(Q30155306)

12 August 2017

Monomer-monomer interactions propagate structural transitions necessary for pore formation by the cholesterol-dependent cytolysins (English)

1 reference

12 August 2017

Michael W Parker

5

0 references

author name string

Eileen M Hotze

1

1 reference

12 August 2017

Elizabeth Wilson-Kubalek

2

1 reference

12 August 2017

Allison J Farrand

3

1 reference

12 August 2017

Lori Bentsen

4

1 reference

12 August 2017

Arthur E Johnson

6

1 reference

12 August 2017

Rodney K Tweten

7

1 reference

12 August 2017

language of work or name

English

0 references

publication date

29 May 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

1 reference

12 August 2017

29

1 reference

12 August 2017

24534-24543

1 reference

Membrane assembly of the cholesterol-dependent cytolysin pore complex

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

The structural basis for membrane binding and pore formation by lymphocyte perforin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Amyloid formation by globular proteins under native conditions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

The MACPF/CDC family of pore-forming toxins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Crystal structure of the MACPF domain of human complement protein C8 alpha in complex with the C8 gamma subunit

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structural elements of the cholesterol-dependent cytolysins that are responsible for their cholesterol-sensitive membrane interactions

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structure of C8alpha-MACPF reveals mechanism of membrane attack in complement immune defense

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

A common fold mediates vertebrate defense and bacterial attack

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Specific protein-membrane contacts are required for prepore and pore assembly by a cholesterol-dependent cytolysin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structures of perfringolysin O suggest a pathway for activation of cholesterol-dependent cytolysins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Protein misfolding, functional amyloid, and human disease

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Molecular basis of listeriolysin O pH dependence

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structural basis of pore formation by the bacterial toxin pneumolysin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Vertical collapse of a cytolysin prepore moves its transmembrane beta-hairpins to the membrane

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Membrane-dependent conformational changes initiate cholesterol-dependent cytolysin oligomerization and intersubunit beta-strand alignment.

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Redefining cholesterol's role in the mechanism of the cholesterol-dependent cytolysins

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structural insights into the membrane-anchoring mechanism of a cholesterol-dependent cytolysin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Monomer-monomer interactions drive the prepore to pore conversion of a beta-barrel-forming cholesterol-dependent cytolysin

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Mechanism of membrane insertion of a multimeric beta-barrel protein: perfringolysin O creates a pore using ordered and coupled conformational changes

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Arresting pore formation of a cholesterol-dependent cytolysin by disulfide trapping synchronizes the insertion of the transmembrane beta-sheet from a prepore intermediate

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

Structure of a cholesterol-binding, thiol-activated cytolysin and a model of its membrane form

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

VMD: visual molecular dynamics

3 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3397878

The Mechanism of Membrane Insertion for a Cholesterol-Dependent Cytolysin

3 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.380139

Identification of a Membrane-Spanning Domain of the Thiol-Activated Pore-Forming ToxinClostridium perfringensPerfringolysin O: An α-Helical to β-Sheet Transition Identified by Fluorescence Spectroscopy†

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.380139

Crystallization and preliminary X-ray analysis of a thiol-activated cytolysin

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.380139

The mechanism of pore assembly for a cholesterol-dependent cytolysin: formation of a large prepore complex precedes the insertion of the transmembrane beta-hairpins

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22645132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interaction of theta-toxin (perfringolysin O), a cholesterol-binding cytolysin, with liposomal membranes: change in the aromatic side chains upon binding and insertion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22645132

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M112.380139

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

22645132

1 reference