(Q30002303)

English

Identification of Novel Type 1 Diabetes Candidate Genes by Integrating Genome-Wide Association Data, Protein-Protein Interactions, and Human Pancreatic Islet Gene Expression

scientific article (publication date: 16 February 2012)

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scholarly article

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22344559%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

Identification of novel type 1 diabetes candidate genes by integrating genome-wide association data, protein-protein interactions, and human pancreatic islet gene expression (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22344559%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

genome-wide association study

0 references

type-1 diabetes

0 references

protein-protein interaction

1 reference

based on heuristic

inferred from title

Caroline Brorsson

2

1 reference

Europe PubMed Central

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23 January 2020

3

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23 January 2020

Claus Heiner Bang-Berthelsen

6

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23 January 2020

Lars Juhl Jensen

8

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23 January 2020

Joachim Størling

9

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23 January 2020

Flemming Pociot

10

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23 January 2020

author name string

Regine Bergholdt

1

1 reference

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23 January 2020

Lukas A Berchtold

4

1 reference

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23 January 2020

Tina Fløyel

5

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23 January 2020

Klaus Stensgaard Frederiksen

7

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23 January 2020

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publication date

16 February 2012

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23 January 2020

2 references

Europe PubMed Central

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23 January 2020

61

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23 January 2020

4

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23 January 2020

954-962

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23 January 2020

copyright license

Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

27 August 2021

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April 2022 Public Data File from Crossref

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0 references

Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

Common variants at TRAF3IP2 are associated with susceptibility to psoriatic arthritis and psoriasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

CXCR7 functions as a scavenger for CXCL12 and CXCL11

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

STRING 8--a global view on proteins and their functional interactions in 630 organisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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Network-based classification of breast cancer metastasis

1 reference

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22 May 2017

Network modeling links breast cancer susceptibility and centrosome dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

Global landscape of protein complexes in the yeast Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

A network-based analysis of systemic inflammation in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

The KEGG resource for deciphering the genome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

An efficient algorithm for large-scale detection of protein families

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

Gene ontology: tool for the unification of biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

The function of GRB2 in linking the insulin receptor to Ras signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

22 May 2017

Synergistic reversal of type 1 diabetes in NOD mice with anti-CD3 and interleukin-1 blockade: evidence of improved immune regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Genetics of type 1 diabetes: what's next?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Integrating pathway analysis and genetics of gene expression for genome-wide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

The type 1 diabetes - HLA susceptibility interactome--identification of HLA genotype-specific disease genes for type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

The genetic interpretation of area under the ROC curve in genomic profiling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

An integrative -omics approach to identify functional sub-networks in human colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Expression profiling of human genetic and protein interaction networks in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Prediction and interaction in complex disease genetics: experience in type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Inhibition of Th17 cells regulates autoimmune diabetes in NOD mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Pathway and network-based analysis of genome-wide association studies in multiple sclerosis

1 reference

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3 June 2018

Understanding type 1 diabetes genetics - approaches for identification of susceptibility genes in multi-factorial diseases.

1 reference

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3 June 2018

Cytokines and beta-cell biology: from concept to clinical translation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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FatiGO +: a functional profiling tool for genomic data. Integration of functional annotation, regulatory motifs and interaction data with microarray experiments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

3 June 2018

Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets

1 reference

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Circuitry of nuclear factor kappaB signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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On the pathogenesis of IDDM.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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1 reference

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CXCL10 impairs beta cell function and viability in diabetes through TLR4 signaling.

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Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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CD83 expression influences CD4+ T cell development in the thymus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3314366

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Understanding type 1 diabetes through genetics: advances and prospects

1 reference

https://pubmed.ncbi.nlm.nih.gov/22344559

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inferred from PubMed ID database lookup

Insulin regulation of beta-cell function involves a feedback loop on SERCA gene expression, Ca(2+) homeostasis, and insulin expression and secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/22344559

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based on heuristic

inferred from PubMed ID database lookup

Systemic administration of IL-18 promotes diabetes development in young nonobese diabetic mice

1 reference

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inferred from PubMed ID database lookup

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22344559

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inferred from PubMed ID database lookup

Generalized multi-organ autoimmunity in CCR7-deficient mice

1 reference

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inferred from PubMed ID database lookup

Genomewide association studies--illuminating biologic pathways

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB11-1263

2 references

Consolidated OpenCitations Corpus – April 2017

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23 January 2020

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Consolidated OpenCitations Corpus – April 2017

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2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22344559%20AND%20SRC:MED&resulttype=core&format=json

23 January 2020

PubMed publication ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

Europe PubMed Central

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23 January 2020

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