(Q30403510)

English

Folding dynamics of phenylalanine hydroxylase depends on the enzyme's metallation state: the native metal, iron, protects against aggregate intermediates

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Folding dynamics of phenylalanine hydroxylase depends on the enzyme's metallation state: the native metal, iron, protects against aggregate intermediates (English)

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

author name string

Aristobulo Loaiza

1

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Judith A Ronau

2

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Alexander Ribbe

3

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Lia Stanciu

4

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

John W Burgner

5

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Lake N Paul

6

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

Mahdi M Abu-Omar

7

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

publication date

7 June 2011

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Europe PubMed Central

PubMed publication ID

21 June 2017

European Biophysics Journal

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Europe PubMed Central

PubMed publication ID

21 June 2017

40

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Europe PubMed Central

PubMed publication ID

21 June 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

959-968

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

https://scigraph.springernature.com/pub.10.1007/s00249-011-0711-6

0 references

Reaction mechanisms of mononuclear non-heme iron oxygenases

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria.

1 reference

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21 January 2018

Macromolecular size-and-shape distributions by sedimentation velocity analytical ultracentrifugation.

1 reference

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21 January 2018

Mechanism of metal-independent hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase

1 reference

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21 January 2018

The structural basis of phenylketonuria

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Structural comparison of bacterial and human iron-dependent phenylalanine hydroxylases: similar fold, different stability and reaction rates

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Phi-value analysis and the nature of protein-folding transition states

1 reference

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21 January 2018

Mechanism of aromatic amino acid hydroxylation

1 reference

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Structure of tetrameric human phenylalanine hydroxylase and its implications for phenylketonuria

1 reference

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21 January 2018

Loss of function in phenylketonuria is caused by impaired molecular motions and conformational instability

1 reference

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In vitro expression of 34 naturally occurring mutant variants of phenylalanine hydroxylase: correlation with metabolic phenotypes and susceptibility toward protein aggregation

1 reference

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Conformational states of beta-lactamase: molten-globule states at acidic and alkaline pH with high salt

1 reference

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Structural basis of autoregulation of phenylalanine hydroxylase

1 reference

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A study of the adsorption of dyes on bovine serum albumin by the method of polarization of fluorescence

1 reference

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Protein misfolding in conformational disorders: rescue of folding defects and chemical chaperoning

1 reference

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A reference database for circular dichroism spectroscopy covering fold and secondary structure space.

1 reference

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21 January 2018

Kinetics of thermal unfolding of phenylalanine hydroxylase variants containing different metal cofactors (FeII, CoII, and ZnII) and their isokinetic relationship

1 reference

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21 January 2018

Rescuing proteins of low kinetic stability by chaperones and natural ligands phenylketonuria, a case study

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Submolecular unfolding units of Pseudomonas aeruginosa cytochrome c-551.

1 reference

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Equilibrium unfolding of neuronal calcium sensor-1: N-terminal myristoylation influences unfolding and reduces protein stiffening in the presence of calcium

1 reference

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21 January 2018

Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding

1 reference

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21 January 2018

The accessibility of iron at the active site of recombinant human phenylalanine hydroxylase to water as studied by 1H NMR paramagnetic relaxation. Effect of L-Phe and comparison with the rat enzyme

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Kinetic isotope effects on aromatic and benzylic hydroxylation by Chromobacterium violaceum phenylalanine hydroxylase as probes of chemical mechanism and reactivity

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Iron binding effects on the kinetic stability and unfolding energetics of a thermophilic phenylalanine hydroxylase from Chloroflexus aurantiacus

1 reference

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21 January 2018

Phenylketonuria: genotype-phenotype correlations based on expression analysis of structural and functional mutations in PAH.

1 reference

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21 January 2018

Predicted effects of missense mutations on native-state stability account for phenotypic outcome in phenylketonuria, a paradigm of misfolding diseases

1 reference

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21 January 2018

Size-Distribution Analysis of Macromolecules by Sedimentation Velocity Ultracentrifugation and Lamm Equation Modeling

1 reference

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21 January 2018

In vitro unfolding of yeast multicopper oxidase Fet3p variants reveals unique role of each metal site

1 reference

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21 January 2018

L-phenylalanine binding and domain organization in human phenylalanine hydroxylase: a differential scanning calorimetry study.

1 reference

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21 January 2018

Order of substrate binding in bacterial phenylalanine hydroxylase and its mechanistic implication for pterin-dependent oxygenases

1 reference

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21 January 2018

Characterization of phenylketonuria missense substitutions, distant from the phenylalanine hydroxylase active site, illustrates a paradigm for mechanism and potential modulation of phenotype

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Polarization of the fluorescence of macromolecules. II. Fluorescent conjugates of ovalbumin and bovine serum albumin

1 reference

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21 January 2018

Circular dichroism of protein-folding intermediates

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Effect of temperature, pH, and metals on the stability and activity of phenylalanine hydroxylase from Chromobacterium violaceum

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Pterin-Dependent Amino Acid Hydroxylases

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Impact of cofactor on stability of bacterial (CopZ) and human (Atox1) copper chaperones

1 reference

https://api.crossref.org/works/10.1007%2FS00249-011-0711-6

21 January 2018

Urea-induced denaturation of human phenylalanine hydroxylase

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

12 December 2020

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Viscosity and density of aqueous solutions of urea and guanidine hydrochloride

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

12 December 2020

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Expression analysis of phenylketonuria mutations. Effect on folding and stability of the phenylalanine hydroxylase protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

12 December 2020

based on heuristic

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Phenylalanine hydroxylase from Chromobacterium violaceum. Uncoupled oxidation of tetrahydropterin and the role of iron in hyroxylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

12 December 2020

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Tryptophan fluorescence of human phenylalanine hydroxylase produced in Escherichia coli

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

12 December 2020

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Structure and stability of an early folding intermediate of Escherichia coli trp aporepressor measured by far-UV stopped-flow circular dichroism and 8-anilino-1-naphthalene sulfonate binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

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based on heuristic

inferred from PubMed ID database lookup

Phenylalanine hydroxylase from Chromobacterium violaceum is a copper-containing monooxygenase. Kinetics of the reductive activation of the enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/21647679

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00249-011-0711-6

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

21 June 2017

ResearchGate publication ID

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