(Q30441111)

16870734

21 June 2017

title

Neural-specific inactivation of ShcA results in increased embryonic neural progenitor apoptosis and microencephaly (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

5

James W Mandell

1 reference

21 June 2017

4

Kodi S Ravichandran

1 reference

21 June 2017

Karen N McFarland

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

Steven R Wilkes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

Sarah E Koss

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

Kodi S Ravichandran

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

James W Mandell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

language of work or name

English

0 references

publication date

1 July 2006

1 reference

16870734

21 June 2017

published in

Journal of Neuroscience

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

volume

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

issue

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

page(s)

7885-7897

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

describes a project that uses

11 May 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6674223/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

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12 December 2020

Primary autosomal recessive microcephaly: homozygosity mapping of MCPH4 to chromosome 15.

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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Defective neural tube morphogenesis and altered apoptosis in the absence of both JNK1 and JNK2.

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The second locus for autosomal recessive primary microcephaly (MCPH2) maps to chromosome 19q13.1-13.2.

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12 December 2020

The p66shc adaptor protein controls oxidative stress response and life span in mammals

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12 December 2020

A third novel locus for primary autosomal recessive microcephaly maps to chromosome 9q34.

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12 December 2020

The ShcA phosphotyrosine docking protein sensitizes cardiovascular signaling in the mouse embryo

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12 December 2020

The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells

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12 December 2020

Decreased apoptosis in proliferative and postmitotic regions of the Caspase 3-deficient embryonic central nervous system

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12 December 2020

Evolution of Shc functions from nematode to human

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12 December 2020

The subventricular zone: source of neuronal precursors for brain repair.

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The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons

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Expression of active caspase-3 in mitotic and postmitotic cells of the rat forebrain

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12 December 2020

Shc signaling in differentiating neural progenitor cells.

1 reference

12 December 2020

Prenatal ionizing radiation-induced apoptosis of the developing murine brain with special references to the expression of some proteins

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12 December 2020

Signaling via Shc family adapter proteins

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12 December 2020

Transcriptional regulation of cortical neuron migration by POU domain factors

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12 December 2020

Identification of microcephalin, a protein implicated in determining the size of the human brain

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12 December 2020

A nonredundant role for the adapter protein Shc in thymic T cell development

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12 December 2020

CFC index for the diagnosis of cardiofaciocutaneous syndrome

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12 December 2020

Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.

1 reference

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Multiple dose-dependent effects of Lis1 on cerebral cortical development

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Cell and molecular mechanisms that control cortical layer formation in the brain.

1 reference

12 December 2020

Endogenously produced neurotrophins regulate survival and differentiation of cortical progenitors via distinct signaling pathways.

1 reference

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A novel locus for autosomal recessive primary microcephaly (MCPH6) maps to 13q12.2

1 reference

12 December 2020

Cortical and retinal defects caused by dosage-dependent reductions in VEGF-A paracrine signaling

1 reference

12 December 2020

Protein-truncating mutations in ASPM cause variable reduction in brain size

1 reference

12 December 2020

Region of caspase-3 activation and programmed cell death in the early development of the mouse forebrain

1 reference

12 December 2020

Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases

1 reference

12 December 2020

Mitogen-activated protein kinase pathway-dependent tumor-specific survival signaling in melanoma cells through inactivation of the proapoptotic protein bad.

1 reference

12 December 2020

Neural stem and progenitor cells in nestin-GFP transgenic mice

1 reference

12 December 2020

1 reference

12 December 2020

Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation

1 reference

12 December 2020

Mutations in microcephalin cause aberrant regulation of chromosome condensation.

1 reference

12 December 2020

Microcephalin Is a DNA Damage Response Protein Involved in Regulation of CHK1 and BRCA1

1 reference

12 December 2020

Active caspase-3 expression during postnatal development of rat cerebellum is not systematically or consistently associated with apoptosis

1 reference

12 December 2020

Genetic analysis of primary microcephaly in Indian families: novel ASPM mutations

1 reference

12 December 2020

Roles of the mammalian subventricular zone in cell replacement after brain injury

1 reference

12 December 2020

Molecular morphology of neuronal apoptosis: Analysis of caspase 3 activation during postnatal development of mouse cerebellar cortex

1 reference

12 December 2020

Inactivation of bad by site-specific phosphorylation: the checkpoint for ischemic astrocytes to initiate or resist apoptosis.

1 reference

12 December 2020

p66SHC: the apoptotic side of Shc proteins

1 reference

12 December 2020

A centrosomal mechanism involving CDK5RAP2 and CENPJ controls brain size

1 reference

12 December 2020

Comparative expression profiles of ShcB and ShcC phosphotyrosine adapter molecules in the adult brain

1 reference

12 December 2020

Essential role for survivin in early brain development

1 reference

12 December 2020

A novel transforming protein (SHC) with an SH2 domain is implicated in mitogenic signal transduction

1 reference

12 December 2020

Expression of Cux-1 and Cux-2 in the developing somatosensory cortex of normal and barrel-defective mice

1 reference

12 December 2020

Germline mutations in genes within the MAPK pathway cause cardio-facio-cutaneous syndrome

1 reference

12 December 2020

CNS stem cells express a new class of intermediate filament protein

1 reference

12 December 2020

Estimation of nuclear population from microtome sections

1 reference

12 December 2020

Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry

1 reference

12 December 2020

1 reference

12 December 2020

Glutamate-like Immunoreactivity and Fate of Cajal-Retzius Cells in the Murine Cortex as Identified with Calretinin Antibody

1 reference

12 December 2020

Chromosome locations of genes encoding human signal transduction adapter proteins, Nck (NCK), Shc (SHC1), and Grb2 (GRB2).

1 reference

12 December 2020

Independent regulatory elements in the nestin gene direct transgene expression to neural stem cells or muscle precursors.

1 reference

12 December 2020

UV activates growth factor receptors via reactive oxygen intermediates

1 reference

12 December 2020

A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain

1 reference

12 December 2020

Transcription factor AP-2 essential for cranial closure and craniofacial development

1 reference

12 December 2020

A family of Shc related proteins with conserved PTB, CH1 and SH2 regions

1 reference

12 December 2020

Hydrogen peroxide induces complex formation of SHC-Grb2-SOS with receptor tyrosine kinase and activates Ras and extracellular signal-regulated protein kinases group of mitogen-activated protein kinases

1 reference

12 December 2020

Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

1 reference

12 December 2020

The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions

1 reference

12 December 2020

A novel pathway from phosphorylation of tyrosine residues 239/240 of Shc, contributing to suppress apoptosis by IL-3

1 reference

12 December 2020

Expression and activation of SH2/PTB-containing ShcA adaptor protein reflects the pattern of neurogenesis in the mammalian brain

1 reference

12 December 2020

Mice lacking the ski proto-oncogene have defects in neurulation, craniofacial, patterning, and skeletal muscle development

1 reference

12 December 2020

N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling

1 reference

12 December 2020

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

1 reference

12 December 2020

Emerging roles for SH2/PTB-containing Shc adaptor proteins in the developing mammalian brain.

1 reference

12 December 2020

10.1523/JNEUROSCI.3524-05.2006

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6674223&resulttype=core&format=json

11 May 2020

16870734

1 reference