(Q30419946)

English

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1

scientific article

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scholarly article

1 reference

Europe PubMed Central

16 August 2017

Site-specific phosphorylation of the DNA damage response mediator rad9 by cyclin-dependent kinases regulates activation of checkpoint kinase 1 (English)

1 reference

Europe PubMed Central

16 August 2017

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

Jeffrey Shabanowitz

11

object named as

Jeffrey Shabanowitz

0 references

Jeremy L Balsbaugh

object named as

Jeremy Lynn Balsbaugh

8

0 references

object named as

Muriel Grenon

13

0 references

Noel F. Lowndes

object named as

Noel Francis Lowndes

14

0 references

Rosemary O'Connor

object named as

Rosemary O'Connor

9

0 references

object named as

Carla Manuela Abreu

1

0 references

author name string

Ramesh Kumar

2

1 reference

Europe PubMed Central

16 August 2017

Danielle Hamilton

3

1 reference

Europe PubMed Central

16 August 2017

Andrew William Dawdy

4

1 reference

Europe PubMed Central

16 August 2017

Kevin Creavin

5

1 reference

Europe PubMed Central

16 August 2017

Sarah Eivers

6

1 reference

Europe PubMed Central

16 August 2017

Karen Finn

7

1 reference

Europe PubMed Central

16 August 2017

Patrick A Kiely

10

1 reference

Europe PubMed Central

16 August 2017

Donald F Hunt

12

1 reference

Europe PubMed Central

16 August 2017

publication date

4 April 2013

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

9

1 reference

Europe PubMed Central

16 August 2017

4

1 reference

Europe PubMed Central

16 August 2017

e1003310

1 reference

Europe PubMed Central

16 August 2017

copyright license

Creative Commons Attribution 4.0 International

4 April 2013

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April 2022 Public Data File from Crossref

copyright status

0 references

Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint

1 reference

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20 June 2018

Antitumor effect of berberine against primary effusion lymphoma via inhibition of NF-κB pathway.

1 reference

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20 June 2018

Eukaryotic DNA damage checkpoint activation in response to double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Dpb11 coordinates Mec1 kinase activation with cell cycle-regulated Rad9 recruitment

1 reference

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20 June 2018

Role for casein kinase 1 in the phosphorylation of Claspin on critical residues necessary for the activation of Chk1.

1 reference

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20 June 2018

Dynamics of Cdk1 substrate specificity during the cell cycle

1 reference

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20 June 2018

Multiple functions of the S-phase checkpoint mediator

1 reference

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20 June 2018

Checkpoint genes and Exo1 regulate nearby inverted repeat fusions that form dicentric chromosomes in Saccharomyces cerevisiae

1 reference

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20 June 2018

Dynamics of Rad9 chromatin binding and checkpoint function are mediated by its dimerization and are cell cycle-regulated by CDK1 activity

1 reference

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20 June 2018

14-3-3gamma mediates Cdc25A proteolysis to block premature mitotic entry after DNA damage

1 reference

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20 June 2018

Mechanisms of ATR-mediated checkpoint signalling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

The Saccharomyces cerevisiae RAD9, RAD17 and RAD24 genes are required for suppression of mutagenic post-replicative repair during chronic DNA damage.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

An overview of Cdk1-controlled targets and processes

1 reference

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20 June 2018

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

1 reference

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20 June 2018

MDC1: The art of keeping things in focus

1 reference

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20 June 2018

A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

53BP1: function and mechanisms of focal recruitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Taking the time to make important decisions: the checkpoint effector kinases Chk1 and Chk2 and the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Behind the wheel and under the hood: functions of cyclin-dependent kinases in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

A tale of two tails: activation of DNA damage checkpoint kinase Mec1/ATR by the 9-1-1 clamp and by Dpb11/TopBP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Regulation of chk1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Maintenance of the DNA-damage checkpoint requires DNA-damage-induced mediator protein oligomerization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

CDK targets Sae2 to control DNA-end resection and homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Phosphorylation of the budding yeast 9-1-1 complex is required for Dpb11 function in the full activation of the UV-induced DNA damage checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

A multidimensional chromatography technology for in-depth phosphoproteome analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

An oncogene-induced DNA damage model for cancer development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

The DNA damage response: ten years after

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Rad9 BRCT domain interaction with phosphorylated H2AX regulates the G1 checkpoint in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Clustering of phosphorylation site recognition motifs can be exploited to predict the targets of cyclin-dependent kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

DNA damage checkpoints are involved in postreplication repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Signal transduction: how rad53 kinase is activated

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

DNA end resection, homologous recombination and DNA damage checkpoint activation require CDK1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Chk1 in the DNA damage response: conserved roles from yeasts to mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Targets of the cyclin-dependent kinase Cdk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

The budding yeast Rad9 checkpoint complex: chaperone proteins are required for its function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Establishment of and recovery from damage checkpoint requires sequential interactions of Crb2 with protein kinases Rad3, Chk1, and Cdc2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

MDC1 is coupled to activated CHK2 in mammalian DNA damage response pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

NFBD1/KIAA0170 is a chromatin-associated protein involved in DNA damage signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Kinetochore localisation of the DNA damage response component 53BP1 during mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Multisite phosphorylation of a CDK inhibitor sets a threshold for the onset of DNA replication

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Checkpoint activation in response to double-strand breaks requires the Mre11/Rad50/Xrs2 complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Tumor suppressor p53 binding protein 1 (53BP1) is involved in DNA damage-signaling pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Negative cell cycle regulation and DNA damage-inducible phosphorylation of the BRCT protein 53BP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

A chemical switch for inhibitor-sensitive alleles of any protein kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

BRCA1 is phosphorylated at serine 1497 in vivo at a cyclin-dependent kinase 2 phosphorylation site

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Damage and replication checkpoint control in fission yeast is ensured by interactions of Crb2, a protein with BRCT motif, with Cut5 and Chk1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Persistent initiation of DNA replication and chromatin-bound MCM proteins during the cell cycle in cdc6 mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

BRCA1 is a cell cycle-regulated nuclear phosphoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Isolation and characterization of the Schizosaccharomyces pombe rhp9 gene: a gene required for the DNA damage checkpoint but not the replication checkpoint

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Activation of S-phase-promoting CDKs in late G1 defines a "point of no return" after which Cdc6 synthesis cannot promote DNA replication in yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

An essential role for the Cdc6 protein in forming the pre-replicative complexes of budding yeast

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

The B-type cyclin kinase inhibitor p40SIC1 controls the G1 to S transition in S. cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

The RAD9 gene controls the cell cycle response to DNA damage in Saccharomyces cerevisiae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

20 June 2018

Multiple approaches to study S. cerevisiae Rad9, a prototypical checkpoint protein.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

Budding yeast Rad9 is an ATP-dependent Rad53 activating machine.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

ATRMec1 phosphorylation-independent activation of Chk1 in vivo

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

A domain of Rad9 specifically required for activation of Chk1 in budding yeast

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

Cyclin specificity in the phosphorylation of cyclin-dependent kinase substrates.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

Docking onto chromatin via the Saccharomyces cerevisiae Rad9 Tudor domain.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

Spreading the signal: dissociation of Chk1 from chromatin.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1003310

21 January 2018

Histone H2A phosphorylation and H3 methylation are required for a novel Rad9 DSB repair function following checkpoint activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3616908

26 November 2018

MEC1-dependent phosphorylation of Rad9p in response to DNA damage

1 reference

https://pubmed.ncbi.nlm.nih.gov/23593009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Saccharomyces cerevisiae DNA damage checkpoint is required for efficient repair of double strand breaks by non-homologous end joining

1 reference

https://pubmed.ncbi.nlm.nih.gov/23593009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of the DNA damage checkpoint by chk1 and rad53 protein kinases through distinct mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/23593009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cdc2 Phosphorylation of Crb2 Is Required for Reestablishing Cell Cycle Progression after the Damage Checkpoint

1 reference

https://pubmed.ncbi.nlm.nih.gov/23593009

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PGEN.1003310

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

1 reference

Europe PubMed Central

16 August 2017

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