(Q30442993)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

title

Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

6

Brett R Blackman

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

5

Ian J Sarembock

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

author name string

A Wayne Orr

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Rebecca Stockton

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

Michael B Simmers

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

John M Sanders

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

language of work or name

English

0 references

publication date

20 February 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

number of pages

9

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

volume

176

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

page(s)

719-727

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

Spatial and spectral heterogeneity of time-varying shear stress profiles in the carotid bifurcation by phase-contrast MRI.

25 December 2019

cites work

1 reference

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VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin

14 July 2018

1 reference

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Mechanisms of mechanotransduction.

14 July 2018

1 reference

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Akt1 regulates pathological angiogenesis, vascular maturation and permeability in vivo

14 July 2018

1 reference

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Rho GTPases: biochemistry and biology

14 July 2018

1 reference

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The subendothelial extracellular matrix modulates NF-kappaB activation by flow: a potential role in atherosclerosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

p21-activated kinase regulates endothelial permeability through modulation of contractility.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

The integrin-binding protein Nischarin regulates cell migration by inhibiting PAK.

14 July 2018

1 reference

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Gene expression profiling of vascular endothelial cells exposed to fluid mechanical forces: relevance for focal susceptibility to atherosclerosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Effect of cGMP on lung microvascular endothelial barrier dysfunction following hydrogen peroxide

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Site specificity of atherosclerosis: site-selective responses to atherosclerotic modulators

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Akt Phosphorylation of Serine 21 on Pak1 Modulates Nck Binding and Cell Migration

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Protein kinase signaling in the modulation of microvascular permeability

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Biology of the p21-activated kinases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

p21-activated kinase 1 (PAK1) interacts with the Grb2 adapter protein to couple to growth factor signaling

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Emerging functions of p21-activated kinases in human cancer cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Effect of fluid shear stress on the permeability of the arterial endothelium.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

A dominant-negative p65 PAK peptide inhibits angiogenesis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Thrombospondin stimulates focal adhesion disassembly through Gi- and phosphoinositide 3-kinase-dependent ERK activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

The p21-activated kinase PAK is negatively regulated by POPX1 and POPX2, a pair of serine/threonine phosphatases of the PP2C family

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Activation of integrins in endothelial cells by fluid shear stress mediates Rho-dependent cytoskeletal alignment

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Regulation of the p21-activated kinase (PAK) by a human Gbeta -like WD-repeat protein, hPIP1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

The mechanism of PAK activation. Autophosphorylation events in both regulatory and kinase domains control activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

A role for p21-activated kinase in endothelial cell migration.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Multisite autophosphorylation of p21-activated protein kinase gamma-PAK as a function of activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Atherosclerosis — An Inflammatory Disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Oscillatory and steady laminar shear stress differentially affect human endothelial redox state: role of a superoxide-producing NADH oxidase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Effect of cell shrinkage on permeability of cultured bovine aortic endothelia and frog mesenteric capillaries

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

A critical look at the evidence for the oxidation of LDL in atherogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Possible involvement of phosphorylation of occludin in tight junction formation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Activation of Pak by membrane localization mediated by an SH3 domain from the adaptor protein Nck.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Effect of cell turnover and leaky junctions on arterial macromolecular transport.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Enhanced macromolecular permeability of aortic endothelial cells in association with mitosis.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

IL-1 and IFN-gamma increase vascular permeability.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Tumor necrosis factor/cachectin increases permeability of endothelial cell monolayers by a mechanism involving regulatory G proteins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

cGMP-dependent protein kinase phosphorylates p21-activated kinase (Pak) 1, inhibiting Pak/Nck binding and stimulating Pak/vasodilator-stimulated phosphoprotein association

14 July 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Spatial comparison between wall shear stress measures and porcine arterial endothelial permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Interaction of wall shear stress magnitude and gradient in the prediction of arterial macromolecular permeability.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Role of protein kinase G in barrier-protective effects of cGMP in human pulmonary artery endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Disruption of tumor necrosis factor-alpha gene diminishes the development of atherosclerosis in ApoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Potential role of MCP-1 in endothelial cell tight junction 'opening': signaling via Rho and Rho kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Role of p21-activated kinase pathway defects in the cognitive deficits of Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200609008

Shear stress regulates occludin content and phosphorylation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Integrin-mediated mechanotransduction requires its dynamic interaction with specific extracellular matrix (ECM) ligands

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Junction complexes of endothelial cells in atherosclerosis-prone and atherosclerosis-resistant regions on flow dividers of brachiocephalic bifurcations in the rabbit aorta.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2064028

Laminar shear stress: mechanisms by which endothelial cells transduce an atheroprotective force

26 November 2018

1 reference

12 December 2020

Endothelial albumin permeability is shear dependent, time dependent, and reversible

1 reference

12 December 2020

Absence of monocyte chemoattractant protein-1 reduces atherosclerosis in low density lipoprotein receptor-deficient mice

1 reference

12 December 2020

Mildly oxidized low density lipoprotein induces contraction of human endothelial cells through activation of Rho/Rho kinase and inhibition of myosin light chain phosphatase

1 reference

12 December 2020

Spatial variations in endothelial barrier function in disturbed flows in vitro

1 reference

12 December 2020

A new in vitro model to evaluate differential responses of endothelial cells to simulated arterial shear stress waveforms

1 reference

12 December 2020

Detection of monocyte chemoattractant protein-1 in human atherosclerotic lesions by an anti-monocyte chemoattractant protein-1 monoclonal antibody

1 reference

12 December 2020

Atherosclerosis in mice lacking apo E. Evaluation of lesional development and progression

1 reference

12 December 2020

The distribution of intimal white blood cells in the normal rabbit aorta

1 reference

12 December 2020

Relation between lipopolysaccharide-induced endothelial cell injury and entry of macromolecules into the rat aorta in vivo

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200609008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17312022%20AND%20SRC:MED&resulttype=core&format=json

25 December 2019

PubMed publication ID

17312022

1 reference