(Q30160093)

8 June 2017

The Cbl RING finger C-terminal flank controls epidermal growth factor receptor fate downstream of receptor ubiquitination (English)

1 reference

8 June 2017

protein ubiquitination

1 reference

Gina D Visser

1

1 reference

PubMed ID

16246327

8 June 2017

Nancy L Lill

series ordinal

2

1 reference

PubMed ID

16246327

8 June 2017

language of work or name

English

0 references

publication date

24 October 2005

1 reference

Experimental Cell Research

8 June 2017

1 reference

8 June 2017

311

1 reference

8 June 2017

281-293

1 reference

8 June 2017

2

1 reference

Heterodimerization and functional interaction between EGF receptor family members: a new signaling paradigm with implications for breast cancer research

8 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Dimerization of cell surface receptors in signal transduction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Receptor protein-tyrosine kinases and their signal transduction pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Protein modules and signalling networks

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Eps8, a substrate for the epidermal growth factor receptor kinase, enhances EGF-dependent mitogenic signals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Regulation of epidermal growth factor receptor signaling by endocytosis and intracellular trafficking

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Trafficking of the ErbB receptors and its influence on signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

The RING finger of c-Cbl mediates desensitization of the epidermal growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

The evolutionarily conserved N-terminal region of Cbl is sufficient to enhance down-regulation of the epidermal growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

RING finger mutations that abolish c-Cbl-directed polyubiquitination and downregulation of the EGF receptor are insufficient for cell transformation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Ubiquitin ligase activity and tyrosine phosphorylation underlie suppression of growth factor signaling by c-Cbl/Sli-1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

The tyrosine kinase negative regulator c-Cbl as a RING-type, E2-dependent ubiquitin-protein ligase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Ligand-induced ubiquitination of the epidermal growth factor receptor involves the interaction of the c-Cbl RING finger and UbcH7

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Cbl-CIN85-endophilin complex mediates ligand-induced downregulation of EGF receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

CIN85 participates in Cbl-b-mediated down-regulation of receptor tyrosine kinases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Epidermal growth factor receptor internalization through clathrin-coated pits requires Cbl RING finger and proline-rich domains but not receptor polyubiquitylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

cbl-3: a new mammalian cbl family protein

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Interactions of Drosophila Cbl with epidermal growth factor receptors and role of Cbl in R7 photoreceptor cell development.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Clathrin-independent endocytosis of ubiquitinated cargos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

A novel phosphotyrosine-binding domain in the N-terminal transforming region of Cbl interacts directly and selectively with ZAP-70 in T cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Structure of the amino-terminal domain of Cbl complexed to its binding site on ZAP-70 kinase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

A mutant EGF-receptor defective in ubiquitylation and endocytosis unveils a role for Grb2 in negative signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

c-Cbl-mediated ubiquitinylation is required for epidermal growth factor receptor exit from the early endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Cbl-mediated Ubiquitinylation Is Required for Lysosomal Sorting of Epidermal Growth Factor Receptor but Is Dispensable for Endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Evidence for direct interaction between Sprouty and Cbl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Sprouty fine-tunes EGF signaling through interlinked positive and negative feedback loops

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

hSpry2 is targeted to the ubiquitin-dependent proteasome pathway by c-Cbl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Modulation of signalling by Sprouty: a developing story

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Cbl-dependent ubiquitination is required for progression of EGF receptors into clathrin-coated pits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

The bimodal regulation of epidermal growth factor signaling by human Sprouty proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Characteristics of a human cell line transformed by DNA from human adenovirus type 5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

High-efficiency transformation of mammalian cells by plasmid DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Cbl-mediated negative regulation of the Syk tyrosine kinase. A critical role for Cbl phosphotyrosine-binding domain binding to Syk phosphotyrosine 323

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Tyrosine phosphorylation of Cbl upon epidermal growth factor (EGF) stimulation and its association with EGF receptor and downstream signaling proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Comparative genomic organization of the cbl genes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Tyrosine kinase activity of the EGF receptor is enhanced by the expression of oncogenic 70Z-Cbl

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Cbl-mediated negative regulation of platelet-derived growth factor receptor-dependent cell proliferation. A critical role for Cbl tyrosine kinase-binding domain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Ubiquitination and proteasomal activity is required for transport of the EGF receptor to inner membranes of multivesicular bodies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Ligand-induced lysosomal epidermal growth factor receptor (EGFR) degradation is preceded by proteasome-dependent EGFR de-ubiquitination

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Mammalian sprouty-1 and -2 are membrane-anchored phosphoprotein inhibitors of growth factor signaling in endothelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Grb2 regulates internalization of EGF receptors through clathrin-coated pits

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Growth factor receptor binding protein 2-mediated recruitment of the RING domain of Cbl to the epidermal growth factor receptor is essential and sufficient to support receptor endocytosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Functional independence of the epidermal growth factor receptor from a domain required for ligand-induced internalization and calcium regulation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Effect of tyrosine kinase inhibitors on clathrin-coated pit recruitment and internalization of epidermal growth factor receptor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Hrs and endocytic sorting of ubiquitinated membrane proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

A Di-leucine Signal in the Ubiquitin Moiety

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Monoubiquitin carries a novel internalization signal that is appended to activated receptors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Multiple monoubiquitination of RTKs is sufficient for their endocytosis and degradation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Endocytosis of Receptor Tyrosine Kinases Is Driven by Monoubiquitylation, Not Polyubiquitylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Src-catalyzed phosphorylation of c-Cbl leads to the interdependent ubiquitination of both proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

Structure of a c-Cbl-UbcH7 complex: RING domain function in ubiquitin-protein ligases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YEXCR.2005.09.015

10.1016/J.YEXCR.2005.09.015

7 January 2021

Identifiers

DOI

1 reference

8 June 2017

1 reference

PubMed ID

16246327