(Q43867605)

27 November 2017

Rap-specific GTPase activating protein follows an alternative mechanism (English)

1 reference

27 November 2017

7

Alfred Wittinghofer

1 reference

27 November 2017

2

Oliver Daumke

1 reference

27 November 2017

Thilo Brinkmann

1

1 reference

27 November 2017

Ulrike Herbrand

3

1 reference

27 November 2017

Dorothee Kühlmann

4

1 reference

27 November 2017

Patricia Stege

5

1 reference

27 November 2017

Mohammad Reza Ahmadian

6

1 reference

27 November 2017

language of work or name

English

0 references

publication date

25 January 2002

1 reference

Journal of Biological Chemistry

27 November 2017

1 reference

27 November 2017

277

1 reference

27 November 2017

12525-12531

1 reference

27 November 2017

15

1 reference

Rap1 signalling: adhering to new models

27 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Extracellular signal-regulated activation of Rap1 fails to interfere in Ras effector signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Mitogenic and oncogenic properties of the small G protein Rap1b

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Microinjection of smg/rap1/Krev-1 p21 into Swiss 3T3 Cells Induces DNA Synthesis and Morphological Changes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The small GTPase, Rap1, mediates CD31-induced integrin adhesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Rap1 is a potent activation signal for leukocyte function-associated antigen 1 distinct from protein kinase C and phosphatidylinositol-3-OH kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The GTPase Rap1 controls functional activation of macrophage integrin alphaMbeta2 by LPS and other inflammatory mediators

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

C3G, a guanine nucleotide-releasing protein expressed ubiquitously, binds to the Src homology 3 domains of CRK and GRB2/ASH proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Identification of Rap1 as a target for the Crk SH3 domain-binding guanine nucleotide-releasing factor C3G

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

PDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

A Rap guanine nucleotide exchange factor enriched highly in the basal ganglia

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Cloning and characterization of Ras-GRF2, a novel guanine nucleotide exchange factor for Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Proteins regulating Ras and its relatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The structural basis of the activation of Ras by Sos

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Purification of a plasma membrane-associated GTPase-activating protein specific for rap1/Krev-1 from HL60 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Molecular cloning of a GTPase activating protein specific for the Krev-1 protein p21rap1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i)

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Modulation of rap activity by direct interaction of Galpha(o) with Rap1 GTPase-activating protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Functional interaction between Galpha(z) and Rap1GAP suggests a novel form of cellular cross-talk

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The GoLoco motif: a Galphai/o binding motif and potential guanine-nucleotide exchange factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Human SPA-1 gene product selectively expressed in lymphoid tissues is a specific GTPase-activating protein for Rap1 and Rap2. Segregate expression profiles from a rap1GAP gene product

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The E6 oncoproteins of high-risk papillomaviruses bind to a novel putative GAP protein, E6TP1, and target it for degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Identification of tuberin, the tuberous sclerosis-2 product. Tuberin possesses specific Rap1GAP activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Identification of a specific Ins(1,3,4,5)P4-binding protein as a member of the GAP1 family

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structure at 1.65 A of RhoA and its GTPase-activating protein in complex with a transition-state analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

GTPase-activating proteins: helping hands to complement an active site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Identification of the catalytic domains and their functionally critical arginine residues of two yeast GTPase-activating proteins specific for Ypt/Rab transport GTPases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Crystal structure of the GAP domain of Gyp1p: first insights into interaction with Ypt/Rab proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Rac downregulates Rho activity: reciprocal balance between both GTPases determines cellular morphology and migratory behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Short-term, high-efficiency expression of transfected DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Biochemical characterization of baculovirus-expressed rap1A/Krev-1 and its regulation by GTPase-activating proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Site-directed mutagenesis, fluorescence, and two-dimensional NMR studies on microenvironments of effector region aromatic residues of human c-Ha-Ras protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Crystal structure of the ARF-GAP domain and ankyrin repeats of PYK2-associated protein beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structure of ADP x AIF4(-)-stabilized nitrogenase complex and its implications for signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Ras/Rap effector specificity determined by charge reversal

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Crystal structures of the small G protein Rap2A in complex with its substrate GTP, with GDP and with GTPgammaS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Interactions between Ras proteins and their effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The guanine nucleotide-binding switch in three dimensions

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

21 January 2018

Ras and its effectors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structural basis for the interaction of Ras with RalGDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Rapid Ca2+-mediated activation of Rap1 in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The Crystal Structure of rna1p

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Kinetic analysis by fluorescence of the interaction between Ras and the catalytic domain of the guanine nucleotide exchange factor Cdc25Mm

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Discriminatory residues in Ras and Rap for guanine nucleotide exchange factor recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

The conserved arginine in rho-GTPase-activating protein is essential for efficient catalysis but not for complex formation with Rho.GDP and aluminum fluoride

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Stereochemistry of the elongation factor Tu . GTP complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Is there a rate-limiting step before GTP cleavage by H-ras p21?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Individual Rate Constants for the Interaction of Ras Proteins with GTPase-Activating Proteins Determined by Fluorescence Spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structural and functional analysis of the ARF1-ARFGAP complex reveals a role for coatomer in GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

Structural and biochemical analysis of Ras-effector signaling via RalGDS

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109176200

21 January 2018

Identifiers

DOI

10.1074/JBC.M109176200

1 reference

27 November 2017

1 reference