study biological tissue patterning

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Model-based drug development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Homeostatic control of immunity by TCR peptide-specific Tregs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

In silico experiments of existing and hypothetical cytokine-directed clinical trials using agent-based modeling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Agent-based computational modeling of wounded epithelial cell monolayers.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Simulating complex intracellular processes using object-oriented computational modelling.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

An integrative model of regulation centered on recognition of TCR peptide/MHC complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Clinical trial simulation in drug development

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Using argument notation to engineer biological simulations with increased confidence.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Pairing experimentation and computational modeling to understand the role of tissue inducer cells in the development of lymphoid organs.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Simulating Brain Tumor Heterogeneity with a Multiscale Agent-Based Model: Linking Molecular Signatures, Phenotypes and Expansion Rate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

Learning versus confirming in clinical drug development

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4716580

An analysis of B cell selection mechanisms in germinal centers.

3 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

The effects of EGF-receptor density on multiscale tumor growth patterns.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

A hybrid cellular automaton model of solid tumor growth and bioreductive drug transport.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

A standard protocol for describing individual-based and agent-based models

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

A mathematical framework for agent based models of complex biological networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

Spontaneous remission of autoimmune encephalomyelitis is inhibited by splenectomy, thymectomy or ageing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPSP4.12018

Model-Based Drug Development: A Rational Approach to Efficiently Accelerate Drug Development

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26783498

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Translational systems biology using an agent-based approach for dynamic knowledge representation: An evolutionary paradigm for biomedical research

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26783498

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impact of modeling and simulation: myth or fact?

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26783498

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/PSP4.12018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26783498%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

26783498

1 reference