(Q28609098)

3 February 2017

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Europe PubMed Central

title

Intracellular signaling by the neural cell adhesion molecule (English)

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3 February 2017

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Gro Klitgaard Povlsen

1

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3 February 2017

Dorte Kornerup Ditlevsen

2

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3 February 2017

Vladimir Berezin

3

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3 February 2017

Elisabeth Bock

4

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3 February 2017

publication date

1 January 2003

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3 February 2017

published in

Neurochemical Research

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3 February 2017

volume

28

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3 February 2017

issue

1

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3 February 2017

page(s)

127–141

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Neurite guidance molecules

3 February 2017

cites work

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12 December 2020

Reduced activation of RAF-1 and MAP kinase by a fibroblast growth factor receptor mutant deficient in stimulation of phosphatidylinositol hydrolysis

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12 December 2020

Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

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12 December 2020

Fibroblast growth factor receptor signaling in Xenopus retinal axon extension

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12 December 2020

Ca2+ influx and neurite growth in response to purified N-cadherin and laminin

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12 December 2020

Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase

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12 December 2020

p38 mitogen-activated protein kinase activation is required for fibroblast growth factor-2-stimulated cell proliferation but not differentiation

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12 December 2020

Cellular signaling by neural cell adhesion molecules of the immunoglobulin superfamily

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12 December 2020

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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12 December 2020

The neural cell adhesion molecule (NCAM) in development and plasticity of the nervous system

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12 December 2020

Nerve growth factor in combination with second messenger analogues causes neuronal differentiation of PC12 cells expressing a dominant inhibitory Ras protein without inducing activation of extracellular signal-regulated kinases

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12 December 2020

Mutations in the cell adhesion molecule L1 cause mental retardation

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12 December 2020

The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility.

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12 December 2020

A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation

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12 December 2020

Fibroblast growth factor receptors have different signaling and mitogenic potentials

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12 December 2020

NCAM stimulates the Ras-MAPK pathway and CREB phosphorylation in neuronal cells

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12 December 2020

PKC activators (phorbol ester or bryostatin) stimulate outgrowth of NGF-dependent neurites in a subline of PC12 cells

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12 December 2020

p59fyn and pp60c-src modulate axonal guidance in the developing mouse olfactory pathway

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12 December 2020

The transcription factors CREB and c-Fos play key roles in NCAM-mediated neuritogenesis in PC12-E2 cells

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12 December 2020

NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)

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12 December 2020

Cadherins: molecular codes for axon guidance and synapse formation

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12 December 2020

Rap1 signalling: adhering to new models

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12 December 2020

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

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12 December 2020

The production of arachidonic acid can account for calcium channel activation in the second messenger pathway underlying neurite outgrowth stimulated by NCAM, N-cadherin, and L1.

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12 December 2020

Identification of regulatory phosphorylation sites in mitogen-activated protein kinase (MAPK)-activated protein kinase-1a/p90rsk that are inducible by MAPK

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12 December 2020

FRS2 proteins recruit intracellular signaling pathways by binding to diverse targets on fibroblast growth factor and nerve growth factor receptors

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12 December 2020

Differentiation of PC12 cells in response to a cAMP analogue is accompanied by sustained activation of mitogen-activated protein kinase. Comparison with the effects of insulin, growth factors and phorbol esters

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12 December 2020

Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation

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12 December 2020

Correlation between changes in intracellular level of cyclic AMP, activation of cyclic AMP-dependent protein kinase, and the morphology of Chinese hamster ovary cells in culture

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12 December 2020

Identification of an amino acid sequence motif in the cytoplasmic domain of the NCAM-140 kDa isoform essential for its neuritogenic activity.

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12 December 2020

Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides.

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12 December 2020

Regulation of retinal neurite growth by alterations in MAPK/ERK kinase (MEK) activity

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12 December 2020

Brain specific synaptosomal membrane proteins demonstrated by crossed immunoelectrophoresis.

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12 December 2020

Direct activation of second messenger pathways mimics cell adhesion molecule-dependent neurite outgrowth

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12 December 2020

A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway

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12 December 2020

Arachidonic acid both inhibits and enhances whole cell calcium currents in rat sympathetic neurons

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12 December 2020

The 180-kD component of the neural cell adhesion molecule N-CAM is involved in cell-cell contacts and cytoskeleton-membrane interactions

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12 December 2020

Inhibition of FGF-stimulated phosphatidylinositol hydrolysis and neurite outgrowth by a cell-membrane permeable phosphopeptide

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12 December 2020

Mitogen- and stress-activated protein kinase-1 (MSK1) is directly activated by MAPK and SAPK2/p38, and may mediate activation of CREB

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12 December 2020

Neural cell adhesion molecule (N-CAM) domains and intracellular signaling pathways involved in the inhibition of astrocyte proliferation

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12 December 2020

Activation of mitogen-activated protein kinases is not required for the extension of neurites from PC12D cells triggered by nerve growth factor.

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12 December 2020

The neural cell adhesion molecule

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12 December 2020

Identification of a peptide sequence involved in homophilic binding in the neural cell adhesion molecule NCAM

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12 December 2020

The neural cell adhesion molecule in synaptic plasticity and ageing

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12 December 2020

Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation

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12 December 2020

Calphostin C induces tyrosine dephosphorylation/inactivation of protein kinase FA/GSK-3 alpha in a pathway independent of tumor promoter phorbol ester-mediated down-regulation of protein kinase C

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12 December 2020

A short segment within the cytoplasmic domain of the neural cell adhesion molecule (N-CAM) is essential for N-CAM-induced NF-kappa B activity in astrocytes

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12 December 2020

Turning of nerve growth cones induced by localized increases in intracellular calcium ions

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12 December 2020

Solution structure of the third immunoglobulin domain of the neural cell adhesion molecule N-CAM: can solution studies define the mechanism of homophilic binding?

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12 December 2020

NF-kappaB activation by N-CAM and cytokines in astrocytes is regulated by multiple protein kinases and redox modulation

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12 December 2020

Neurite outgrowth induced by a synthetic peptide ligand of neural cell adhesion molecule requires fibroblast growth factor receptor activation

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12 December 2020

A soluble chimeric form of the L1 glycoprotein stimulates neurite outgrowth

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12 December 2020

Induction of neuronal differentiation by a peptide corresponding to the homophilic binding site of the second Ig module of the neural cell adhesion molecule

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12 December 2020

Distinct neurite outgrowth signaling pathways converge on ERK activation

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12 December 2020

Increased intracellular calcium is required for neurite outgrowth induced by a synthetic peptide ligand of NCAM.

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12 December 2020

Structural basis of cell-cell adhesion by NCAM

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12 December 2020

The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus

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12 December 2020

Signal-transducing protein phosphorylation cascades mediated by Ras/Rho proteins in the mammalian cell: the potential for multiplex signalling

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12 December 2020

cAMP-dependent protein kinase induces cAMP-response element-binding protein phosphorylation via an intracellular calcium release/ERK-dependent pathway in striatal neurons.

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12 December 2020

Overexpression of Ca2+/calmodulin-dependent protein kinase II inhibits neurite outgrowth of PC12 cells

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12 December 2020

PC12 cell neuronal differentiation is associated with prolonged p21ras activity and consequent prolonged ERK activity

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12 December 2020

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

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12 December 2020

Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs

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12 December 2020

Transcriptional regulation by the phosphorylation-dependent factor CREB

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12 December 2020

Neural cell adhesion molecules influence second messenger systems

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12 December 2020

Tyrosine kinase inhibitors can differentially inhibit integrin-dependent and CAM-stimulated neurite outgrowth

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12 December 2020

Neurite outgrowth stimulated by neural cell adhesion molecules requires growth-associated protein-43 (GAP-43) function and is associated with GAP-43 phosphorylation in growth cones.

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12 December 2020

Tyrosine phosphorylation of focal adhesion kinase stimulated by hepatocyte growth factor leads to mitogen-activated protein kinase activation

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12 December 2020

Homophilic adhesion mediated by the neural cell adhesion molecule involves multiple immunoglobulin domains

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12 December 2020

Isolation and characterization of detergent-resistant microdomains responsive to NCAM-mediated signaling from growth cones

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12 December 2020

Neural cell adhesion molecule-stimulated neurite outgrowth depends on activation of protein kinase C and the Ras-mitogen-activated protein kinase pathway

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12 December 2020

A MAP kinase-signaling pathway mediates neurite outgrowth on L1 and requires Src-dependent endocytosis.

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12 December 2020

The first immunoglobulin-like neural cell adhesion molecule (NCAM) domain is involved in double-reciprocal interaction with the second immunoglobulin-like NCAM domain and in heparin binding.

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12 December 2020

Cross talk between ERK and PKA is required for Ca2+ stimulation of CREB-dependent transcription and ERK nuclear translocation.

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12 December 2020

Calmodulin kinase II attenuation of gene transcription by preventing cAMP response element-binding protein (CREB) dimerization and binding of the CREB-binding protein

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12 December 2020

Neurite outgrowth of neuroblastoma cells overexpressing alpha and beta isoforms of Ca2+/calmodulin-dependent protein kinase II-effects of protein kinase inhibitors

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12 December 2020

Laminin directs growth cone navigation via two temporally and functionally distinct calcium signals.

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12 December 2020

Overexpression of Ca2+/calmodulin-dependent protein kinase II in Neuro2a and NG108-15 neuroblastoma cell lines promotes neurite outgrowth and growth cone motility.

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12 December 2020

Morphoregulatory activities of NCAM and N-cadherin can be accounted for by G protein-dependent activation of L- and N-type neuronal Ca2+ channels

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12 December 2020

Mutual antagonism of calcium entry by capacitative and arachidonic acid-mediated calcium entry pathways

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12 December 2020

CAMs and FGF cause a local submembrane calcium signal promoting axon outgrowth without a rise in bulk calcium concentration

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12 December 2020

NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus mice

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12 December 2020

Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin

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12 December 2020

A Ca2+/Calmodulin Kinase Inhibitor, KN-62, Inhibits Neurite Outgrowth Stimulated by CAMs and FGF

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12 December 2020

Integration of MAP kinase signal transduction pathways at the serum response element

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12 December 2020

Protein kinase C and lipid signaling for sustained cellular responses

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12 December 2020

Shc and a novel 89-kDa component couple to the Grb2-Sos complex in fibroblast growth factor-2-stimulated cells

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12 December 2020

CAM-FGF receptor interactions: a model for axonal growth

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12 December 2020

N-CAM binding inhibits the proliferation of hippocampal progenitor cells and promotes their differentiation to a neuronal phenotype.

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12 December 2020

The role of phosphatidylinositol 3-kinase in neural cell adhesion molecule-mediated neuronal differentiation and survival

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12 December 2020

Overexpression of epsilon-protein kinase C enhances nerve growth factor-induced phosphorylation of mitogen-activated protein kinases and neurite outgrowth

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12 December 2020

Induction of neurite outgrowth by MAP kinase in PC12 cells

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12 December 2020

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

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12 December 2020

NF-kappaB activity is induced by neural cell adhesion molecule binding to neurons and astrocytes

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12 December 2020

In vivo regulation of axon extension and pathfinding by growth-cone calcium transients

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12 December 2020

Protein kinase C-epsilon is implicated in neurite outgrowth in differentiating human neuroblastoma cells

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12 December 2020

The EGF and FGF receptors mediate neuroglian function to control growth cone decisions during sensory axon guidance in Drosophila.

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12 December 2020

Fibroblast growth factors stimulate protein tyrosine phosphorylation and mitogen-activated protein kinase activity in primary cultures of hippocampal neurons

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12 December 2020

Nerve growth factor induces survival and differentiation through two distinct signaling cascades in PC12 cells.

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12 December 2020

Characterisation of the second messenger pathway underlying neurite outgrowth stimulated by FGF.

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12 December 2020

Calphostin C, a widely used protein kinase C inhibitor, directly and potently blocks L-type Ca channels

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12 December 2020

Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth.

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12 December 2020