(Q30370310)

21 June 2017

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title

Signaling networks during development: the case of asymmetric cell division in the Drosophila nervous system. (English)

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21 June 2017

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asymmetric cell division

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Ana Carmena

1

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21 June 2017

language of work or name

English

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publication date

14 June 2008

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21 June 2017

published in

Developmental Biology

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21 June 2017

volume

321

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21 June 2017

issue

1

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21 June 2017

page(s)

1-17

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Interaction of PAR-6 with CDC-42 is required for maintenance but not establishment of PAR asymmetry in C. elegans

21 June 2017

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Drosophila neuroblast asymmetric divisions: cell cycle regulators, asymmetric protein localization, and tumorigenesis

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7 January 2021

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Frizzled signalling controls orientation of asymmetric sense organ precursor cell divisions in Drosophila

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A protein interaction map of Drosophila melanogaster

7 January 2021

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Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles

7 January 2021

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7 January 2021

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7 January 2021

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Polarity controls forces governing asymmetric spindle positioning in the Caenorhabditis elegans embryo

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The distribution of active force generators controls mitotic spindle position

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Control of daughter cell fates during asymmetric division: interaction of Numb and Notch

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Scribble associates with two polarity proteins, Lgl2 and Vangl2, via distinct molecular domains

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Rotation and asymmetry of the mitotic spindle direct asymmetric cell division in the developing central nervous system.

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Drosophila neuralized is a ubiquitin ligase that promotes the internalization and degradation of delta

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Lethal giant larvae controls the localization of notch-signaling regulators numb, neuralized, and Sanpodo in Drosophila sensory-organ precursor cells

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Unequal segregation of Neuralized biases Notch activation during asymmetric cell division

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Asymmetric cell divisions promote stratification and differentiation of mammalian skin

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Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation.

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Lgl, Pins and aPKC regulate neuroblast self-renewal versus differentiation.

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Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal

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Discs-Large and Strabismus are functionally linked to plasma membrane formation

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Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways

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A gene complex controlling segmentation in Drosophila

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Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis

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A map of the interactome network of the metazoan C. elegans

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Genomics, gene expression and DNA arrays

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Modes of protein movement that lead to the asymmetric localization of partner of Numb during Drosophila neuroblast division

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Control of cell divisions in the nervous system: symmetry and asymmetry

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Roles of aurora-A kinase in mitotic entry and G2 checkpoint in mammalian cells.

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Drosophila genome-wide RNAi screens: are they delivering the promise?

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Cdc2-cyclin B triggers H3 kinase activation of Aurora-A in Xenopus oocytes

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Binding of APC to the human homolog of the Drosophila discs large tumor suppressor protein.

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Quantitative analysis of protein dynamics during asymmetric cell division

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hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells

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canoe encodes a novel protein containing a GLGF/DHR motif and functions with Notch and scabrous in common developmental pathways in Drosophila

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Identification and cDNA cloning of a novel human mosaic protein, LGN, based on interaction with G alpha i2

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Building mammalian signalling pathways with RNAi screens

7 January 2021

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Association of the kinesin superfamily motor protein KIF1Balpha with postsynaptic density-95 (PSD-95), synapse-associated protein-97, and synaptic scaffolding molecule PSD-95/discs large/zona occludens-1 proteins

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Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions

7 January 2021

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Cortical flows powered by asymmetrical contraction transport PAR proteins to establish and maintain anterior-posterior polarity in the early C. elegans embryo

7 January 2021

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Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells

7 January 2021

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Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase

7 January 2021

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Modeling of signaling networks

7 January 2021

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Role of numb in dendritic spine development with a Cdc42 GEF intersectin and EphB2.

7 January 2021

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Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development.

7 January 2021

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Mutations affecting segment number and polarity in Drosophila

7 January 2021

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Role of cortical tumour-suppressor proteins in asymmetric division of Drosophila neuroblast

7 January 2021

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Proteomics to study genes and genomes

7 January 2021

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Reconstruction of cellular signalling networks and analysis of their properties

7 January 2021

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Microtubule binding by CRIPT and its potential role in the synaptic clustering of PSD-95

7 January 2021

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neuralized Encodes a peripheral membrane protein involved in delta signaling and endocytosis.

7 January 2021

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Anterior-posterior polarity in C. elegans and Drosophila--PARallels and differences

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The tumour-suppressor genes lgl and dlg regulate basal protein targeting in Drosophila neuroblasts

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Drug-target identification in Drosophila cells: combining high-throughout RNAi and small-molecule screens

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Progenitor cell maintenance requires numb and numblike during mouse neurogenesis

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Cdc42 regulates the Par-6 PDZ domain through an allosteric CRIB-PDZ transition

7 January 2021

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The Drosophila myosin VI Jaguar is required for basal protein targeting and correct spindle orientation in mitotic neuroblasts.

7 January 2021

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DmPAR-6 directs epithelial polarity and asymmetric cell division of neuroblasts in Drosophila

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A polarity complex of mPar-6 and atypical PKC binds, phosphorylates and regulates mammalian Lgl.

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Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Noninvasive quantitative imaging of protein-protein interactions in living subjects

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Functionally unequal centrosomes drive spindle orientation in asymmetrically dividing Drosophila neural stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

A generic protein purification method for protein complex characterization and proteome exploration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Regulation of membrane localization of Sanpodo by lethal giant larvae and neuralized in asymmetrically dividing cells of Drosophila sensory organs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Two types of asymmetric divisions in the Drosophila sensory organ precursor cell lineage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Drosophila aPKC regulates cell polarity and cell proliferation in neuroblasts and epithelia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

A role for a novel centrosome cycle in asymmetric cell division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

The LAP family: a phylogenetic point of view

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Heterotrimeric G proteins direct two modes of asymmetric cell division in the Drosophila nervous system

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

PDZ domains and the organization of supramolecular complexes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Microtubule-induced Pins/Galphai cortical polarity in Drosophila neuroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Extrinsic cues orient the cell division axis in Drosophila embryonic neuroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Plane of cell cleavage and numb distribution during cell division relative to cell differentiation in the developing retina.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Asymmetric localisation of Miranda and its cargo proteins during neuroblast division requires the anaphase-promoting complex/cyclosome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

aPKC-mediated phosphorylation regulates asymmetric membrane localization of the cell fate determinant Numb

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

A high efficiency strategy for binding property characterization of peptide-binding domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Recognition of unique carboxyl-terminal motifs by distinct PDZ domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Numb antagonizes Notch signaling to specify sibling neuron cell fates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

The PDZ protein Canoe regulates the asymmetric division of Drosophila neuroblasts and muscle progenitors.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Robustness of cellular functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Light microscopy techniques for live cell imaging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

PDZ domain binding selectivity is optimized across the mouse proteome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

The Drosophila lethal(2)giant larvae tumor suppressor protein forms homo-oligomers and is associated with nonmuscle myosin II heavy chain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Live cell imaging using wide-field microscopy and deconvolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Receptor-independent activators of heterotrimeric G-protein signaling pathways

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

cdc2 links the Drosophila cell cycle and asymmetric division machineries

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

What do we learn from high-throughput protein interaction data?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

The molluscan RING-finger protein L-TRIM is essential for neuronal outgrowth

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Mammalian NUMB is an evolutionarily conserved signaling adapter protein that specifies cell fate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

APC/C and SCF: controlling each other and the cell cycle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Direct association of Bazooka/PAR-3 with the lipid phosphatase PTEN reveals a link between the PAR/aPKC complex and phosphoinositide signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

NUMB localizes in the basal cortex of mitotic avian neuroepithelial cells and modulates neuronal differentiation by binding to NOTCH-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Polo inhibits progenitor self-renewal and regulates Numb asymmetry by phosphorylating Pon.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Aurora-A acts as a tumor suppressor and regulates self-renewal of Drosophila neuroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

A PtdInsP(3)- and Rho GTPase-mediated positive feedback loop regulates neutrophil polarity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

A Rich1/Amot complex regulates the Cdc42 GTPase and apical-polarity proteins in epithelial cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Mitotic spindle orientation distinguishes stem cell and terminal modes of neuron production in the early spinal cord.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Between "design" and "bricolage": genetic networks, levels of selection, and adaptive evolution

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Asymmetric cell division during neurogenesis in Drosophila and vertebrates.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Drosophila atypical protein kinase C associates with Bazooka and controls polarity of epithelia and neuroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

The discs-large tumor suppressor gene of Drosophila encodes a guanylate kinase homolog localized at septate junctions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

PDZ domains of Par-3 as potential phosphoinositide signaling integrators

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Mammalian Lgl Forms a Protein Complex with PAR-6 and aPKC Independently of PAR-3 to Regulate Epithelial Cell Polarity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Asymmetric centrosome behavior and the mechanisms of stem cell division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Asymmetric inheritance of mother versus daughter centrosome in stem cell division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Neuralized functions as an E3 ubiquitin ligase during Drosophila development

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Diversifying neural cells through order of birth and asymmetry of division

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

Mammalian inscuteable regulates spindle orientation and cell fate in the developing retina

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

PIP(2)-PDZ domain binding controls the association of syntenin with the plasma membrane

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2008.06.010

10.1016/J.YDBIO.2008.06.010

7 January 2021

Identifiers

DOI

1 reference

21 June 2017

1 reference