(Q30341660)

20 June 2017

title

Analysis of somatic hypermutation and antigenic selection in the clonal B cell in immunoglobulin light chain amyloidosis (AL). (English)

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20 June 2017

5

Morie A Gertz

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20 June 2017

Roshini S Abraham

1

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20 June 2017

Susan M Geyer

2

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20 June 2017

Marina Ramírez-Alvarado

3

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20 June 2017

Tammy L Price-Troska

4

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20 June 2017

Rafael Fonseca

6

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20 June 2017

publication date

1 July 2004

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Journal of Clinical Immunology

20 June 2017

published in

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20 June 2017

volume

24

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20 June 2017

issue

4

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20 June 2017

page(s)

340-353

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Clonal evolution of a follicular lymphoma: evidence for antigen selection

20 June 2017

cites work

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12 December 2020

The targeting of somatic hypermutation

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12 December 2020

Towards an understanding of somatic hypermutation

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12 December 2020

Ongoing immunoglobulin somatic mutation in germinal center B cell-like but not in activated B cell-like diffuse large cell lymphomas

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12 December 2020

Tertiary structure of human lambda 6 light chains

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12 December 2020

Structure and function of anti-DNA autoantibodies derived from a single autoimmune mouse

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12 December 2020

Myeloma VL and VH gene sequences reveal a complementary imprint of antigen selection in tumor cells.

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12 December 2020

Specificity of abnormal assembly in immunoglobulin light chain deposition disease and amyloidosis

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12 December 2020

Thermodynamic instability of human lambda 6 light chains: correlation with fibrillogenicity

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12 December 2020

Growth of beta-amyloid(1-40) protofibrils by monomer elongation and lateral association. Characterization of distinct products by light scattering and atomic force microscopy.

1 reference

12 December 2020

Mechanisms of disease: monoclonal immunoglobulin deposition. Amyloidosis, light chain deposition disease, and light and heavy chain deposition disease

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12 December 2020

Clonal evolution in Waldenstrom macroglobulinemia highlights functional role of B-cell receptor

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12 December 2020

Measurement of the β-sheet-forming propensities of amino acids

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12 December 2020

Mobilized CD34+ cells selected as autografts in patients with primary light-chain amyloidosis: rationale and application

1 reference

12 December 2020

Bence Jones proteins and light chains of immunoglobulins. Preferential association of the V lambda VI subgroup of human light chains with amyloidosis AL (lambda).

1 reference

12 December 2020

Inter- and intraclonal diversity in the antibody response to influenza hemagglutinin

1 reference

12 December 2020

The tropism of organ involvement in primary systemic amyloidosis: contributions of Ig V(L) germ line gene use and clonal plasma cell burden

1 reference

12 December 2020

Molecular analysis of immunoglobulin genes in diffuse large B-cell lymphomas.

1 reference

12 December 2020

Mutational effects on inclusion body formation in the periplasmic expression of the immunoglobulin VL domain REI

1 reference

12 December 2020

Analysis of the frequency and pattern of somatic mutations within nonproductively rearranged human variable heavy chain genes.

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12 December 2020

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12 December 2020

Secondary amyloidosis (AA)

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12 December 2020

Tertiary structure of an amyloid immunoglobulin light chain protein: a proposed model for amyloid fibril formation

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12 December 2020

Somatic hypermutagenesis in immunoglobulin genes. II. Influence of neighbouring base sequences on mutagenesis

1 reference

12 December 2020

Advancement of multiple myeloma from diagnosis through plateau phase to progression does not involve a new B-cell clone: evidence from the Ig heavy chain gene.

1 reference

12 December 2020

An analysis of the sequences of the variable regions of Bence Jones proteins and myeloma light chains and their implications for antibody complementarity

1 reference

12 December 2020

Overrepresentation of the V kappa IV subgroup in light chain deposition disease

1 reference

12 December 2020

Amino acid sequence based PCR primers for amplification of rearranged human heavy and light chain immunoglobulin variable region genes

1 reference

12 December 2020

Domain stability in immunoglobulin light chain deposition disorders.

1 reference

12 December 2020

Typical Waldenstrom macroglobulinemia is derived from a B-cell arrested after cessation of somatic mutation but prior to isotype switch events

1 reference

12 December 2020

Recombinant immunoglobulin variable domains generated from synthetic genes provide a system for in vitro characterization of light-chain amyloid proteins

1 reference

12 December 2020

Clonal evolution of B cells in transformation from low- to high-grade lymphoma

1 reference

12 December 2020

Immunoglobulin light chain variable (V) region genes influence clinical presentation and outcome in light chain-associated amyloidosis (AL).

1 reference

12 December 2020

Pathogenic light chains and the B-cell repertoire

1 reference

12 December 2020

The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement

1 reference

12 December 2020

Origin of nodular lymphocyte-predominant Hodgkin's disease from a clonal expansion of highly mutated germinal-center B cells

1 reference

12 December 2020

Sporadic and familial cerebral amyloid angiopathies.

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12 December 2020

Destabilizing loop swaps in the CDRs of an immunoglobulin VL domain

1 reference

12 December 2020

Polymorphism in a kappa I primary (AL) amyloid protein (BAN)

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12 December 2020

Ig VH gene mutational patterns indicate different tumor cell status in human myeloma and monoclonal gammopathy of undetermined significance.

1 reference

12 December 2020

Evidence that amyloidogenic light chains undergo antigen-driven selection

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12 December 2020

The role of clonal selection and somatic mutation in autoimmunity

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12 December 2020

Evidence that multiple myeloma Ig heavy chain VDJ genes contain somatic mutations but show no intraclonal variation

1 reference

12 December 2020

Intrinsic beta-sheet propensities result from van der Waals interactions between side chains and the local backbone

1 reference

12 December 2020

Analysis of V(lambda)-J(lambda) expression in plasma cells from primary (AL) amyloidosis and normal bone marrow identifies 3r (lambdaIII) as a new amyloid-associated germline gene segment

1 reference

12 December 2020

Myeloma Ig heavy chain V region sequences reveal prior antigenic selection and marked somatic mutation but no intraclonal diversity.

1 reference

12 December 2020

Clonal immunoglobulin light chain variable region germline gene use in AL amyloidosis: association with dominant amyloid-related organ involvement and survival after stem cell transplantation

1 reference

12 December 2020

Evolutionary nucleotide replacements in DNA

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12 December 2020

Chronic lymphocytic leukemia B cells can undergo somatic hypermutation and intraclonal immunoglobulin V(H)DJ(H) gene diversification.

1 reference

12 December 2020

Familial amyloidosis: a study of 52 North American-born patients examined during a 30-year period

1 reference

12 December 2020

Role of proprotein convertases in the pathogenic processing of the amyloidosis-associated form of secretory gelsolin

1 reference

12 December 2020

Inhibition of amyloid fiber assembly by both BiP and its target peptide

1 reference

12 December 2020

A role for destabilizing amino acid replacements in light-chain amyloidosis

1 reference

12 December 2020

In vitro immunoglobulin light chain fibrillogenesis

1 reference

12 December 2020

10.1023/B:JOCI.0000029113.68758.9F

Identifiers

DOI

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Dimensions Publication ID

20 June 2017

1017474584

0 references

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