(Q30482850)

22 June 2017

title

Use of a cocktail of probe substrates for drug-metabolizing enzymes for the assessment of the metabolic capacity of hepatocyte preparations (English)

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22 June 2017

Floby E

1

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22 June 2017

Briem S

series ordinal

2

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22 June 2017

Terelius Y

series ordinal

3

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22 June 2017

Sohlenius-Sternbeck AK

series ordinal

4

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22 June 2017

language of work or name

English

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publication date

1 November 2004

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22 June 2017

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22 June 2017

volume

34

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22 June 2017

issue

11-12

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22 June 2017

page(s)

949-959

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Prediction of in vivo hepatic clearance from in vitro data using cryopreserved human hepatocytes

22 June 2017

cites work

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Phenotypic stability of adult rat hepatocytes in primary monolayer culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Pharmacokinetic and pharmacodynamic assessment of a five-probe metabolic cocktail for CYPs 1A2, 3A4, 2C9, 2D6 and 2E1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

An update on in vitro test methods in human hepatic drug biotransformation research: pros and cons

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Combined phenotypic assessment of cytochrome p450 1A2, 2C9, 2C19, 2D6, and 3A, N-acetyltransferase-2, and xanthine oxidase activities with the "Cooperstown 5+1 cocktail".

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

The Karolinska cocktail for phenotyping of five human cytochrome P450 enzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

A commentary on the use of hepatocytes in drug metabolism studies during drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Strategies and molecular probes to investigate the role of cytochrome P450 in drug metabolism: focus on in vitro studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Comparisons of catalytic selectivity of cytochrome P450 subfamily enzymes from different species

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Interspecies scaling of tolcapone, a new inhibitor of catechol-O-methyltransferase (COMT). Use of in vitro data from hepatocytes to predict metabolic clearance in animals and humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Utility of Hepatocytes in Predicting Drug Metabolism: Comparison of Hepatic Intrinsic Clearance in Rats and Humans in Vivo and in Vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Human cytochrome P450 enzymes: a status report summarizing their reactions, substrates, inducers, and inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

7-Ethoxycoumarin O-deethylation catalyzed by cytochromes P450 1A2 and 2E1 in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F00498250400017257

10.1080/00498250400017257

21 January 2018

Identifiers

DOI

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22 June 2017

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