(Q30310587)

16 June 2017

1 reference

title

Role of Shc in T-cell development and function (English)

1 reference

16 June 2017

Ulrike Lorenz

2

0 references

Kodi Ravichandran

series ordinal

3

object named as

Kodi S Ravichandran

1 reference

16 June 2017

Li Zhang

1

1 reference

16 June 2017

publication date

1 February 2003

1 reference

16 June 2017

published in

Immunological Reviews

1 reference

16 June 2017

volume

191

1 reference

16 June 2017

page(s)

183-195

1 reference

T cell receptor-mediated signs and signals governing T cell development

16 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

T cell antigen-receptor signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Role of adhesion molecules in activation signaling in T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Signal transduction by lymphocyte antigen receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

New insights into the regulation and functions of Tec family tyrosine kinases in the immune system

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Tec kinases: modulators of lymphocyte signaling and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Signal transduction mediated by the T cell antigen receptor: the role of adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Lymphocytes with a complex: adapter proteins in antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Integration of T cell receptor-dependent signaling pathways by adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

The hematopoietic-specific adaptor protein gads functions in T-cell signaling via interactions with the SLP-76 and LAT adaptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Signaling via Shc family adapter proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Evolution of Shc functions from nematode to human

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Structure and ligand recognition of the phosphotyrosine binding domain of Shc

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

The function of PTB domain proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

SH2 domains, interaction modules and cellular wiring

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

A Drosophila shc Gene Product Is Implicated in Signaling by the DER Receptor Tyrosine Kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Evidence for a role for the phosphotyrosine-binding domain of Shc in interleukin 2 signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Genetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Tyrosine phosphorylation sites at amino acids 239 and 240 of Shc are involved in epidermal growth factor-induced mitogenic signaling that is distinct from Ras/mitogen-activated protein kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Tyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Evidence for a requirement for both phospholipid and phosphotyrosine binding via the Shc phosphotyrosine-binding domain in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Inhibitors of Ras signal transduction as antitumor agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Regulation of T cell development in the thymus

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

T cells: getting a GRP on Ras.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Pleiotropic changes controlled by the pre-T-cell receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Branching out to gain control: how the pre-TCR is linked to multiple functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Molecular determinants of TCR expression and selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Progression of T cell lineage restriction in the earliest subpopulation of murine adult thymus visualized by the expression of lck proximal promoter activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Allelic exclusion of the T cell receptor beta locus requires the SH2 domain-containing leukocyte protein (SLP)-76 adaptor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Essential role of LAT in T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Molecular mechanisms in lymphocyte activation and growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

IL-2 signaling: recruitment and activation of multiple protein tyrosine kinases by the components of the IL-2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Different interleukin 2 receptor beta-chain tyrosines couple to at least two signaling pathways and synergistically mediate interleukin 2-induced proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

New role for Shc in activation of the phosphatidylinositol 3-kinase/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

The p66shc adaptor protein controls oxidative stress response and life span in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Shc interaction with Src homology 2 domain containing inositol phosphatase (SHIP) in vivo requires the Shc-phosphotyrosine binding domain and two specific phosphotyrosines on SHIP

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

The inositol polyphosphate 5-phosphatase ship is a crucial negative regulator of B cell antigen receptor signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Cloning and characterization of mPAL, a novel Shc SH2 domain-binding protein expressed in proliferating cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Membrane compartmentation is required for efficient T cell activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Different initiation of pre-TCR and gammadeltaTCR signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Modeling and analysis on the internal impact of a Stewart platform utilized for spacecraft docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

A comparison of the interaction of Shc and the tyrosine kinase ZAP-70 with the T cell antigen receptor zeta chain tyrosine-based activation motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Shc: a dominant player after ten seasons

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

Complex complexes: signaling at the TCR.

21 January 2018

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Ordered just so: lipid rafts and lymphocyte function

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Lymphocyte antigen receptor signal integration and regulation by the SHC adaptor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Solution structure of the Shc SH2 domain complexed with a tyrosine-phosphorylated peptide from the T-cell receptor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Regulation of T cell receptor signaling by tyrosine phosphatase SYP association with CTLA-4

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Molecular determinants in pleckstrin homology domains that allow specific recognition of phosphoinositides

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Interaction of Shc with Grb2 regulates the Grb2 association with mSOS

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Crucial function of the pre-T-cell receptor (TCR) in TCR beta selection, TCR beta allelic exclusion and alpha beta versus gamma delta lineage commitment

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

T cell development: bottoms-up

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

A nonredundant role for the adapter protein Shc in thymic T cell development

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Targeted oncogene activation by site-specific recombination in transgenic mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Inducible gene targeting in mice

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

CD3 epsilon-mediated signals rescue the development of CD4+CD8+ thymocytes in RAG-2-/- mice in the absence of TCR beta chain expression.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Interleukin-2 signaling and the maintenance of self-tolerance

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

IL-2 signaling involves recruitment and activation of multiple protein tyrosine kinases by the IL-2 receptor

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Uncoupling IL-2 signals that regulate T cell proliferation, survival, and Fas-mediated activation-induced cell death

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Deficient T cell fate specification in mice with an induced inactivation of Notch1.

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Targeted disruption of SHIP leads to hemopoietic perturbations, lung pathology, and a shortened life span

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

Structure and function of membrane rafts

1 reference

https://api.crossref.org/works/10.1034%2FJ.1600-065X.2003.00025.X

7 January 2021

10.1034/J.1600-065X.2003.00025.X

Identifiers

DOI

1 reference

16 June 2017

1 reference