(Q30009890)

21 May 2017

title

Dynamin 2 potentiates invasive migration of pancreatic tumor cells through stabilization of the Rac1 GEF Vav1 (English)

1 reference

21 May 2017

5

Daniel D Billadeau

1 reference

21 May 2017

Gina L Razidlo

1

1 reference

21 May 2017

Yu Wang

2

1 reference

21 May 2017

Jing Chen

3

1 reference

21 May 2017

Eugene W Krueger

4

1 reference

21 May 2017

Mark A McNiven

6

1 reference

21 May 2017

language of work or name

English

0 references

publication date

1 March 2013

1 reference

21 May 2017

number of pages

13

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inferred from page(s)

published in

Developmental Cell

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21 May 2017

volume

24

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21 May 2017

issue

6

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21 May 2017

page(s)

573-585

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Chaperone-mediated autophagy: a unique way to enter the lysosome world

21 May 2017

cites work

1 reference

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22 May 2017

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Direct dynamin-actin interactions regulate the actin cytoskeleton

22 May 2017

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A Dyn2-CIN85 complex mediates degradative traffic of the EGFR by regulation of late endosomal budding

22 May 2017

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22 May 2017

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Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected].

22 May 2017

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Chaperone-assisted selective autophagy is essential for muscle maintenance

22 May 2017

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22 May 2017

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22 May 2017

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Ectopic expression of VAV1 reveals an unexpected role in pancreatic cancer tumorigenesis

22 May 2017

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Modulation of Rac localization and function by dynamin

22 May 2017

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Regulated interactions between dynamin and the actin-binding protein cortactin modulate cell shape

22 May 2017

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vav, a novel human oncogene derived from a locus ubiquitously expressed in hematopoietic cells

22 May 2017

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Dynamin 2 mediates PDGFRα-SHP-2-promoted glioblastoma growth and invasion

22 May 2017

1 reference

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Increased expression of the large GTPase dynamin 2 potentiates metastatic migration and invasion of pancreatic ductal carcinoma

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

3 June 2018

Life at the leading edge

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A direct interaction between the large GTPase dynamin-2 and FAK regulates focal adhesion dynamics in response to active Src.

3 June 2018

1 reference

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Nestin is a novel target for suppressing pancreatic cancer cell migration, invasion and metastasis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Eps8 is recruited to lysosomes and subjected to chaperone-mediated autophagy in cancer cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Dynasore, a dynamin inhibitor, suppresses lamellipodia formation and cancer cell invasion by destabilizing actin filaments

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Dynamin2 GTPase and cortactin remodel actin filaments

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

The haematopoietic specific signal transducer Vav1 is aberrantly expressed in lung cancer and plays a role in tumourigenesis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Cell migration is regulated by platelet-derived growth factor receptor endocytosis

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Vav1: a hematopoietic signal transduction molecule involved in human malignancies

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Expression and gene amplification of actinin-4 in invasive ductal carcinoma of the pancreas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Targeted cleavage of signaling proteins by caspase 3 inhibits T cell receptor signaling in anergic T cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Endocytic trafficking of Rac is required for the spatial restriction of signaling in cell migration

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

The ubiquitin-proteasome pathway mediates gelsolin protein downregulation in pancreatic cancer

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Eps8 is increased in pancreatic cancer and required for dynamic actin-based cell protrusions and intercellular cytoskeletal organization

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Dynamin as a mover and pincher during cell migration and invasion

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Activation of Vav/Rho GTPase signaling by CXCL12 controls membrane-type matrix metalloproteinase-dependent melanoma cell invasion

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Microtubule-induced focal adhesion disassembly is mediated by dynamin and focal adhesion kinase

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Vav-family proteins in T-cell signalling

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Regulating actin dynamics at membranes: a focus on dynamin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

The haematopoietic specific signal transducer Vav1 is expressed in a subset of human neuroblastomas

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Dynamin participates in focal extracellular matrix degradation by invasive cells

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

VAV proteins as signal integrators for multi-subunit immune-recognition receptors

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Vav proteins, adaptors and cell signaling.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Dynamin and its role in membrane fission

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Suppressor of cytokine signaling-1 inhibits VAV function through protein degradation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

The dynamin family of mechanoenzymes: pinching in new places

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Tyrosine phosphorylation mediates both activation and downmodulation of the biological activity of Vav

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Cbl-b, a member of the Sli-1/c-Cbl protein family, inhibits Vav-mediated c-Jun N-terminal kinase activation.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Thrombopoietin and thrombin induce tyrosine phosphorylation of Vav in human blood platelets.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

CD44 Regulates Hepatocyte Growth Factor-mediated Vascular Integrity

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Cbl-mediated ubiquitinylation and negative regulation of Vav.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Guanine exchange-dependent and -independent effects of Vav1 on integrin-induced T cell spreading

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3905678

Role of dynamin in the formation of transport vesicles from the trans-Golgi network

26 November 2018

1 reference

12 December 2020

Identification of a novel integrin signaling pathway involving the kinase Syk and the guanine nucleotide exchange factor Vav1

1 reference

12 December 2020

Dynamin 2 regulates T cell activation by controlling actin polymerization at the immunological synapse

1 reference

12 December 2020

Caspase-dependent cleavage and inactivation of the Vav1 proto-oncogene product during apoptosis prevents IL-2 transcription

1 reference

12 December 2020

10.1016/J.DEVCEL.2013.02.010

Identifiers

DOI

1 reference

21 May 2017

0 references

1 reference