(Q29615385)

title

Cisplatin: mode of cytotoxic action and molecular basis of resistance (English)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

30 April 2017

0 references

1 reference

antineoplastic resistance

1 reference

14576837

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576837

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206933

24 March 2024

author name string

Zahid H. Siddik

1

1 reference

14576837

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576837

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

24 March 2024

language of work or name

1 reference

30 April 2017

publication date

20 October 2003

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

full work available at URL

30 April 2017

https://www.nature.com/articles/1206933.pdf

file format

Portable Document Format

online access status

open access

1 reference

14576837

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A14576837

https://www.nature.com/articles/1206933.pdf

24 March 2024

file format

Portable Document Format

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206933

https://www.nature.com/articles/1206933

24 March 2024

1 reference

https://api.crossref.org/works/10.1038/SJ.ONC.1206933

24 March 2024

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

30 April 2017

volume

22

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

30 April 2017

issue

47

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

30 April 2017

page(s)

7265-79

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

p53-Mdm2--the affair that never ends

30 April 2017

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Characterization of a DNA damage-recognition protein from mammalian cells that binds specifically to intrastrand d(GpG) and d(ApG) DNA adducts of the anticancer drug cisplatin

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Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

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Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct

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Identification of p53 genetic suppressor elements which confer resistance to cisplatin

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Cellular accumulation of the anticancer agent cisplatin: a review

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Clinical perspectives on platinum resistance

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High resistance to cisplatin in human ovarian cancer cell lines is associated with marked increase of glutathione synthesis

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7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

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Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin

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Effect of the antitumor drug cis-diamminedichloroplatinum(II) and related platinum complexes on eukaryotic DNA replication

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Biological properties of ten human ovarian carcinoma cell lines: calibration in vitro against four platinum complexes

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7 January 2021

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

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p53 mutations in human cancers

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7 January 2021

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7 January 2021

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7 January 2021

The relationships between glutathione, glutathione-S-transferase and cytotoxicity of platinum drugs and melphalan in eight human ovarian carcinoma cell lines

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7 January 2021

Synergistic enhancement of resistance to cisplatin in human bladder cancer cells by overexpression of mutant-type p53 and Bcl-2.

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7 January 2021

p53 and ATM: cell cycle, cell death, and cancer.

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7 January 2021

Metallothionein levels in ovarian tumours before and after chemotherapy

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7 January 2021

Regulation of p53: intricate loops and delicate balances

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7 January 2021

Effect of extracellular signal-regulated kinase on p53 accumulation in response to cisplatin

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7 January 2021

Sequence-specific transcriptional activation is essential for growth suppression by p53.

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7 January 2021

Mitogen-activated protein kinase pathways

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7 January 2021

Mechanisms of DNA excision repair

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7 January 2021

Regulation of p73 by c-Abl through the p38 MAP kinase pathway.

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7 January 2021

Prognostic value of p53 nuclear overexpression in patients with invasive bladder cancer treated with neoadjuvant MVAC

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7 January 2021

Specific in vitro binding of p53 to the promoter region of the human mismatch repair gene hMSH2

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7 January 2021

Anticancer drug targets: cell cycle and checkpoint control.

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7 January 2021

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7 January 2021

Premature p34cdc2 activation required for apoptosis.

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7 January 2021

DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2

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7 January 2021

Role of p53 in the ability of 1,2-diaminocyclohexane-diacetato-dichloro-Pt(IV) to circumvent cisplatin resistance

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

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7 January 2021

Enhanced chemoresistance by elevation of p185neu levels in HER-2/neu-transfected human lung cancer cells.

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7 January 2021

Value of P-glycoprotein, glutathione S-transferase pi, c-erbB-2, and p53 as prognostic factors in ovarian carcinomas

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7 January 2021

Requirement for ERK activation in cisplatin-induced apoptosis

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7 January 2021

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7 January 2021

MutS preferentially recognizes cisplatin- over oxaliplatin-modified DNA.

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7 January 2021

Requirement of ATM in UVA-induced signaling and apoptosis.

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7 January 2021

Metallothionein-mediated cisplatin resistance in human ovarian carcinoma cells.

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Post-translational modifications and activation of p53 by genotoxic stresses

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Genomic dissection reveals locus response to stress for mammalian acetylcholinesterase.

24 March 2024

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The antitumour activity of alkylating agents is not correlated with the levels of glutathione, glutathione transferase and O6-alkylguanine-DNA-alkyltransferase of human tumour xenografts

24 March 2024

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24 March 2024

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p53 interacts with the DNA mismatch repair system to modulate the cytotoxicity and mutagenicity of hydrogen peroxide

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Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate

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The MEK1 inhibitor PD98059 sensitizes C8161 melanoma cells to cisplatin-induced apoptosis

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Expression of the p53 tumour suppressor gene as a prognostic marker in platinum-treated patients with ovarian cancer

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The PTEN, Mdm2, p53 tumor suppressor-oncoprotein network

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The mismatch-repair protein hMSH2 binds selectively to DNA adducts of the anticancer drug cisplatin

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

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Copper-transporting P-type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP.

24 March 2024

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Loss of p73 induction in a cisplatin-resistant bladder cancer cell line

24 March 2024

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cis-Diamminedichloroplatinum(II)-induced cell death through apoptosis in sensitive and resistant human ovarian carcinoma cell lines

24 March 2024

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Ovarian cancer: new clinical approaches

24 March 2024

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Chemotherapy for advanced epithelial ovarian cancer

24 March 2024

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High-Dose Cisplatin in Hypertonic Saline

24 March 2024

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Reversal of cisplatin resistance in human ovarian cancer cell lines by a c-jun antisense oligodeoxynucleotide (ISIS 10582): evidence for the role of transcription factor overexpression in determining resistant phenotype

24 March 2024

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Binding of the antitumor drug cis-diamminedichloroplatinum(II) (cisplatin) to DNA.

24 March 2024

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Cisplatin (cis-diamminedichloroplatinum II)

24 March 2024

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Induction of apoptosis by cisplatin and its effect on cell cycle-related proteins and cell cycle changes in hepatoma cells.

24 March 2024

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Platinum-DNA adduct, nucleotide excision repair and platinum based anti-cancer chemotherapy.

24 March 2024

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Metallothionein gene expression and resistance to cisplatin in human ovarian cancer

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New therapies for ovarian cancer

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Mechanisms of p53-dependent apoptosis

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Alteration in p53 pathway and defect in apoptosis contribute independently to cisplatin-resistance

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186

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202

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204

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214

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215

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217

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Identifiers

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1035533524

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=14576837

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017