(Q28661646)

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Personalized medicine in human space flight: using Omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance

scientific article (publication date: 2013)

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scholarly article

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Personalized medicine in human space flight: using Omics based analyses to develop individualized countermeasures that enhance astronaut safety and performance (English)

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clinical chemistry

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1 reference

based on heuristic

inferred from title

personalized medicine

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based on heuristic

inferred from title

author name string

Michael A Schmidt

1

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Thomas J Goodwin

2

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language of work or name

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publication date

2013

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9

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6

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1134-1156

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copyright license

Creative Commons Attribution 2.0 Generic

27 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Optic disc edema, globe flattening, choroidal folds, and hyperopic shifts observed in astronauts after long-duration space flight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

17 March 2017

Bench-to-bedside review: oxygen as a drug

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

17 March 2017

Codeine intoxication associated with ultrarapid CYP2D6 metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

17 March 2017

High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased K(m)): relevance to genetic disease and polymorphisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

17 March 2017

Radiation Will Make Astronauts' Trip to Mars Even Riskier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

7 April 2017

Measurements of energetic particle radiation in transit to Mars on the Mars Science Laboratory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Radiation mitigating properties of the lignan component in flaxseed

1 reference

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3 June 2018

Does a role for selenium in DNA damage repair explain apparent controversies in its use in chemoprevention?

1 reference

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3 June 2018

X-aptamers: a bead-based selection method for random incorporation of druglike moieties onto next-generation aptamers for enhanced binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Visual stability of laser vision correction in an astronaut on a Soyuz mission to the International Space Station

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Homocysteine level and risk of fracture: A meta-analysis and systematic review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Vision changes after spaceflight are related to alterations in folate- and vitamin B-12-dependent one-carbon metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Brain structure in healthy adults is related to serum transferrin and the H63D polymorphism in the HFE gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

PH2O and simulated hypobaric hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Niacin requirements for genomic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Folate (vitamin B9) and vitamin B12 and their function in the maintenance of nuclear and mitochondrial genome integrity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Polarized distribution of heme transporters in retinal pigment epithelium and their regulation in the iron-overload disease hemochromatosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Long space missions, gene therapy, and the vital role of magnesium: a three-pronged plan for the next 50 years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

The role of N-methyl-D-aspartate receptor activation in homocysteine-induced death of retinal ganglion cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

HFE gene variants affect iron in the brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

In vivo space radiation-induced non-targeted responses: late effects on molecular signaling in mitochondria.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Detection of 100% oxygen induced changes in retina using magnetic resonance imaging: a human study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Aptamers as affinity reagents in an integrated electrophoretic lab-on-a-chip platform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Role of nicotinamide in DNA damage, mutagenesis, and DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Prolonged space flight-induced alterations in the structure and function of human skeletal muscle fibres.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Correlation between folate and vitamin B₁₂ and markers of DNA stability in healthy men: preliminary results

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Dietary reference values of individual micronutrients and nutriomes for genome damage prevention: current status and a road map to the future

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Omics-based medicine and systems pathology. A new perspective for personalized and predictive medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Pharmacogenetics of phase I and phase II drug metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Does oxidative stress modulate left ventricular diastolic function in asymptomatic subjects with hereditary hemochromatosis?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Reduction in proximal femoral strength due to long-duration spaceflight.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Synergistic effects of the MTHFR C677T polymorphism and hypertension on spatial navigation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Critique of the equivalent air altitude model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Dietary magnesium and DNA repair capacity as risk factors for lung cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Low dietary riboflavin but not folate predicts increased fracture risk in postmenopausal women homozygous for the MTHFR 677 T allele.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Choline deficiency increases lymphocyte apoptosis and DNA damage in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Adverse drug reactions result in 250,000 UK admissions a year

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Intracellular signaling mechanisms of acetaminophen-induced liver cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Folic acid deficiency increases chromosomal instability, chromosome 21 aneuploidy and sensitivity to radiation-induced micronuclei

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Hemochromatosis and iron-overload screening in a racially diverse population.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

The nutritional status of astronauts is altered after long-term space flight aboard the International Space Station

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Bone markers, calcium metabolism, and calcium kinetics during extended-duration space flight on the mir space station.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Zinc deficiency, DNA damage and cancer risk

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Developmental regulation of dUTPase in Drosophila melanogaster

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Structure and function of nucleases in DNA repair: shape, grip and blade of the DNA scissors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Red blood cell and iron metabolism during space flight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Calcium and bone metabolism during space flight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Magnesium-DNA interactions and the possible relation of magnesium to carcinogenesis. Irradiation and free radicals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Space radiation and cataracts in astronauts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Nutritional status assessment in semiclosed environments: ground-based and space flight studies in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Role of magnesium in genomic stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

DNA damage from micronutrient deficiencies is likely to be a major cause of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Micronuclei in lymphocytes and exfoliated buccal cells of postmenopausal women with dietary changes in folate

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Folate, vitamin B12, homocysteine status and DNA damage in young Australian adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Folate deficiency causes uracil misincorporation into human DNA and chromosome breakage: implications for cancer and neuronal damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Retinal changes in rats flown on Cosmos 936: A cosmic ray experiment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Binding of triple helix forming oligonucleotides to sites in gene promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

3 June 2018

Urinary excretion of biomarkers of oxidatively damaged DNA and RNA in hereditary hemochromatosis

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Homocysteine and vitamin B12 status relate to bone turnover markers, broadband ultrasound attenuation, and fractures in healthy elderly people.

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Micronuclei, nucleoplasmic bridges and nuclear buds induced in folic acid deficient human lymphocytes-evidence for breakage-fusion-bridge cycles in the cytokinesis-block micronucleus assay

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Clinical expression of haemochromatosis in Irish C282Y homozygotes identified through family screening.

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

The effect of age on the non-haemin iron in the human brain.

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Uracil misincorporation into DNA of leukocytes of young women with positive folate balance depends on plasma vitamin B12 concentrations and methylenetetrahydrofolate reductase polymorphisms. A pilot study

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Thrombophilic factors in idiopathic intracranial hypertension: a report of 51 patients and a meta-analysis

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

The ALTEA/ALTEINO projects: studying functional effects of microgravity and cosmic radiation.

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Benefits for bone from resistance exercise and nutrition in long-duration spaceflight: Evidence from biochemistry and densitometry

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Iron status and its relations with oxidative damage and bone loss during long-duration space flight on the International Space Station

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Nutritional status assessment before, during, and after long-duration head-down bed rest

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Stimulation of osteoclast activity by low B-vitamin concentrations

1 reference

https://api.crossref.org/works/10.1007%2FS11306-013-0556-3

21 January 2018

Human spaceflight health systems for the Constellation Project.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

27 November 2018

Relation between homocysteine and biochemical bone turnover markers and bone mineral density in peri- and post-menopausal women

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

27 November 2018

Diet as a factor in behavioral radiation protection following exposure to heavy particles.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

27 November 2018

Folate deficiency and ionizing radiation cause DNA breaks in primary human lymphocytes: a comparison

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3825629

27 November 2018

Oxidative stress is associated with genetic polymorphisms in one-carbon metabolism in coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased urinary excretion of 8-iso-prostaglandin F2alpha in patients with HFE-related hemochromatosis: a case-control study

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Riboflavin offers a targeted strategy for managing hypertension in patients with the MTHFR 677TT genotype: a 4-y follow-up

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regarding "diurnal pattern of intraocular pressure is affected by microgravity when measured in space with the pressure phosphene tonometer"

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired functioning of thermolabile methylenetetrahydrofolate reductase is dependent on riboflavin status: implications for riboflavin requirements

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ionizing radiation-induced bioeffects in space and strategies to reduce cellular injury and carcinogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dietary magnesium depletion affects metabolic responses during submaximal exercise in postmenopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Large-scale population-based metabolic phenotyping of thirteen genetic polymorphisms related to one-carbon metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of folic acid deficiency and MTHFR C677T polymorphism on spontaneous and radiation-induced micronuclei in human lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cosmic ray effects on the eyes of rats flown on Cosmos No. 782, experimental K-007

1 reference

https://pubmed.ncbi.nlm.nih.gov/24273472

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11306-013-0556-3

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

0 references

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