(Q28646141)

3 February 2017

title

Structural fingerprints of the Ras-GTPase activating proteins neurofibromin and p120GAP (English)

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3 February 2017

author

Mohammad Reza Ahmadian

1

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Klaus Scheffzek

4

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author name string

Christina Kiel

2

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3 February 2017

Patricia Stege

3

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3 February 2017

language of work or name

English

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publication date

13 June 2003

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Journal of Molecular Biology

3 February 2017

published in

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3 February 2017

volume

329

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3 February 2017

issue

4

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3 February 2017

page(s)

699–710

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The GTPase superfamily: a conserved switch for diverse cell functions

3 February 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The guanine nucleotide-binding switch in three dimensions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Biological and biochemical properties of human rasH genes mutated at codon 61.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

GTPase-activating proteins: helping hands to complement an active site

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

NF1 tumor suppressor gene function: narrowing the GAP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The neurofibromatosis type 1 gene encodes a protein related to GAP

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Molecular cloning of two types of GAP complementary DNA from human placenta

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Cloning of bovine GAP and its interaction with oncogenic ras p21.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Ras-GAP SH3 domain binding protein (G3BP) is a modulator of USP10, a novel human ubiquitin specific protease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Investigating the role played by protein-lipid and protein-protein interactions in the membrane association of the p120GAP CaLB domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Vascular system defects and neuronal apoptosis in mice lacking ras GTPase-activating protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The NF1 gene in myelopoiesis and childhood myelodysplastic syndromes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

A conserved alternative splice in the von Recklinghausen neurofibromatosis (NF1) gene produces two neurofibromin isoforms, both of which have GTPase-activating protein activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

N-terminal sequences contained in the Src homology 2 and 3 domains of p120 GTPase-activating protein are required for full catalytic activity toward Ras.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The Ras/p120 GTPase-activating protein (GAP) interaction is regulated by the p120 GAP pleckstrin homology domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Kinetics of inorganic phosphate release during the interaction of p21ras with the GTPase-activating proteins, p120-GAP and neurofibromin.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Aluminum fluoride associates with the small guanine nucleotide binding proteins.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Signaling mechanistics: aluminum fluoride for molecule of the year

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The arginine finger of RasGAP helps Gln-61 align the nucleophilic water in GAP-stimulated hydrolysis of GTP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Crystal structure of the GTPase-activating domain of human p120GAP and implications for the interaction with Ras

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Structural analysis of the GAP-related domain from neurofibromin and its implications

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

p120 Ras GTPase-activating protein interacts with Ras-GTP through specific conserved residues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

The arginine finger loop of yeast and human GAP is a determinant for the specificity toward Ras GTPase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Selective disactivation of neurofibromin GAP activity in neurofibromatosis type 1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Mechanism of GTP hydrolysis by p21N-ras catalyzed by GAP: studies with a fluorescent GTP analogue

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Somatic mutations in the neurofibromatosis 1 gene in human tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Mutational and functional analysis of the neurofibromatosis type 1 (NF1) gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Identification of neurofibromin mutants that exhibit allele specificity or increased Ras affinity resulting in suppression of activated ras alleles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Suppression of oncogenic Ras by mutant neurofibromatosis type 1 genes with single amino acid substitutions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Targeted disruption of the neurofibromatosis type-1 gene leads to developmental abnormalities in heart and various neural crest-derived tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Tumour predisposition in mice heterozygous for a targeted mutation in Nf1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

A putative Ras GTPase activating protein acts as a negative regulator of signaling by the Sevenless receptor tyrosine kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Rescue of a Drosophila NF1 mutant phenotype by protein kinase A.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Neurofibromin GTPase-activating protein-related domains restore normal growth in Nf1-/- cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

RanGAP mediates GTP hydrolysis without an arginine finger

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Rap-specific GTPase activating protein follows an alternative mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Molecular switch for signal transduction: structural differences between active and inactive forms of protooncogenic ras proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Solution structure and dynamics of ras p21.GDP determined by heteronuclear three- and four-dimensional NMR spectroscopy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Structural differences in the minimal catalytic domains of the GTPase-activating proteins p120GAP and neurofibromin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Guanosine triphosphatase stimulation of oncogenic Ras mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0022-2836%2803%2900514-X

10.1016/S0022-2836(03)00514-X

7 January 2021

Identifiers

DOI

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017