(Q29036869)

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Development of Hematopoietic Stem Cell Based Gene Therapy for HIV-1 Infection: Considerations for Proof of Concept Studies and Translation to Standard Medical Practice

scientific article (publication date: 22 November 2013)

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Development of Hematopoietic Stem Cell Based Gene Therapy for HIV-1 Infection: Considerations for Proof of Concept Studies and Translation to Standard Medical Practice (English)

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

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David L. Digiusto

1

object named as

David DiGiusto

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

author name string

Rodica Stan

2

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

Amrita Krishnan

3

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

Haitang Li

4

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

John Rossi

5

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

John Zaia

6

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

publication date

22 November 2013

1 reference

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https://doi.org/10.3390%2FV5112898

27 March 2017

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

5

1 reference

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

11

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DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

2898-2919

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DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

copyright license

Creative Commons Attribution 4.0 International

22 November 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Engineering HIV-1-resistant T-cells from short-hairpin RNA-expressing hematopoietic stem/progenitor cells in humanized BLT mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

6 April 2017

Redefining the viral reservoirs that prevent HIV-1 eradication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

6 April 2017

Incomplete immune recovery in HIV infection: mechanisms, relevance for clinical care, and possible solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

6 April 2017

Hematopoietic-stem-cell-based gene therapy for HIV disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

6 April 2017

Evidence for the cure of HIV infection by CCR5Δ32/Δ32 stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

6 April 2017

Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

6 April 2017

Long-term control of HIV by CCR5 Delta32/Delta32 stem-cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

7 April 2017

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

7 April 2017

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

7 April 2017

Recovery of replication-competent HIV despite prolonged suppression of plasma viremia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

7 April 2017

Stem cell mobilization in HIV seropositive patients with lymphoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

HIV-1 infection of hematopoietic progenitor cells in vivo in humanized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Positive selection of mC46-expressing CD4+ T cells and maintenance of virus specific immunity in a primate AIDS model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Challenges in detecting HIV persistence during potentially curative interventions: a study of the Berlin patient

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

CD133+ hematopoietic progenitor cells harbor HIV genomes in a subset of optimally treated people with long-term viral suppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Long-term reduction in peripheral blood HIV type 1 reservoirs following reduced-intensity conditioning allogeneic stem cell transplantation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Economic savings versus health losses: the cost-effectiveness of generic antiretroviral therapy in the United States

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Using the BLT humanized mouse as a stem cell based gene therapy tumor model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Inhibitory effect of HIV-specific neutralizing IgA on mucosal transmission of HIV in humanized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Creating genetic resistance to HIV.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Gene therapy for adenosine deaminase-deficient severe combined immune deficiency: clinical comparison of retroviral vectors and treatment plans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Renal toxicity associated with antiretroviral therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Endogenous MCM7 microRNA cluster as a novel platform to multiplex small interfering and nucleolar RNAs for combinational HIV-1 gene therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Liver toxicity of antiretroviral drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

HAART to heart: highly active antiretroviral therapy and the risk of cardiovascular disease in HIV-infected or exposed children and adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Latent HIV-1 infection occurs in multiple subsets of hematopoietic progenitor cells and is reversed by NF-κB activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Economics of hematopoietic cell transplantation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Fat redistribution syndromes associated with HIV-1 infection and combination antiretroviral therapy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

In vivo selection of autologous MGMT gene-modified cells following reduced-intensity conditioning with BCNU and temozolomide in the dog model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

HIV medications: an update and review of metabolic complications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Newer drugs and earlier treatment: impact on lifetime cost of care for HIV-infected adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Retroviral gene therapy for X-linked chronic granulomatous disease: results from phase I/II trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Plerixafor: a review of its use in stem-cell mobilization in patients with lymphoma or multiple myeloma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Potential strategies for an HIV infection cure

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Allogeneic haematopoietic stem cell transplantation in patients with human immunodeficiency virus: the experiences of more than 25 years

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Long-term mortality in HIV patients virally suppressed for more than three years with incomplete CD4 recovery: a cohort study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

RNA-based gene therapy for HIV with lentiviral vector-modified CD34(+) cells in patients undergoing transplantation for AIDS-related lymphoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Immune exhaustion occurs concomitantly with immune activation and decrease in regulatory T cells in viremic chronically HIV-1-infected patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Inhibition of in vivo HIV infection in humanized mice by gene therapy of human hematopoietic stem cells with a lentiviral vector encoding a broadly neutralizing anti-HIV antibody

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Retrovirus gene therapy for X-linked chronic granulomatous disease can achieve stable long-term correction of oxidase activity in peripheral blood neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Phase 2 gene therapy trial of an anti-HIV ribozyme in autologous CD34+ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Impaired in-vitro growth of megakaryocytic colonies derived from CD34 cells of HIV-1-infected patients with active viral replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Optimization and functional effects of stable short hairpin RNA expression in primary human lymphocytes via lentiviral vectors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Correction of X-linked chronic granulomatous disease by gene therapy, augmented by insertional activation of MDS1-EVI1, PRDM16 or SETBP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Lentivirus-mediated expression of mutant MGMTP140K protects human CD34+ cells against the combined toxicity of O6-benzylguanine and 1,3-bis(2-chloroethyl)-nitrosourea or temozolomide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Early and persistent bone marrow hematopoiesis defect in simian/human immunodeficiency virus-infected macaques despite efficient reduction of viremia by highly active antiretroviral therapy during primary infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Predictors of therapy-related leukemia and myelodysplasia following autologous transplantation for lymphoma: an assessment of risk factors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

3 June 2018

Selective survival of peripheral blood lymphocytes in children with HIV-1 following delivery of an anti-HIV gene to bone marrow CD34(+) cells

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Anti-human immunodeficiency virus hematopoietic progenitor cell-delivered ribozyme in a phase I study: myeloid and lymphoid reconstitution in human immunodeficiency virus type-1-infected patients

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Long-term inhibition of HIV-1 infection in primary hematopoietic cells by lentiviral vector delivery of a triple combination of anti-HIV shRNA, anti-CCR5 ribozyme, and a nucleolar-localizing TAR decoy

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

A genome-wide analysis of lentivector integration sites using targeted sequence capture and next generation sequencing technology.

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Characterization of the P140K, PVP(138-140)MLK, and G156A O6-methylguanine-DNA methyltransferase mutants: implications for drug resistance gene therapy

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Hematoprotection and enrichment of transduced cells in vivo after gene transfer of MGMT(P140K) into hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Polyclonal chemoprotection against temozolomide in a large-animal model of drug resistance gene therapy

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Development of a framework for enhancing the transparency, reproducibility and communication of the benefit-risk balance of medicines.

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Correlates of lending needles/syringes among HIV-seropositive injection drug users

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Long-term clinical outcome of human immunodeficiency virus-infected patients with discordant immunologic and virologic responses to a protease inhibitor-containing regimen

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Altered clonogenic capability and stromal cell function characterize bone marrow of HIV-infected subjects with low CD4+ T cell counts despite viral suppression during HAART.

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Abnormalities of erythropoiesis during HIV-1 disease: a longitudinal analysis.

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

HIV-infected patients

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Durable remissions with autologous stem cell transplantation for high-risk HIV-associated lymphomas

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Reduced mobilization of CD34+ stem cells in advanced human immunodeficiency virus type 1 disease

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Gene therapy for immunodeficiency due to adenosine deaminase deficiency.

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

Comprehensive genomic access to vector integration in clinical gene therapy

1 reference

https://api.crossref.org/works/10.3390%2FV5112898

21 January 2018

High incidence of zidovudine induced anaemia in HIV infected patients in eastern India.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

26 November 2018

A clinical trial of retroviral-mediated transfer of a rev-responsive element decoy gene into CD34(+) cells from the bone marrow of human immunodeficiency virus-1-infected children.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3856421

26 November 2018

HIV-infected adults with a CD4 cell count greater than 500 cells/mm3 on long-term combination antiretroviral therapy reach same mortality rates as the general population

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Towards a cure for HIV: the identification and characterization of HIV reservoirs in optimally treated people

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DNA sequencing by hybridization with arrays of samples or probes

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-myeloablative stem cell transplantation in patients with relapsed acute lymphoblastic leukemia: results of a multicenter study

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV-Induced Abnormalities in Myelopoiesis and their Recovery Following Antiretroviral Therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/24284880

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.3390/V5112898

2 references

DOI.org query endpoint

https://doi.org/10.3390%2FV5112898

27 March 2017

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

ResearchGate publication ID

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